JPS6348277A - ８−ピペラジニル−１，７−ナフチリジン誘導体 - Google Patents

８−ピペラジニル−１，７−ナフチリジン誘導体

Info

Publication number
JPS6348277A
JPS6348277A JP61193095A JP19309586A JPS6348277A JP S6348277 A JPS6348277 A JP S6348277A JP 61193095 A JP61193095 A JP 61193095A JP 19309586 A JP19309586 A JP 19309586A JP S6348277 A JPS6348277 A JP S6348277A
Authority
JP
Japan
Prior art keywords
formula
naphthyridine
group
piperazinyl
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP61193095A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0432074B2 (Direct
Inventor
Haruyoshi Honda
本田　晴義
Hiroko Yoshida
裕子 吉田
Tadayuki Koda
忠行 好田
Hideaki Matsuda
松田　秀明
Tatsuhiko Katori
香取　達彦
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SSP Co Ltd
Original Assignee
SSP Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SSP Co Ltd filed Critical SSP Co Ltd
Priority to JP61193095A priority Critical patent/JPS6348277A/ja
Priority to US07/084,836 priority patent/US4866176A/en
Priority to CA000544669A priority patent/CA1300630C/en
Priority to EP87111986A priority patent/EP0256556A1/en
Publication of JPS6348277A publication Critical patent/JPS6348277A/ja
Publication of JPH0432074B2 publication Critical patent/JPH0432074B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP61193095A 1986-08-19 1986-08-19 ８−ピペラジニル−１，７−ナフチリジン誘導体 Granted JPS6348277A (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP61193095A JPS6348277A (ja) 1986-08-19 1986-08-19 ８−ピペラジニル−１，７−ナフチリジン誘導体
US07/084,836 US4866176A (en) 1986-08-19 1987-08-13 8-Piperazinyl-1,7-naphthyridine derivative having pharmaceutical activity
CA000544669A CA1300630C (en) 1986-08-19 1987-08-17 8-piperazinyl-1, 7-naphthyridine derivative
EP87111986A EP0256556A1 (en) 1986-08-19 1987-08-18 8-Piperazinyl-1,7-naphthyridine derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP61193095A JPS6348277A (ja) 1986-08-19 1986-08-19 ８−ピペラジニル−１，７−ナフチリジン誘導体

Publications (2)

Publication Number Publication Date
JPS6348277A true JPS6348277A (ja) 1988-02-29
JPH0432074B2 JPH0432074B2 (Direct) 1992-05-28

Family

ID=16302149

Family Applications (1)

Application Number Title Priority Date Filing Date
JP61193095A Granted JPS6348277A (ja) 1986-08-19 1986-08-19 ８−ピペラジニル−１，７−ナフチリジン誘導体

Country Status (4)

Country Link
US (1) US4866176A (Direct)
EP (1) EP0256556A1 (Direct)
JP (1) JPS6348277A (Direct)
CA (1) CA1300630C (Direct)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5750529A (en) * 1991-07-03 1998-05-12 Otsuka Pharmaceutical Co., Ltd. Apoptosis regulating compostion
GB9622386D0 (en) * 1996-10-28 1997-01-08 Sandoz Ltd Organic compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3429887A (en) * 1965-01-26 1969-02-25 Sterling Drug Inc 1,7-naphthyridine-3-carboxylic acid derivatives and their preparation
US3928367A (en) * 1969-04-14 1975-12-23 Schering Corp 1-Amino naphthyridines
US4168311A (en) * 1973-12-10 1979-09-18 Hoechst Aktiengesellschaft Hydroxyquinoline carbamates and n-oxide hydroxyquinoline carbamates and their use as insecticides
US4176183A (en) * 1977-05-02 1979-11-27 Merck & Co., Inc. Novel naphthyridines
US4716170A (en) * 1985-01-28 1987-12-29 Sterling Drug Inc. 5-[1H-(5-membered-N-aromatic heteryl)-1-yl]-1,6-naphthyridin-2(1H)-ones and their cardiotonic use
JPS6230780A (ja) * 1985-04-17 1987-02-09 Ss Pharmaceut Co Ltd １，７−ナフチリジン誘導体及びこれを含有する薬剤
CA1265803A (fr) * 1985-07-11 1990-02-13 Claude Cotrel Amides substitues, leur preparation et les medicaments qui les contiennent

Also Published As

Publication number Publication date
JPH0432074B2 (Direct) 1992-05-28
EP0256556A1 (en) 1988-02-24
US4866176A (en) 1989-09-12
CA1300630C (en) 1992-05-12

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