JPS6330309B2 - - Google Patents

Info

Publication number
JPS6330309B2
JPS6330309B2 JP57003238A JP323882A JPS6330309B2 JP S6330309 B2 JPS6330309 B2 JP S6330309B2 JP 57003238 A JP57003238 A JP 57003238A JP 323882 A JP323882 A JP 323882A JP S6330309 B2 JPS6330309 B2 JP S6330309B2
Authority
JP
Japan
Prior art keywords
methyl
benzothiazine
pyridyl
dioxide
carboxamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP57003238A
Other languages
English (en)
Japanese (ja)
Other versions
JPS57139076A (en
Inventor
Jooji Ronbaadeino Josefu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PFIZER
Original Assignee
PFIZER
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PFIZER filed Critical PFIZER
Publication of JPS57139076A publication Critical patent/JPS57139076A/ja
Publication of JPS6330309B2 publication Critical patent/JPS6330309B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP57003238A 1981-01-15 1982-01-12 Benzothiazine dioxide derivative Granted JPS57139076A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/225,162 US4309427A (en) 1981-01-15 1981-01-15 Benzothiazine dioxide derivatives

Publications (2)

Publication Number Publication Date
JPS57139076A JPS57139076A (en) 1982-08-27
JPS6330309B2 true JPS6330309B2 (ref) 1988-06-17

Family

ID=22843790

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57003238A Granted JPS57139076A (en) 1981-01-15 1982-01-12 Benzothiazine dioxide derivative

Country Status (9)

Country Link
US (1) US4309427A (ref)
EP (1) EP0057059B1 (ref)
JP (1) JPS57139076A (ref)
DE (1) DE3260051D1 (ref)
DK (1) DK150069C (ref)
GR (1) GR75137B (ref)
HK (1) HK65286A (ref)
IE (1) IE51830B1 (ref)
MY (1) MY8600632A (ref)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4474955A (en) * 1981-06-17 1984-10-02 Vincenzo Iannella Process for preparing 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-[N-(2-pyridinyl)carboxamide]-1,1-dioxide, and its phosphoric ester
GT198276334A (es) * 1981-08-03 1984-01-10 Procedimiento e inter-medios para la produccion de carboxamidas de benzotiazina.
US4376204A (en) * 1981-10-05 1983-03-08 Pfizer Inc. 3-Hydroxy 2-methyl benzisothiazolines as intermediates in production of piroxicam
IT1168064B (it) * 1981-11-12 1987-05-20 Prodotti Antibiotici Spa Composto ad azione antinfiammatoria
IT8219486A0 (it) * 1982-02-05 1982-02-05 Chiesi Farma Spa Nuovi composti ad attivita'antiinfiammatoria, procedimento per la loro preparazione e relative composizioni farmaceutiche.
SU1306476A3 (ru) * 1982-06-17 1987-04-23 Пфайзер,Инк (Фирма) Способ получени 2-метил-3- @ -(2-пиридил)-карбамоил-3,4-дигидро-2 @ -1,2-бензтиазин-1,1-диоксида
EP0098422B1 (de) * 1982-07-07 1987-12-09 Siegfried Aktiengesellschaft Verfahren zur Herstellung von 4-Hydroxy-2-methyl-N-2-pyridyl-2H-1,2-benzothiazin-3-carboxamid 1,1-dioxid
IT1206525B (it) * 1982-12-10 1989-04-27 Zionale S R L A Roma Preparato anti-infiammatorio nonsteroideo, per il trattamento delle affezioni artroreumatiche e metodo per la sua preparazione
JPS608282A (ja) * 1983-06-27 1985-01-17 キエシ・フアルマチエウチチ・エツセ・ピ・ア ４―ピバロイルオキシ―２―メチル―２ｈ―１，２―ベンゾチアジン―３―〔ｎ―（２―ピリジル）―カルボキサミド〕―１，１―ジオキシドおよびそれを有効成分とする医薬
IT1194522B (it) * 1983-12-16 1988-09-22 Prodotti Antibiotici Spa Metodo di sintesi di derivanti benzotiazinici
US4551452A (en) * 1983-12-21 1985-11-05 Pfizer Inc. Anti-inflammatory 2-methyl-2H-1,2-benzo-(or -thieno-)thiazine-3-carboxamide 1,1-dioxide derivatives, compositions, and method of use therefor
JPS60184077A (ja) * 1984-02-23 1985-09-19 フアイザー・インコーポレーテツド 抗炎症性オキシム前駆薬
US4656265A (en) * 1984-06-21 1987-04-07 Pfizer Inc. Cyclic prodrugs of antiinflammatory oxicams
US4683306A (en) * 1984-07-13 1987-07-28 Yuhan Corporation Co., Ltd. Process for the preparation of 3,4-dihydro-2-substituted-2H-1,2-thiazine-carboxylic acid 1,1-dioxide derivatives
IT1196307B (it) * 1984-10-22 1988-11-16 Chiesi Farma Spa Formulazioni farmaceutiche acquose di piroxicam monoidrato
US4623486A (en) * 1985-05-29 1986-11-18 Pfizer Inc. [4-substituted benzoyloxy]-N-substituted-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxides having anti-arthritic activity
US4610982A (en) * 1985-06-03 1986-09-09 Pfizer Inc. Anti-inflammatory benzo- and thieno-1,2-thiazine-3-carboxamide 1,1-dioxide derivatives, compositions, and method of use therefor
WO1987006933A1 (en) * 1986-05-16 1987-11-19 Pfizer Inc. Benzothiazine dioxide derivatives
US5196410A (en) * 1986-10-31 1993-03-23 Pfizer Inc. Transdermal flux enhancing compositions
GB9824023D0 (en) * 1998-11-03 1998-12-30 Isis Innovation Surface functionalisation
EP2403825B1 (en) 2009-03-02 2019-09-11 Oxford Advanced Surfaces Ltd Chemical agents capable of forming covalent 3-d networks

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3591584A (en) * 1968-08-27 1971-07-06 Pfizer Benzothiazine dioxides
US3862319A (en) * 1971-02-09 1975-01-21 Pfizer Benzothiazine dioxides as anti-thromobotic agents
US3925371A (en) * 1974-09-23 1975-12-09 Mcneilab Inc Benzothiazine-1,1-dioxides
US4074048A (en) * 1976-05-10 1978-02-14 Warner-Lambert Company Process for the preparation of 4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxides

Also Published As

Publication number Publication date
IE820054L (en) 1982-07-15
HK65286A (en) 1986-09-12
MY8600632A (en) 1986-12-31
EP0057059B1 (en) 1984-03-07
DK150069B (da) 1986-12-01
JPS57139076A (en) 1982-08-27
DK13082A (da) 1982-07-16
DK150069C (da) 1987-10-19
IE51830B1 (en) 1987-04-01
US4309427A (en) 1982-01-05
EP0057059A1 (en) 1982-08-04
DE3260051D1 (en) 1984-04-12
GR75137B (ref) 1984-07-13

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