JPS6411026B2 - - Google Patents

Info

Publication number
JPS6411026B2
JPS6411026B2 JP55159016A JP15901680A JPS6411026B2 JP S6411026 B2 JPS6411026 B2 JP S6411026B2 JP 55159016 A JP55159016 A JP 55159016A JP 15901680 A JP15901680 A JP 15901680A JP S6411026 B2 JPS6411026 B2 JP S6411026B2
Authority
JP
Japan
Prior art keywords
dihydrocarbostyryl
imidazo
compound
pyridin
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP55159016A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5782390A (en
Inventor
Michiaki Tominaga
Nagao Yo
Hidenori Ogawa
Kazuyuki Nakagawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to JP55159016A priority Critical patent/JPS5782390A/ja
Priority to CA000389034A priority patent/CA1164459A/en
Priority to PH26478A priority patent/PH17158A/en
Priority to PT73959A priority patent/PT73959B/pt
Priority to ZA817773A priority patent/ZA817773B/xx
Priority to US06/403,582 priority patent/US4414390A/en
Priority to ES507545A priority patent/ES507545A0/es
Priority to DE813152512T priority patent/DE3152512T1/de
Priority to EP81305344A priority patent/EP0052016B1/en
Priority to PCT/JP1981/000328 priority patent/WO1982001706A1/ja
Priority to AU78085/81A priority patent/AU547586B2/en
Priority to NL8120433A priority patent/NL192040C/nl
Priority to MX819760U priority patent/MX6802E/es
Priority to CH4324/82A priority patent/CH653684A5/fr
Priority to IT8149680A priority patent/IT8149680A0/it
Priority to KR1019810004359A priority patent/KR880001657B1/ko
Priority to AT0908381A priority patent/AT382376B/de
Publication of JPS5782390A publication Critical patent/JPS5782390A/ja
Priority to SE8204237A priority patent/SE440653B/sv
Priority to DK307482A priority patent/DK157193C/da
Priority to NO82822391A priority patent/NO157819C/no
Priority to SU823466402A priority patent/SU1215621A3/ru
Priority to FI822471A priority patent/FI71145C/fi
Publication of JPS6411026B2 publication Critical patent/JPS6411026B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C07D215/28—Alcohols; Ethers thereof with halogen atoms or nitro radicals in positions 5, 6 or 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C07D215/32—Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP55159016A 1980-11-11 1980-11-11 Carbostyril derivative Granted JPS5782390A (en)

Priority Applications (22)

Application Number Priority Date Filing Date Title
JP55159016A JPS5782390A (en) 1980-11-11 1980-11-11 Carbostyril derivative
CA000389034A CA1164459A (en) 1980-11-11 1981-10-29 Process for preparing (imidazo¬1,2-a|pyridine- 2-yl)-carbostyril or -3,4-dihydrocarbostyryl derivatives
PH26478A PH17158A (en) 1980-11-11 1981-11-10 Imidazo(1,2-a)pyridin-2-yl carbostyril derivatives and compositions containing same
PT73959A PT73959B (en) 1980-11-11 1981-11-10 Process for preparing carbostyril compounds and pharmaceutical compositions containing the same
ZA817773A ZA817773B (en) 1980-11-11 1981-11-10 Carbostyril compounds,compositions containing same and processes for preparing same
NL8120433A NL192040C (nl) 1980-11-11 1981-11-11 Carbostyrilverbindingen en preparaat dat een dergelijke verbinding bevat.
IT8149680A IT8149680A0 (it) 1980-11-11 1981-11-11 Composti carbostirilici composizioni che li contengono e procedimenti per prepararli
DE813152512T DE3152512T1 (de) 1980-11-11 1981-11-11 Carbostyril compounds,composition containing same,and process for their preparation
EP81305344A EP0052016B1 (en) 1980-11-11 1981-11-11 Carbostyril compounds, compositions containing same and processes for preparing same
PCT/JP1981/000328 WO1982001706A1 (en) 1980-11-11 1981-11-11 Carbostyril compounds,composition containing same,and process for their preparation
AU78085/81A AU547586B2 (en) 1980-11-11 1981-11-11 Carbostyril compounds,composition containing same,and processfor their preparation
US06/403,582 US4414390A (en) 1980-11-11 1981-11-11 Carbostyril compounds and compositions containing same
MX819760U MX6802E (es) 1980-11-11 1981-11-11 Procedimiento para la preparacion de derivados carboestirilicos
CH4324/82A CH653684A5 (fr) 1980-11-11 1981-11-11 Derives de carbostyrile, procede pour leur preparation et compositions les contenant.
ES507545A ES507545A0 (es) 1980-11-11 1981-11-11 Procedimiento de preparar compuestos carbostirilicos.
KR1019810004359A KR880001657B1 (ko) 1980-11-11 1981-11-11 카보스티릴 화합물의 제조방법
AT0908381A AT382376B (de) 1980-11-11 1981-11-11 Verfahren zur herstellung von neuen carbostyrilverbindungen und deren pharmazeutisch annehmbaren salzen
SE8204237A SE440653B (sv) 1980-11-11 1982-07-08 Karbostyrilforeningar
DK307482A DK157193C (da) 1980-11-11 1982-07-08 Analogifremgangsmaade til fremstilling af carbostyrilforbindelser
NO82822391A NO157819C (no) 1980-11-11 1982-07-09 Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazo (1,2-a)-pyridin-2-yl-karbostyrilforbindelser.
SU823466402A SU1215621A3 (ru) 1980-11-11 1982-07-11 Способ получени карбостирильных производных или их фармацевтически приемлемых солей
FI822471A FI71145C (fi) 1980-11-11 1982-07-12 Foerfarande foer framstaellning av imidazo/1,2-a/-pyridin-2-yl-karbostyrilderivat vilka aer anvaendbara som hjaertmedicin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55159016A JPS5782390A (en) 1980-11-11 1980-11-11 Carbostyril derivative

Publications (2)

Publication Number Publication Date
JPS5782390A JPS5782390A (en) 1982-05-22
JPS6411026B2 true JPS6411026B2 (en, 2012) 1989-02-23

Family

ID=15684401

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55159016A Granted JPS5782390A (en) 1980-11-11 1980-11-11 Carbostyril derivative

Country Status (3)

Country Link
JP (1) JPS5782390A (en, 2012)
NL (1) NL192040C (en, 2012)
ZA (1) ZA817773B (en, 2012)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8305245D0 (en) * 1983-02-25 1983-03-30 Fujisawa Pharmaceutical Co Imidazo-heterocyclic compounds
GB8709448D0 (en) * 1987-04-21 1987-05-28 Pfizer Ltd Heterobicyclic quinoline derivatives

Also Published As

Publication number Publication date
ZA817773B (en) 1982-10-27
NL192040C (nl) 1997-01-07
NL8120433A (nl) 1982-10-01
JPS5782390A (en) 1982-05-22
NL192040B (nl) 1996-09-02

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