JPS64394B2 - - Google Patents

Info

Publication number
JPS64394B2
JPS64394B2 JP53046785A JP4678578A JPS64394B2 JP S64394 B2 JPS64394 B2 JP S64394B2 JP 53046785 A JP53046785 A JP 53046785A JP 4678578 A JP4678578 A JP 4678578A JP S64394 B2 JPS64394 B2 JP S64394B2
Authority
JP
Japan
Prior art keywords
compound
hydrochloride
compound according
dihydroisoquinoline
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP53046785A
Other languages
English (en)
Japanese (ja)
Other versions
JPS54141786A (en
Inventor
Baanaado Ru Hooru Jan
Marutan Mitsusheru
Nadoreeru Guai
Saiasu Edomondo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RABO SOBIO SA
Original Assignee
RABO SOBIO SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RABO SOBIO SA filed Critical RABO SOBIO SA
Publication of JPS54141786A publication Critical patent/JPS54141786A/ja
Publication of JPS64394B2 publication Critical patent/JPS64394B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
JP4678578A 1976-10-21 1978-04-20 Hydrogenated benzylisoquinoline derivatives* their manufacture*medical composition containing them and intermediate compounds for their manufacture Granted JPS54141786A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7631658A FR2368277A1 (fr) 1976-10-21 1976-10-21 Nouveaux derives hydrogenes de l'isoquinoleine, ayant une activite vasoactive et spasmolytique

Publications (2)

Publication Number Publication Date
JPS54141786A JPS54141786A (en) 1979-11-05
JPS64394B2 true JPS64394B2 (OSRAM) 1989-01-06

Family

ID=9179024

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4678578A Granted JPS54141786A (en) 1976-10-21 1978-04-20 Hydrogenated benzylisoquinoline derivatives* their manufacture*medical composition containing them and intermediate compounds for their manufacture

Country Status (8)

Country Link
US (1) US4442108A (OSRAM)
JP (1) JPS54141786A (OSRAM)
AT (1) AT356110B (OSRAM)
BE (1) BE866208A (OSRAM)
CH (1) CH642632A5 (OSRAM)
DE (1) DE2817083A1 (OSRAM)
FR (1) FR2368277A1 (OSRAM)
NL (1) NL7804202A (OSRAM)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU183479B (en) * 1981-06-16 1984-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing new 6,7-diethoxy-1-aracket-4-ethoxy-3-hydroxy-benzyl-bracket closed-3,4-dihydroisoquinolin
DE3338681A1 (de) * 1983-10-25 1985-05-09 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von n-methylhomoveratrylamin
US4956371A (en) * 1989-09-19 1990-09-11 Euroceltique, S.A. Substituted isoquinolines and methods of using same
JPH06247935A (ja) * 1993-02-25 1994-09-06 Banyu Pharmaceut Co Ltd ６，７−ジアルコキシ−３，４−ジヒドロイソキノリン−８−オール類、その製造法及び該化合物を用いた６，７−ジアルコキシ−１，２，３，４−テトラヒドロイソキノリン−８−オール類の製造法
WO1999016752A1 (en) * 1997-09-30 1999-04-08 Molecular Designs International, Inc. β3-ADRENORECEPTOR AGONISTS, AGONIST COMPOSITIONS AND METHODS OF USING
US6846492B2 (en) 2000-02-23 2005-01-25 Ciba Specialty Chemicals Corporation Use of phenylethylamine derivatives for the antimicrobial treatment of surfaces
DE60118348T2 (de) * 2000-02-23 2006-08-24 Ciba Speciality Chemicals Holding Inc. Verwendung von phenylethylaminderivaten zur antimikrobiellen behandlung von oberflächen
US6593341B2 (en) 2001-03-29 2003-07-15 Molecular Design International, Inc. β3-adrenoreceptor agonists, agonist compositions and methods of making and using the same
US6596734B1 (en) 2002-10-11 2003-07-22 Molecular Design International, Inc. Tetrahydroisoquinoline compounds for use as β3-adrenoreceptor agonists

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2928769A (en) * 1957-07-22 1960-03-15 Strong Cobb And Company Inc Production of controlled release medicaments
IL33480A (en) * 1968-12-10 1973-03-30 Tanabe Seiyaku Co 6,7-diacyloxy-tetrahydro-isoquinolines and their preparation
HU167246B (OSRAM) * 1973-01-25 1975-09-27
JPS5734275B2 (OSRAM) * 1973-07-30 1982-07-22

Also Published As

Publication number Publication date
FR2368277B1 (OSRAM) 1979-02-23
NL7804202A (nl) 1979-10-23
ATA284478A (de) 1979-09-15
JPS54141786A (en) 1979-11-05
US4442108A (en) 1984-04-10
AT356110B (de) 1980-04-10
CH642632A5 (de) 1984-04-30
BE866208A (fr) 1978-10-20
FR2368277A1 (fr) 1978-05-19
DE2817083A1 (de) 1979-11-15

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