JPS6218523B2 - - Google Patents
Info
- Publication number
- JPS6218523B2 JPS6218523B2 JP5019877A JP5019877A JPS6218523B2 JP S6218523 B2 JPS6218523 B2 JP S6218523B2 JP 5019877 A JP5019877 A JP 5019877A JP 5019877 A JP5019877 A JP 5019877A JP S6218523 B2 JPS6218523 B2 JP S6218523B2
- Authority
- JP
- Japan
- Prior art keywords
- skin
- hair
- diisopropylamine dichloroacetate
- dichloroacetate
- people
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ILKBHIBYKSHTKQ-UHFFFAOYSA-N Diisopropylamine dichloroacetate Chemical compound OC(=O)C(Cl)Cl.CC(C)NC(C)C ILKBHIBYKSHTKQ-UHFFFAOYSA-N 0.000 claims description 30
- 229940084113 diisopropylamine dichloroacetate Drugs 0.000 claims description 30
- 239000006210 lotion Substances 0.000 claims description 24
- 239000002537 cosmetic Substances 0.000 claims description 23
- 239000006071 cream Substances 0.000 claims description 10
- -1 lipstick Substances 0.000 claims description 5
- 239000000843 powder Substances 0.000 claims description 4
- 239000002453 shampoo Substances 0.000 claims description 3
- 239000000839 emulsion Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 description 25
- 210000003491 skin Anatomy 0.000 description 24
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 15
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 9
- 239000000203 mixture Substances 0.000 description 8
- 235000019441 ethanol Nutrition 0.000 description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 7
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- 230000008859 change Effects 0.000 description 6
- 239000003205 fragrance Substances 0.000 description 6
- 238000002156 mixing Methods 0.000 description 6
- 239000002904 solvent Substances 0.000 description 6
- 238000003756 stirring Methods 0.000 description 6
- 201000004384 Alopecia Diseases 0.000 description 5
- 230000003676 hair loss Effects 0.000 description 5
- 208000024963 hair loss Diseases 0.000 description 5
- RVSTWRHIGKXTLG-UHFFFAOYSA-N Pangamic acid Natural products CC(C)N(C(C)C)C(N(C(C)C)C(C)C)C(=O)OCC(O)C(O)C(O)C(O)C(O)=O RVSTWRHIGKXTLG-UHFFFAOYSA-N 0.000 description 4
- 239000012153 distilled water Substances 0.000 description 4
- 230000003779 hair growth Effects 0.000 description 4
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 4
- 229940055705 pangamic acid Drugs 0.000 description 4
- ZQTHOIGMSJMBLM-BUJSFMDZSA-N pangamic acid Chemical compound CN(C)CC(=O)OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O ZQTHOIGMSJMBLM-BUJSFMDZSA-N 0.000 description 4
- 108700024047 pangamic acid Proteins 0.000 description 4
- 239000012071 phase Substances 0.000 description 4
- CUEHNLMLFJFMER-FOUMNBMASA-N (2r,3s,4r,5r)-6-[2-[di(propan-2-yl)amino]acetyl]oxy-2,3,4,5-tetrahydroxyhexanoic acid Chemical compound CC(C)N(C(C)C)CC(=O)OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O CUEHNLMLFJFMER-FOUMNBMASA-N 0.000 description 3
- PSFIFYQZCXJHJW-UHFFFAOYSA-N 2,2-dichloroacetate;diethylazanium Chemical compound CC[NH2+]CC.[O-]C(=O)C(Cl)Cl PSFIFYQZCXJHJW-UHFFFAOYSA-N 0.000 description 3
- 230000004913 activation Effects 0.000 description 3
- 235000011187 glycerol Nutrition 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 239000004166 Lanolin Substances 0.000 description 2
- 238000001467 acupuncture Methods 0.000 description 2
- 230000032683 aging Effects 0.000 description 2
- 230000003796 beauty Effects 0.000 description 2
- 235000013871 bee wax Nutrition 0.000 description 2
- 239000012166 beeswax Substances 0.000 description 2
- 229960000541 cetyl alcohol Drugs 0.000 description 2
- 210000003128 head Anatomy 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 235000019388 lanolin Nutrition 0.000 description 2
- 229940039717 lanolin Drugs 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 239000003921 oil Substances 0.000 description 2
- 230000003658 preventing hair loss Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 230000037303 wrinkles Effects 0.000 description 2
- PKDBCJSWQUOKDO-UHFFFAOYSA-M 2,3,5-triphenyltetrazolium chloride Chemical compound [Cl-].C1=CC=CC=C1C(N=[N+]1C=2C=CC=CC=2)=NN1C1=CC=CC=C1 PKDBCJSWQUOKDO-UHFFFAOYSA-M 0.000 description 1
- 239000005995 Aluminium silicate Substances 0.000 description 1
- 235000010919 Copernicia prunifera Nutrition 0.000 description 1
- 244000180278 Copernicia prunifera Species 0.000 description 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
- 208000001840 Dandruff Diseases 0.000 description 1
- 206010015150 Erythema Diseases 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 229930003270 Vitamin B Natural products 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 239000012190 activator Substances 0.000 description 1
- 230000007059 acute toxicity Effects 0.000 description 1
- 231100000403 acute toxicity Toxicity 0.000 description 1
- 235000012211 aluminium silicate Nutrition 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 239000008346 aqueous phase Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 229940092738 beeswax Drugs 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 235000013869 carnauba wax Nutrition 0.000 description 1
- 239000004203 carnauba wax Substances 0.000 description 1
- 239000004359 castor oil Substances 0.000 description 1
- 235000019438 castor oil Nutrition 0.000 description 1
- 230000003749 cleanliness Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 229940120124 dichloroacetate Drugs 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 230000037336 dry skin Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000004945 emulsification Methods 0.000 description 1
- 231100000321 erythema Toxicity 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000010253 intravenous injection Methods 0.000 description 1
- 230000005722 itchiness Effects 0.000 description 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- 239000002932 luster Substances 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000011259 mixed solution Substances 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 229940100486 rice starch Drugs 0.000 description 1
- 238000007665 sagging Methods 0.000 description 1
- 210000004761 scalp Anatomy 0.000 description 1
- 210000004927 skin cell Anatomy 0.000 description 1
- 230000004215 skin function Effects 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
- 235000019156 vitamin B Nutrition 0.000 description 1
- 239000011720 vitamin B Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- XOOUIPVCVHRTMJ-UHFFFAOYSA-L zinc stearate Chemical compound [Zn+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O XOOUIPVCVHRTMJ-UHFFFAOYSA-L 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5019877A JPS53136528A (en) | 1977-04-30 | 1977-04-30 | Cosmetics |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5019877A JPS53136528A (en) | 1977-04-30 | 1977-04-30 | Cosmetics |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS53136528A JPS53136528A (en) | 1978-11-29 |
| JPS6218523B2 true JPS6218523B2 (enExample) | 1987-04-23 |
Family
ID=12852430
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP5019877A Granted JPS53136528A (en) | 1977-04-30 | 1977-04-30 | Cosmetics |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS53136528A (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2501043A1 (fr) * | 1981-03-05 | 1982-09-10 | Lefoll Jean | Application des acides halogenoacetiques a dose homeopathique, en medecine humaine et veterinaire, dans les produits d'hygiene corporelle et dans les produits phytopharmaceutiques |
| JPH0657652B2 (ja) * | 1985-07-19 | 1994-08-03 | 鐘紡株式会社 | 皮膚老化防止化粧料 |
| JPS6287506A (ja) * | 1985-10-15 | 1987-04-22 | Kanebo Ltd | 皮膚老化防止化粧料 |
| JPS62145009A (ja) * | 1985-12-17 | 1987-06-29 | Kanebo Ltd | 養毛化粧料 |
| JPS62148414A (ja) * | 1985-12-23 | 1987-07-02 | Kanebo Ltd | 皮膚化粧料 |
| JP2793646B2 (ja) * | 1989-08-18 | 1998-09-03 | 鐘紡株式会社 | 養毛化粧料 |
| JPH06100430A (ja) * | 1992-09-22 | 1994-04-12 | Kanebo Ltd | 表皮角質化促進剤 |
| JP3256369B2 (ja) * | 1994-03-03 | 2002-02-12 | カネボウ株式会社 | 皮膚化粧料 |
| JP6027752B2 (ja) * | 2011-02-21 | 2016-11-16 | 第一三共ヘルスケア株式会社 | ＡＧＥｓ生成抑制剤 |
| JP5969787B2 (ja) * | 2011-03-23 | 2016-08-17 | 第一三共ヘルスケア株式会社 | 生体内のメイラード反応抑制剤またはＡＧＥｓ生成抑制剤 |
-
1977
- 1977-04-30 JP JP5019877A patent/JPS53136528A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS53136528A (en) | 1978-11-29 |
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