JPS62108897A - アスカマイシン誘導体及びその合成法並びに制癌剤 - Google Patents

アスカマイシン誘導体及びその合成法並びに制癌剤

Info

Publication number
JPS62108897A
JPS62108897A JP24739285A JP24739285A JPS62108897A JP S62108897 A JPS62108897 A JP S62108897A JP 24739285 A JP24739285 A JP 24739285A JP 24739285 A JP24739285 A JP 24739285A JP S62108897 A JPS62108897 A JP S62108897A
Authority
JP
Japan
Prior art keywords
ascamycin
compound
group
formula
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP24739285A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0560479B2 (enExample
Inventor
Kiyoshi Isono
磯野　清
Makoto Ubukata
信 生方
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RIKEN
Original Assignee
RIKEN
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RIKEN filed Critical RIKEN
Priority to JP24739285A priority Critical patent/JPS62108897A/ja
Publication of JPS62108897A publication Critical patent/JPS62108897A/ja
Publication of JPH0560479B2 publication Critical patent/JPH0560479B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
JP24739285A 1985-11-05 1985-11-05 アスカマイシン誘導体及びその合成法並びに制癌剤 Granted JPS62108897A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP24739285A JPS62108897A (ja) 1985-11-05 1985-11-05 アスカマイシン誘導体及びその合成法並びに制癌剤

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP24739285A JPS62108897A (ja) 1985-11-05 1985-11-05 アスカマイシン誘導体及びその合成法並びに制癌剤

Publications (2)

Publication Number Publication Date
JPS62108897A true JPS62108897A (ja) 1987-05-20
JPH0560479B2 JPH0560479B2 (enExample) 1993-09-02

Family

ID=17162742

Family Applications (1)

Application Number Title Priority Date Filing Date
JP24739285A Granted JPS62108897A (ja) 1985-11-05 1985-11-05 アスカマイシン誘導体及びその合成法並びに制癌剤

Country Status (1)

Country Link
JP (1) JPS62108897A (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824657A (en) * 1997-03-18 1998-10-20 Cubist Pharmaceuticals, Inc. Aminoacyl sulfamides for the treatment of hyperproliferative disorders
DE10340068A1 (de) * 2003-08-28 2005-03-24 TransMIT Gesellschaft für Technologietransfer mbH Substrate für die Inhibierung der Adenylierungsdomänen nicht-ribosomaler Peptidsynthetasen
US7951810B2 (en) 2005-02-04 2011-05-31 Millennium Pharmaceuticals, Inc. Substituted pyrrolo[2,3-d]pyrimidines as inhibitors of E1 activating enzymes
US8207177B2 (en) 2006-02-02 2012-06-26 Millennium Pharmaceuticals, Inc. Inhibitors of E1 activating enzymes
US9187482B2 (en) 2009-05-14 2015-11-17 Millennium Pharmaceuticals, Inc. Hydrochloride salt of((1S,2S,4R)-4-{4-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-2-hydroxycyclopentyl)methyl sulfamate

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824657A (en) * 1997-03-18 1998-10-20 Cubist Pharmaceuticals, Inc. Aminoacyl sulfamides for the treatment of hyperproliferative disorders
DE10340068A1 (de) * 2003-08-28 2005-03-24 TransMIT Gesellschaft für Technologietransfer mbH Substrate für die Inhibierung der Adenylierungsdomänen nicht-ribosomaler Peptidsynthetasen
US7951810B2 (en) 2005-02-04 2011-05-31 Millennium Pharmaceuticals, Inc. Substituted pyrrolo[2,3-d]pyrimidines as inhibitors of E1 activating enzymes
US8207177B2 (en) 2006-02-02 2012-06-26 Millennium Pharmaceuticals, Inc. Inhibitors of E1 activating enzymes
US9187482B2 (en) 2009-05-14 2015-11-17 Millennium Pharmaceuticals, Inc. Hydrochloride salt of((1S,2S,4R)-4-{4-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-2-hydroxycyclopentyl)methyl sulfamate
US10016427B2 (en) 2009-05-14 2018-07-10 Millennium Pharmacetuicals, Inc. Hydrochloride salt of((1S,2S,4R)-4-{4-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-7H-pyrrolo[2,3-D]pyrimidin-7-YL}-2-hydroxycyclopentyl) methyl sulfamate

Also Published As

Publication number Publication date
JPH0560479B2 (enExample) 1993-09-02

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