FR2350341A1 - (4)-Benzyl piperidine derivs. useful as intermediates - e.g. (3,4)-methylenedioxy-benzyl-piperidine - Google Patents

(4)-Benzyl piperidine derivs. useful as intermediates - e.g. (3,4)-methylenedioxy-benzyl-piperidine

Info

Publication number
FR2350341A1
FR2350341A1 FR7613682A FR7613682A FR2350341A1 FR 2350341 A1 FR2350341 A1 FR 2350341A1 FR 7613682 A FR7613682 A FR 7613682A FR 7613682 A FR7613682 A FR 7613682A FR 2350341 A1 FR2350341 A1 FR 2350341A1
Authority
FR
France
Prior art keywords
piperidine
benzyl
derivs
methylenedioxy
intermediates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7613682A
Other languages
French (fr)
Other versions
FR2350341B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR7613682A priority Critical patent/FR2350341A1/en
Publication of FR2350341A1 publication Critical patent/FR2350341A1/en
Application granted granted Critical
Publication of FR2350341B1 publication Critical patent/FR2350341B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms

Abstract

Piperidine derivs. of formula (I) and acid addition salts are new: - (where x is -CH2-, -CHOH- or -CO-; and (i) R1-3 are all OCH3, or(ii) R1 is H and R2 and R3 together form -OCH2O-bonded to adjacent C atoms of the benzene ring). (I) are synthetic intermediates used in prepn. of e.g. pharmacologically active piperidines. In an example, 3,4-methylenedioxyphenyl-(4-piperidyl)carbinol was prepd.
FR7613682A 1976-05-07 1976-05-07 (4)-Benzyl piperidine derivs. useful as intermediates - e.g. (3,4)-methylenedioxy-benzyl-piperidine Granted FR2350341A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7613682A FR2350341A1 (en) 1976-05-07 1976-05-07 (4)-Benzyl piperidine derivs. useful as intermediates - e.g. (3,4)-methylenedioxy-benzyl-piperidine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7613682A FR2350341A1 (en) 1976-05-07 1976-05-07 (4)-Benzyl piperidine derivs. useful as intermediates - e.g. (3,4)-methylenedioxy-benzyl-piperidine

Publications (2)

Publication Number Publication Date
FR2350341A1 true FR2350341A1 (en) 1977-12-02
FR2350341B1 FR2350341B1 (en) 1980-05-23

Family

ID=9172813

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7613682A Granted FR2350341A1 (en) 1976-05-07 1976-05-07 (4)-Benzyl piperidine derivs. useful as intermediates - e.g. (3,4)-methylenedioxy-benzyl-piperidine

Country Status (1)

Country Link
FR (1) FR2350341A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994000432A1 (en) * 1992-06-30 1994-01-06 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Anorectic epinephrine derivatives
US6713627B2 (en) 1998-03-13 2004-03-30 Aventis Pharmaceuticals Inc. Processes for the preparation of (R)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
WO2008045564A2 (en) * 2006-10-12 2008-04-17 Epix Delaware, Inc. Carboxamide compounds and their use as antagonists of the chemokine ccr2 receptor

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8569282B2 (en) 2007-12-11 2013-10-29 Cytopathfinder, Inc. Carboxamide compounds and their use

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994000432A1 (en) * 1992-06-30 1994-01-06 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Anorectic epinephrine derivatives
US6713627B2 (en) 1998-03-13 2004-03-30 Aventis Pharmaceuticals Inc. Processes for the preparation of (R)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
US7332607B2 (en) 1998-03-13 2008-02-19 Aventis Holdings Inc. Processes for the preparation of (R)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
WO2008045564A2 (en) * 2006-10-12 2008-04-17 Epix Delaware, Inc. Carboxamide compounds and their use as antagonists of the chemokine ccr2 receptor
WO2008045564A3 (en) * 2006-10-12 2008-05-29 Epix Delaware Inc Carboxamide compounds and their use as antagonists of the chemokine ccr2 receptor

Also Published As

Publication number Publication date
FR2350341B1 (en) 1980-05-23

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Legal Events

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