JPWO2012132768A1 - 血液成分測定装置 - Google Patents
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- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
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- A—HUMAN NECESSITIES
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- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1491—Heated applicators
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- A—HUMAN NECESSITIES
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- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4887—Locating particular structures in or on the body
- A61B5/489—Blood vessels
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/314—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
- G01N21/359—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using near infrared light
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/04—Arrangements of multiple sensors of the same type
- A61B2562/046—Arrangements of multiple sensors of the same type in a matrix array
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
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Abstract
Description
図1は、本発明の第1実施形態に係る血液成分測定装置10Aの概略構成を示す図である。この血液成分測定装置10Aは、照射光源12と、受光部14と、保持機構16と、加温機構18と、演算手段20とを備え、照射光源12から出射した光を生体の生体部位11に透過させ、透過光を受光部14で受光し、受光部14で得られた信号を演算手段20で演算・解析して、生体部位11における血液成分を測定するための医療機器である。
次に、図6を参照し、第2実施形態に係る血液成分測定装置10Bについて説明する。なお、第2実施形態に係る血液成分測定装置10Bにおいて、第1実施形態に血液成分測定装置10Aと同一又は同様な機能及び効果を奏する要素には同一の参照符号を付し、詳細な説明を省略する。
図7は、本発明の第3実施形態に係る血液成分測定装置10Cの概略構成を示す図である。この血液成分測定装置10Cは、照射光源12と、受光部14と、保持機構16と、加温機構18と、演算手段52とを備え、照射光源12から出射した光を生体の生体部位11に透過させ、透過光を受光部14で受光し、受光部14で得られた信号を演算手段52で演算・解析して、生体部位11における血液成分を測定するための医療機器である。
次に、図10を参照し、第4実施形態に係る血液成分測定装置10Dについて説明する。なお、第4実施形態に係る血液成分測定装置10Dにおいて、第3実施形態に血液成分測定装置10Cと同一又は同様な機能及び効果を奏する要素には同一の参照符号を付し、詳細な説明を省略する。
Claims (5)
- 生体部位(11)に光を照射して、前記生体部位(11)の血液成分を測定する血液成分測定装置(10A、10B、10C、10D)であって、
少なくとも近赤外域の光を出射可能な照射光源(12)と、
前記照射光源(12)で出射可能な光を受光可能な感度を持つ受光部(14、45)と、
前記生体部位(11)を保持・固定する保持機構(16)と、
前記生体部位(11)における血液成分の濃度を算出する演算手段(20、52)とを備え、
前記演算手段(20、52)は、前記生体部位(11)のうち、血色素に相対的に吸収されやすい第1の波長の透過光強度S1と、血色素に相対的に吸収されにくい第2の波長の透過光強度S2との比(S1/S2)が最小の箇所について、前記血液成分の濃度を算出する、
ことを特徴とする血液成分測定装置(10A、10B、10C、10D)。 - 請求項1記載の血液成分測定装置(10A、10C)において、
前記受光部(14)は、受光素子がマトリックス状に配置された受光素子アレイであり、
前記演算手段(20、52)は、前記受光素子アレイを構成する前記受光素子のうち、前記第1の波長の透過光強度S1と、前記第2の波長の透過光強度S2との比(S1/S2)が最小のものについて、前記血液成分の濃度を算出する、
ことを特徴とする血液成分測定装置(10A、10C)。 - 請求項1記載の血液成分測定装置(10B、10D)において、
前記照射光源(12)と前記保持機構(16)との間の光路上に、前記照射光源(12)からの光を反射して前記生体部位(11)に対して走査するスキャナ機構(44)を備え、
前記受光部(45)は、前記スキャナ機構(44)による光の走査により、前記生体部位(11)の複数箇所について、前記第1の波長の透過光と前記第2の波長の透過光をそれぞれ受光し、
前記演算手段(20、52)は、前記第1の波長の光と前記第2の波長の光が照射された前記生体部位(11)のうち、前記第1の波長の透過光強度S1と、前記第2の波長の透過光強度S2との比が最小の箇所について、前記血液成分の濃度を算出する、
ことを特徴とする血液成分測定装置(10B、10D)。 - 請求項1記載の血液成分測定装置(10C、10D)において、
前記演算手段(52)は、
前記生体部位(11)において、前記比(S1/S2)が最小の箇所を第1測定部位として抽出する第1抽出部(56)と、
前記生体部位(11)において、前記第2の波長の透過光強度S2が前記第1測定部位とほぼ等しい部位のうち前記比(S1/S2)が最大となる箇所を第2測定部位として抽出する第2抽出部(58)と、
前記第1測定部位の透過スペクトルを生成する第1透過スペクトル生成部(60)と、
前記第2測定部位の透過スペクトルを生成する第2透過スペクトル生成部(62)と、
前記第1測定部位の透過スペクトルと、前記第2測定部位の透過スペクトルとから、前記第1測定部位と前記第2測定部位との差分透過スペクトルを演算する差分透過スペクトル算出部(64)と、
前記差分透過スペクトルに基づいて、前記血液成分の濃度を算出する濃度算出部(38)とを有する、
ことを特徴とする血液成分測定装置(10C、10D)。 - 請求項1記載の血液成分測定装置(10A、10B、10C、10D)において、
前記生体部位(11)を加温する加温機構を備える、
ことを特徴とする血液成分測定装置(10A、10B、10C、10D)。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2011078079 | 2011-03-31 | ||
JP2011078079 | 2011-03-31 | ||
PCT/JP2012/055520 WO2012132768A1 (ja) | 2011-03-31 | 2012-03-05 | 血液成分測定装置 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPWO2012132768A1 true JPWO2012132768A1 (ja) | 2014-07-28 |
JP5990508B2 JP5990508B2 (ja) | 2016-09-14 |
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JP2013507311A Active JP5990508B2 (ja) | 2011-03-31 | 2012-03-05 | 血液成分測定装置 |
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US (1) | US20140024904A1 (ja) |
JP (1) | JP5990508B2 (ja) |
CN (1) | CN103429154B (ja) |
HK (1) | HK1189784A1 (ja) |
WO (1) | WO2012132768A1 (ja) |
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JP6428052B2 (ja) * | 2014-08-26 | 2018-11-28 | セイコーエプソン株式会社 | 生体情報取得装置及び電子機器 |
WO2016069909A1 (en) | 2014-10-29 | 2016-05-06 | Zoll Medical Corporation | Transesophageal or transtracheal cardiac monitoring by optical spectroscopy |
CN104490403B (zh) * | 2014-12-06 | 2016-08-17 | 深圳市贝沃德克生物技术研究院有限公司 | 基于光谱技术的无创血糖测量系统及其测量方法 |
US10716499B1 (en) | 2015-03-24 | 2020-07-21 | Zoll Medical Corporation | Physiological monitoring by optical spectroscopy |
US11432748B2 (en) * | 2016-06-28 | 2022-09-06 | Roxanne Abul-Haj | Common depth noninvasive glucose concentration determination analyzer apparatus and method of use thereof |
CN205958453U (zh) * | 2016-08-19 | 2017-02-15 | 深圳市前海康启源科技有限公司 | 葡萄糖浓度检测装置 |
JP7155109B2 (ja) * | 2017-03-23 | 2022-10-18 | テルモ株式会社 | 成分測定装置及び成分測定装置セット |
WO2018194056A1 (ja) * | 2017-04-18 | 2018-10-25 | 興和株式会社 | 血液の吸収スペクトルを算出する情報処理方法、情報処理装置およびプログラム |
TWI633618B (zh) * | 2017-08-02 | 2018-08-21 | 李美燕 | 積體化微型夾持器、其製造方法以及使用其之積體化微型夾持器陣列及轉移系統 |
CN107969905B (zh) * | 2017-12-22 | 2020-05-05 | 浙江浩鑫家庭用品有限公司 | 一种智能炖锅 |
CN108041972B (zh) * | 2017-12-22 | 2020-06-26 | 福州盛世凌云环保科技有限公司 | 一种有助于血脂保健的炖锅 |
CN107981706B (zh) * | 2017-12-22 | 2020-06-26 | 福州盛世凌云环保科技有限公司 | 一种炖锅 |
US11313788B2 (en) * | 2018-06-15 | 2022-04-26 | Genial Light Co., Ltd. | Body fluid analysis device |
CN110584678B (zh) * | 2019-09-06 | 2024-05-10 | 广东宝莱特医用科技股份有限公司 | 一种血容量变化率的测量方法和装置 |
TW202237032A (zh) * | 2021-02-19 | 2022-10-01 | 日商日本瑞翁股份有限公司 | 活體資訊量測裝置 |
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JP3701031B2 (ja) * | 1995-12-27 | 2005-09-28 | シスメックス株式会社 | 非侵襲血液検査装置 |
US5974338A (en) * | 1997-04-15 | 1999-10-26 | Toa Medical Electronics Co., Ltd. | Non-invasive blood analyzer |
JP4072240B2 (ja) * | 1997-04-15 | 2008-04-09 | シスメックス株式会社 | 非侵襲血液分析装置 |
US6675031B1 (en) * | 1999-04-14 | 2004-01-06 | Mallinckrodt Inc. | Method and circuit for indicating quality and accuracy of physiological measurements |
US6975891B2 (en) * | 2001-12-21 | 2005-12-13 | Nir Diagnostics Inc. | Raman spectroscopic system with integrating cavity |
US8175666B2 (en) * | 2002-04-26 | 2012-05-08 | Grove Instruments, Inc. | Three diode optical bridge system |
WO2006098281A1 (ja) * | 2005-03-16 | 2006-09-21 | Matsushita Electric Industrial Co., Ltd. | 画像投影装置 |
WO2006126152A1 (en) * | 2005-05-24 | 2006-11-30 | Koninklijke Philips Electronics N.V. | Glucose sensor |
JP2009153621A (ja) * | 2007-12-25 | 2009-07-16 | Olympus Corp | 生体観察装置および内視鏡装置 |
-
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- 2012-03-05 JP JP2013507311A patent/JP5990508B2/ja active Active
- 2012-03-05 WO PCT/JP2012/055520 patent/WO2012132768A1/ja active Application Filing
- 2012-03-05 CN CN201280011816.3A patent/CN103429154B/zh active Active
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2013
- 2013-09-24 US US14/035,072 patent/US20140024904A1/en not_active Abandoned
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- 2014-03-25 HK HK14102939.4A patent/HK1189784A1/xx unknown
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CN103429154A (zh) | 2013-12-04 |
US20140024904A1 (en) | 2014-01-23 |
WO2012132768A1 (ja) | 2012-10-04 |
JP5990508B2 (ja) | 2016-09-14 |
CN103429154B (zh) | 2015-10-21 |
HK1189784A1 (en) | 2014-06-20 |
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