JPS6456666A - Cyclopropylmethoxy-2-mercaptobenzimidazole and production thereof - Google Patents
Cyclopropylmethoxy-2-mercaptobenzimidazole and production thereofInfo
- Publication number
- JPS6456666A JPS6456666A JP21267187A JP21267187A JPS6456666A JP S6456666 A JPS6456666 A JP S6456666A JP 21267187 A JP21267187 A JP 21267187A JP 21267187 A JP21267187 A JP 21267187A JP S6456666 A JPS6456666 A JP S6456666A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- cyclopropylmethoxy
- benzimidazole derivative
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:Cyclopropylmethoxy-2-mercaptobenzmidazole of formula I. USE:Useful as a production intermediate for a benzimidazole derivative which is a novel antiulcer compound. The benzimidazole derivative of formula II can be synthesized by condensing the compound of formula I with a pyridine compound and oxidizing the condensation product. The compound of formula II is an excellent drug having sufficiently high storage stability and exhibiting excellent gastric acid secretion inhibitory action caused by the inhibition of potassium ion-dependent adenosine triphosphatase activity. PREPARATION:The compound of formula I can be produced by reducing cyclopropylmethoxy-1,2-dinitrobenzene of formula III and reacting the resultant cyclopropylmethoxy-o-phenylenediamine with potassium ethylxanthogenate or carbon dioxide.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62212671A JP2546850B2 (en) | 1987-08-28 | 1987-08-28 | Cyclopropylmethoxy-2-mercaptobenzimidazole and process for producing the same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62212671A JP2546850B2 (en) | 1987-08-28 | 1987-08-28 | Cyclopropylmethoxy-2-mercaptobenzimidazole and process for producing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS6456666A true JPS6456666A (en) | 1989-03-03 |
JP2546850B2 JP2546850B2 (en) | 1996-10-23 |
Family
ID=16626472
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP62212671A Expired - Lifetime JP2546850B2 (en) | 1987-08-28 | 1987-08-28 | Cyclopropylmethoxy-2-mercaptobenzimidazole and process for producing the same |
Country Status (1)
Country | Link |
---|---|
JP (1) | JP2546850B2 (en) |
-
1987
- 1987-08-28 JP JP62212671A patent/JP2546850B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP2546850B2 (en) | 1996-10-23 |
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