CH642632A5 - Benzylisochinolin-derivate, verfahren zu ihrer herstellung und die verwendung dieser verbindungen in arzneipraeparaten. - Google Patents

Benzylisochinolin-derivate, verfahren zu ihrer herstellung und die verwendung dieser verbindungen in arzneipraeparaten. Download PDF

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Publication number
CH642632A5
CH642632A5 CH425478A CH425478A CH642632A5 CH 642632 A5 CH642632 A5 CH 642632A5 CH 425478 A CH425478 A CH 425478A CH 425478 A CH425478 A CH 425478A CH 642632 A5 CH642632 A5 CH 642632A5
Authority
CH
Switzerland
Prior art keywords
hydrochloride
formula
compounds
acid addition
compound
Prior art date
Application number
CH425478A
Other languages
German (de)
English (en)
Inventor
Jean-Bernard Le Polles
Michel Martin
Guy Nadler
Edmond Saias
Original Assignee
Sobio Laboratoires Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sobio Laboratoires Sa filed Critical Sobio Laboratoires Sa
Publication of CH642632A5 publication Critical patent/CH642632A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
CH425478A 1976-10-21 1978-04-20 Benzylisochinolin-derivate, verfahren zu ihrer herstellung und die verwendung dieser verbindungen in arzneipraeparaten. CH642632A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7631658A FR2368277A1 (fr) 1976-10-21 1976-10-21 Nouveaux derives hydrogenes de l'isoquinoleine, ayant une activite vasoactive et spasmolytique

Publications (1)

Publication Number Publication Date
CH642632A5 true CH642632A5 (de) 1984-04-30

Family

ID=9179024

Family Applications (1)

Application Number Title Priority Date Filing Date
CH425478A CH642632A5 (de) 1976-10-21 1978-04-20 Benzylisochinolin-derivate, verfahren zu ihrer herstellung und die verwendung dieser verbindungen in arzneipraeparaten.

Country Status (8)

Country Link
US (1) US4442108A (OSRAM)
JP (1) JPS54141786A (OSRAM)
AT (1) AT356110B (OSRAM)
BE (1) BE866208A (OSRAM)
CH (1) CH642632A5 (OSRAM)
DE (1) DE2817083A1 (OSRAM)
FR (1) FR2368277A1 (OSRAM)
NL (1) NL7804202A (OSRAM)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU183479B (en) * 1981-06-16 1984-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing new 6,7-diethoxy-1-aracket-4-ethoxy-3-hydroxy-benzyl-bracket closed-3,4-dihydroisoquinolin
DE3338681A1 (de) * 1983-10-25 1985-05-09 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von n-methylhomoveratrylamin
US4956371A (en) * 1989-09-19 1990-09-11 Euroceltique, S.A. Substituted isoquinolines and methods of using same
JPH06247935A (ja) * 1993-02-25 1994-09-06 Banyu Pharmaceut Co Ltd ６，７−ジアルコキシ−３，４−ジヒドロイソキノリン−８−オール類、その製造法及び該化合物を用いた６，７−ジアルコキシ−１，２，３，４−テトラヒドロイソキノリン−８−オール類の製造法
WO1999016752A1 (en) * 1997-09-30 1999-04-08 Molecular Designs International, Inc. β3-ADRENORECEPTOR AGONISTS, AGONIST COMPOSITIONS AND METHODS OF USING
US6846492B2 (en) 2000-02-23 2005-01-25 Ciba Specialty Chemicals Corporation Use of phenylethylamine derivatives for the antimicrobial treatment of surfaces
DE60118348T2 (de) * 2000-02-23 2006-08-24 Ciba Speciality Chemicals Holding Inc. Verwendung von phenylethylaminderivaten zur antimikrobiellen behandlung von oberflächen
US6593341B2 (en) 2001-03-29 2003-07-15 Molecular Design International, Inc. β3-adrenoreceptor agonists, agonist compositions and methods of making and using the same
US6596734B1 (en) 2002-10-11 2003-07-22 Molecular Design International, Inc. Tetrahydroisoquinoline compounds for use as β3-adrenoreceptor agonists

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2928769A (en) * 1957-07-22 1960-03-15 Strong Cobb And Company Inc Production of controlled release medicaments
IL33480A (en) * 1968-12-10 1973-03-30 Tanabe Seiyaku Co 6,7-diacyloxy-tetrahydro-isoquinolines and their preparation
HU167246B (OSRAM) * 1973-01-25 1975-09-27
JPS5734275B2 (OSRAM) * 1973-07-30 1982-07-22

Also Published As

Publication number Publication date
FR2368277B1 (OSRAM) 1979-02-23
NL7804202A (nl) 1979-10-23
ATA284478A (de) 1979-09-15
JPS54141786A (en) 1979-11-05
US4442108A (en) 1984-04-10
JPS64394B2 (OSRAM) 1989-01-06
AT356110B (de) 1980-04-10
BE866208A (fr) 1978-10-20
FR2368277A1 (fr) 1978-05-19
DE2817083A1 (de) 1979-11-15

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PL Patent ceased