JPS6456666A - Cyclopropylmethoxy-2-mercaptobenzimidazole and production thereof - Google Patents

Cyclopropylmethoxy-2-mercaptobenzimidazole and production thereof

Info

Publication number
JPS6456666A
JPS6456666A JP21267187A JP21267187A JPS6456666A JP S6456666 A JPS6456666 A JP S6456666A JP 21267187 A JP21267187 A JP 21267187A JP 21267187 A JP21267187 A JP 21267187A JP S6456666 A JPS6456666 A JP S6456666A
Authority
JP
Japan
Prior art keywords
formula
compound
cyclopropylmethoxy
benzimidazole derivative
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP21267187A
Other languages
Japanese (ja)
Other versions
JP2546850B2 (en
Inventor
Haruki Takeda
Kenichi Iiizumi
Masazumi Tomari
Shinji Tsuchiya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tokyo Tanabe Co Ltd
Original Assignee
Tokyo Tanabe Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tokyo Tanabe Co Ltd filed Critical Tokyo Tanabe Co Ltd
Priority to JP62212671A priority Critical patent/JP2546850B2/en
Publication of JPS6456666A publication Critical patent/JPS6456666A/en
Application granted granted Critical
Publication of JP2546850B2 publication Critical patent/JP2546850B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Abstract

NEW MATERIAL:Cyclopropylmethoxy-2-mercaptobenzmidazole of formula I. USE:Useful as a production intermediate for a benzimidazole derivative which is a novel antiulcer compound. The benzimidazole derivative of formula II can be synthesized by condensing the compound of formula I with a pyridine compound and oxidizing the condensation product. The compound of formula II is an excellent drug having sufficiently high storage stability and exhibiting excellent gastric acid secretion inhibitory action caused by the inhibition of potassium ion-dependent adenosine triphosphatase activity. PREPARATION:The compound of formula I can be produced by reducing cyclopropylmethoxy-1,2-dinitrobenzene of formula III and reacting the resultant cyclopropylmethoxy-o-phenylenediamine with potassium ethylxanthogenate or carbon dioxide.
JP62212671A 1987-08-28 1987-08-28 Cyclopropylmethoxy-2-mercaptobenzimidazole and process for producing the same Expired - Lifetime JP2546850B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62212671A JP2546850B2 (en) 1987-08-28 1987-08-28 Cyclopropylmethoxy-2-mercaptobenzimidazole and process for producing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62212671A JP2546850B2 (en) 1987-08-28 1987-08-28 Cyclopropylmethoxy-2-mercaptobenzimidazole and process for producing the same

Publications (2)

Publication Number Publication Date
JPS6456666A true JPS6456666A (en) 1989-03-03
JP2546850B2 JP2546850B2 (en) 1996-10-23

Family

ID=16626472

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62212671A Expired - Lifetime JP2546850B2 (en) 1987-08-28 1987-08-28 Cyclopropylmethoxy-2-mercaptobenzimidazole and process for producing the same

Country Status (1)

Country Link
JP (1) JP2546850B2 (en)

Also Published As

Publication number Publication date
JP2546850B2 (en) 1996-10-23

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