JPWO2019234240A5 - - Google Patents
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- JPWO2019234240A5 JPWO2019234240A5 JP2020568390A JP2020568390A JPWO2019234240A5 JP WO2019234240 A5 JPWO2019234240 A5 JP WO2019234240A5 JP 2020568390 A JP2020568390 A JP 2020568390A JP 2020568390 A JP2020568390 A JP 2020568390A JP WO2019234240 A5 JPWO2019234240 A5 JP WO2019234240A5
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- JP
- Japan
- Prior art keywords
- hours
- pharmaceutical composition
- days
- composition according
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000008194 pharmaceutical composition Substances 0.000 claims 35
- 150000003839 salts Chemical class 0.000 claims 25
- 239000011780 sodium chloride Substances 0.000 claims 25
- -1 β-lactam compound Chemical class 0.000 claims 17
- DBABZHXKTCFAPX-UHFFFAOYSA-N Probenecid Chemical compound CCCN(CCC)S(=O)(=O)C1=CC=C(C(O)=O)C=C1 DBABZHXKTCFAPX-UHFFFAOYSA-N 0.000 claims 11
- 229960003081 probenecid Drugs 0.000 claims 11
- 229940000425 combination drugs Drugs 0.000 claims 6
- 239000000203 mixture Substances 0.000 claims 5
- 230000036470 plasma concentration Effects 0.000 claims 3
- 206010046577 Urinary tract infection Diseases 0.000 claims 2
- 201000005661 acute cystitis Diseases 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 201000009910 diseases by infectious agent Diseases 0.000 claims 2
- 125000000547 substituted alkyl group Chemical group 0.000 claims 2
- 206010060968 Arthritis infective Diseases 0.000 claims 1
- 208000008960 Diabetic Foot Diseases 0.000 claims 1
- 206010012742 Diarrhoea infectious Diseases 0.000 claims 1
- 208000001848 Dysentery Diseases 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- 206010065838 Middle ear inflammation Diseases 0.000 claims 1
- 206010031252 Osteomyelitis Diseases 0.000 claims 1
- 206010033078 Otitis media Diseases 0.000 claims 1
- 206010035664 Pneumonia Diseases 0.000 claims 1
- 206010064921 Urinary tract inflammation Diseases 0.000 claims 1
- 235000020828 fasting Nutrition 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 238000007912 intraperitoneal administration Methods 0.000 claims 1
- 201000006518 pelvic inflammatory disease Diseases 0.000 claims 1
- 201000009890 sinusitis Diseases 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862682116P | 2018-06-07 | 2018-06-07 | |
| US62/682,116 | 2018-06-07 | ||
| US201962804970P | 2019-02-13 | 2019-02-13 | |
| US62/804,970 | 2019-02-13 | ||
| PCT/EP2019/065016 WO2019234240A1 (en) | 2018-06-07 | 2019-06-07 | Combinations of beta-lactam compounds and probenecid and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021525787A JP2021525787A (ja) | 2021-09-27 |
| JPWO2019234240A5 true JPWO2019234240A5 (zh) | 2022-06-15 |
Family
ID=67105981
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020568390A Pending JP2021525787A (ja) | 2018-06-07 | 2019-06-07 | β−ラクタム化合物とプロベネシドの組み合わせとその使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11554112B2 (zh) |
| EP (1) | EP3801486A1 (zh) |
| JP (1) | JP2021525787A (zh) |
| CN (1) | CN112739338A (zh) |
| AU (1) | AU2019281018A1 (zh) |
| BR (1) | BR112020024498A2 (zh) |
| TW (1) | TW202005970A (zh) |
| WO (1) | WO2019234240A1 (zh) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2021009755A (es) | 2019-02-13 | 2021-11-17 | Iterum Therapeutics International Ltd | Combinaciones de compuestos beta-lactámicos y probenecid, y usos de los mismos. |
| KR20220152261A (ko) * | 2020-03-11 | 2022-11-15 | 이테룸 테라퓨틱스 인터내셔널 리미티드 | 베타-락탐 화합물, 프로베네시드 및 발프로산의 조합물 및 그의 용도 |
| US11116737B1 (en) | 2020-04-10 | 2021-09-14 | University Of Georgia Research Foundation, Inc. | Methods of using probenecid for treatment of coronavirus infections |
| CA3173187A1 (en) * | 2020-04-10 | 2021-10-14 | Ralph A. Tripp | Methods for treatment of coronavirus infections |
| CN111821462A (zh) * | 2020-08-07 | 2020-10-27 | 安徽康正康仁药业有限公司 | 青霉素类钠盐与丙磺舒钠组成的复方冻干制剂 |
| CN112076161B (zh) * | 2020-08-07 | 2022-10-18 | 安徽康正康仁药业有限公司 | 一种头孢菌素类钠盐与丙磺舒钠组成的复方冻干制剂 |
| CN111840236B (zh) * | 2020-08-07 | 2022-09-02 | 安徽康正康仁药业有限公司 | 一种注射用美罗培南丙磺舒钠复方冻干制剂 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58128387A (ja) * | 1982-01-26 | 1983-07-30 | レオ・フア−マシユ−テイカル・プロダクツ・リミテツド・エイ／エス（レ−ベンス・ケミスケ・フアブリツク・プロデユクチオンスアクチ−セルスカブ） | 新規β−ラクタム化合物およびその製法と用途 |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US5763263A (en) | 1995-11-27 | 1998-06-09 | Dehlinger; Peter J. | Method and apparatus for producing position addressable combinatorial libraries |
| UA59394C2 (uk) | 1998-03-27 | 2003-09-15 | Каділа Фармацевтікелс (І.Ей) Лтд. | Стійка у фіксованих дозах оральна фармацевтична композиція, що містить антибактеріальний засіб і мікроорганізм одночасно, та спосіб її одержання (варіанти) |
| WO2002036126A1 (en) | 2000-10-30 | 2002-05-10 | Lupin Limited | Rapidly disintegrating sustained release cefuroxime axetil composition |
| AU2001227030A1 (en) | 2000-11-22 | 2002-06-03 | Lupin Laboratories Limited | Pharmaceutical composition for controlled release of an active ingredient |
| ATE319434T1 (de) | 2001-11-19 | 2006-03-15 | Lupin Ltd | Pharmazeutische zusammensetzung für die kontrollierte freisetzung eines beta-lactam- antibiotikums |
| CN1853724A (zh) | 2004-12-01 | 2006-11-01 | 吴晓辉 | 丙磺舒钠、钾与β－内酰胺类抗生素组成复方针剂及其用途 |
| CN1813700A (zh) | 2006-03-01 | 2006-08-09 | 吴晓辉 | 丙磺舒钠与青霉素类抗生素组成复方针剂 |
| PE20080940A1 (es) | 2006-06-28 | 2008-07-09 | Pfizer Prod Inc | Profarmacos de penem |
| ES2355950T3 (es) * | 2006-06-28 | 2011-04-01 | Pfizer Products Inc. | Profármacos de penem. |
| US20080125408A1 (en) * | 2006-11-14 | 2008-05-29 | Pfizer Inc | Penem prodrug |
| JP2016512817A (ja) | 2013-03-15 | 2016-05-09 | ヤンセン ファーマシューティカ エヌ．ベー． | 高尿酸血症の治療におけるカナグリフロジンとプロベネシドの組合せ |
| TR201605632A1 (tr) | 2016-04-28 | 2017-11-21 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Flurbi̇profen ve tramadolün yavaş salinimli kombi̇nasyonlari |
| MX2021009755A (es) | 2019-02-13 | 2021-11-17 | Iterum Therapeutics International Ltd | Combinaciones de compuestos beta-lactámicos y probenecid, y usos de los mismos. |
-
2019
- 2019-04-01 US US16/372,075 patent/US11554112B2/en active Active
- 2019-06-06 TW TW108119817A patent/TW202005970A/zh unknown
- 2019-06-07 JP JP2020568390A patent/JP2021525787A/ja active Pending
- 2019-06-07 AU AU2019281018A patent/AU2019281018A1/en active Pending
- 2019-06-07 CN CN201980052188.5A patent/CN112739338A/zh active Pending
- 2019-06-07 EP EP19733967.4A patent/EP3801486A1/en active Pending
- 2019-06-07 BR BR112020024498-8A patent/BR112020024498A2/pt unknown
- 2019-06-07 WO PCT/EP2019/065016 patent/WO2019234240A1/en unknown
-
2022
- 2022-12-13 US US18/065,400 patent/US20230218588A1/en active Pending
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