JPWO2012133349A1 - アフィニティー分離マトリックス用タンパク質 - Google Patents

アフィニティー分離マトリックス用タンパク質 Download PDF

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Publication number
JPWO2012133349A1
JPWO2012133349A1 JP2013507573A JP2013507573A JPWO2012133349A1 JP WO2012133349 A1 JPWO2012133349 A1 JP WO2012133349A1 JP 2013507573 A JP2013507573 A JP 2013507573A JP 2013507573 A JP2013507573 A JP 2013507573A JP WO2012133349 A1 JPWO2012133349 A1 JP WO2012133349A1
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JP
Japan
Prior art keywords
protein
domain
amino acid
lys
affinity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2013507573A
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English (en)
Japanese (ja)
Inventor
吉田　慎一
慎一 吉田
大 村田
大 村田
俊一 平良
俊一 平良
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kaneka Corp
Original Assignee
Kaneka Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaneka Corp filed Critical Kaneka Corp
Publication of JPWO2012133349A1 publication Critical patent/JPWO2012133349A1/ja
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G or L chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/40—Aspects relating to the composition of sorbent or filter aid materials
    • B01J2220/48—Sorbents characterised by the starting material used for their preparation
    • B01J2220/4812—Sorbents characterised by the starting material used for their preparation the starting material being of organic character
    • B01J2220/4856—Proteins, DNA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1271—Micrococcaceae (F); Staphylococcaceae (F), e.g. Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • C07K17/10—Peptides being immobilised on, or in, an organic carrier the carrier being a carbohydrate
    • C07K17/12—Cellulose or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
JP2013507573A 2011-03-25 2012-03-26 アフィニティー分離マトリックス用タンパク質 Pending JPWO2012133349A1 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2011068498 2011-03-25
JP2011068498 2011-03-25
PCT/JP2012/057824 WO2012133349A1 (ja) 2011-03-25 2012-03-26 アフィニティー分離マトリックス用タンパク質

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016217208A Division JP2017070289A (ja) 2011-03-25 2016-11-07 アフィニティー分離マトリックス用タンパク質

Publications (1)

Publication Number Publication Date
JPWO2012133349A1 true JPWO2012133349A1 (ja) 2014-07-28

Family

ID=46931066

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2013507573A Pending JPWO2012133349A1 (ja) 2011-03-25 2012-03-26 アフィニティー分離マトリックス用タンパク質
JP2016217208A Pending JP2017070289A (ja) 2011-03-25 2016-11-07 アフィニティー分離マトリックス用タンパク質

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2016217208A Pending JP2017070289A (ja) 2011-03-25 2016-11-07 アフィニティー分離マトリックス用タンパク質

Country Status (4)

Country Link
US (1) US10065995B2 (https=)
EP (1) EP2690173B1 (https=)
JP (2) JPWO2012133349A1 (https=)
WO (1) WO2012133349A1 (https=)

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EP3059252B1 (en) 2013-10-15 2018-12-05 Kaneka Corporation Production method for porous cellulose beads and absorbent employing same
US11566082B2 (en) * 2014-11-17 2023-01-31 Cytiva Bioprocess R&D Ab Mutated immunoglobulin-binding polypeptides
CN107428807A (zh) 2015-02-05 2017-12-01 三菱化学株式会社 对免疫球蛋白具有亲和性的蛋白质和使用它的亲和分离剂、液相色谱柱
JP6705806B2 (ja) * 2015-03-26 2020-06-03 Jsr株式会社 イムノグロブリン結合タンパク質およびそれを用いたアフィニティー担体
JPWO2017022672A1 (ja) * 2015-07-31 2018-07-05 株式会社カネカ 免疫グロブリン結合性改変型タンパク質
EP3333262A4 (en) * 2015-08-04 2019-04-03 Kaneka Corporation IMMUNOGLOBULIN BINDING MODIFIED PROTEINS
WO2017194593A1 (en) 2016-05-11 2017-11-16 Ge Healthcare Bioprocess R&D Ab Method of cleaning and/or sanitizing a separation matrix
US10730908B2 (en) 2016-05-11 2020-08-04 Ge Healthcare Bioprocess R&D Ab Separation method
US10889615B2 (en) 2016-05-11 2021-01-12 Cytiva Bioprocess R&D Ab Mutated immunoglobulin-binding polypeptides
US10703774B2 (en) 2016-09-30 2020-07-07 Ge Healthcare Bioprocess R&D Ab Separation method
JP7031934B2 (ja) 2016-05-11 2022-03-08 サイティバ・バイオプロセス・アールアンドディ・アクチボラグ 分離マトリックス
US10654887B2 (en) 2016-05-11 2020-05-19 Ge Healthcare Bio-Process R&D Ab Separation matrix
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CN109963864B (zh) * 2016-08-11 2024-01-02 瑞普利金公司 用于亲和色谱的碱性稳定性fc结合蛋白
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WO2018088519A1 (ja) * 2016-11-10 2018-05-17 株式会社カネカ 遺伝子導入細胞の製造方法
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US11779860B2 (en) 2017-08-07 2023-10-10 Repligen Corporation Fc binding proteins with cysteine in the C-terminal helical region
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EP3521304B9 (en) * 2018-02-01 2023-10-04 Repligen Corporation Fc binding proteins with cysteine in the c-terminal helical region
CN111315887B (zh) * 2017-11-09 2024-02-06 东曹株式会社 免疫球蛋白结合性蛋白质
WO2019187603A1 (ja) * 2018-03-29 2019-10-03 株式会社カネカ 免疫グロブリンｇ結合性ペプチド
EP3816188B1 (en) * 2018-06-29 2024-03-13 National University Corporation Kyoto Institute of Technology Separating agent
EP3816189A4 (en) * 2018-06-29 2021-09-22 National University Corporation Kyoto Institute of Technology RELEASE AGENTS
US20220213140A1 (en) * 2019-04-10 2022-07-07 Chugai Seiyaku Kabushiki Kaisha Method for purifying fc region-modified antibody
US12514914B2 (en) 2019-05-14 2026-01-06 The University Of Chicago Methods and compositions comprising Staphylococcus protein a (SpA) variants
JP7587737B2 (ja) * 2020-08-19 2024-11-21 東ソー株式会社 免疫グロブリン結合活性を有するポリペプチド
EP4563699A4 (en) * 2022-07-26 2025-11-26 Panasonic Ip Man Co Ltd ENZYMATIC ELECTRODE, ENZYMATIC REACTION DEVICE, ENZYMATIC REACTION METHOD, MODIFIED PROTEIN AND METHOD FOR PRODUCING MODIFIED PROTEIN
EP4563698A1 (en) * 2022-07-26 2025-06-04 Panasonic Intellectual Property Management Co., Ltd. Enzyme electrode, reduction device, reduction method, modified protein, and production method for modified protein
CN115850408A (zh) * 2022-09-01 2023-03-28 西安蓝晓科技新材料股份有限公司 一种多肽、融合型多聚体蛋白质及其用途
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Also Published As

Publication number Publication date
WO2012133349A1 (ja) 2012-10-04
US10065995B2 (en) 2018-09-04
EP2690173A4 (en) 2015-01-14
JP2017070289A (ja) 2017-04-13
EP2690173B1 (en) 2019-07-03
US20140107315A1 (en) 2014-04-17
EP2690173A1 (en) 2014-01-29

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