JPS5461128A - Peptide derivative - Google Patents
Peptide derivativeInfo
- Publication number
- JPS5461128A JPS5461128A JP12469177A JP12469177A JPS5461128A JP S5461128 A JPS5461128 A JP S5461128A JP 12469177 A JP12469177 A JP 12469177A JP 12469177 A JP12469177 A JP 12469177A JP S5461128 A JPS5461128 A JP S5461128A
- Authority
- JP
- Japan
- Prior art keywords
- arginine
- formula
- nitroanilide
- peptide derivative
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Abstract
NEW MATERIAL:Peptide derivative of formula and its acid addition salt (R is serylglycyl, leucylglycyl, glutarylglycyl, tert-alkyloxycarbonylglycyl, valylprolyl or ter-alkyloxycarbonylprolyl).
EXAMPLE: t-Butyloxycarbonyl-glycyl-L-arginine-p-nitroanilide derivative.
USE: Useful as a synthetic substrate having specificity to enzymes such as trpsin, kallikrein, thrombin, urokinase, etc.
PROCESS: The title compound of formula is prepared e.g. by reacting L-arginine- p-nitroanilide di-hydrochloride with t-butyloxycarbonylglycine-N-hydroxysuccinimide ester in a solvent, followed by eliminating the amino- or OH-protecting groups.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP52124691A JPS5919532B2 (en) | 1977-10-18 | 1977-10-18 | peptide derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP52124691A JPS5919532B2 (en) | 1977-10-18 | 1977-10-18 | peptide derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5461128A true JPS5461128A (en) | 1979-05-17 |
JPS5919532B2 JPS5919532B2 (en) | 1984-05-07 |
Family
ID=14891695
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP52124691A Expired JPS5919532B2 (en) | 1977-10-18 | 1977-10-18 | peptide derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5919532B2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6061557A (en) * | 1983-09-14 | 1985-04-09 | Nitto Boseki Co Ltd | Production of arginyl-p-nitroanilide |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8546072B2 (en) | 2008-02-22 | 2013-10-01 | Wako Pure Chemical Industries, Ltd. | Substrate for assaying β-glucan and/or endotoxin and assay method |
-
1977
- 1977-10-18 JP JP52124691A patent/JPS5919532B2/en not_active Expired
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6061557A (en) * | 1983-09-14 | 1985-04-09 | Nitto Boseki Co Ltd | Production of arginyl-p-nitroanilide |
JPS6332348B2 (en) * | 1983-09-14 | 1988-06-29 | Nitto Boseki Co Ltd |
Also Published As
Publication number | Publication date |
---|---|
JPS5919532B2 (en) | 1984-05-07 |
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