JPS61247460A - 注射剤用止栓 - Google Patents
注射剤用止栓Info
- Publication number
- JPS61247460A JPS61247460A JP60089981A JP8998185A JPS61247460A JP S61247460 A JPS61247460 A JP S61247460A JP 60089981 A JP60089981 A JP 60089981A JP 8998185 A JP8998185 A JP 8998185A JP S61247460 A JPS61247460 A JP S61247460A
- Authority
- JP
- Japan
- Prior art keywords
- stopper
- weight
- injection
- rubber
- softener
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000002347 injection Methods 0.000 title claims description 48
- 239000007924 injection Substances 0.000 title claims description 48
- 239000003814 drug Substances 0.000 title description 2
- 229940079593 drug Drugs 0.000 title description 2
- 229920000642 polymer Polymers 0.000 claims description 25
- 229920001971 elastomer Polymers 0.000 claims description 21
- 239000005060 rubber Substances 0.000 claims description 20
- 239000000203 mixture Substances 0.000 claims description 15
- 239000012188 paraffin wax Substances 0.000 claims description 11
- 229920002725 thermoplastic elastomer Polymers 0.000 claims description 8
- 229920001083 polybutene Polymers 0.000 claims description 7
- 229920002367 Polyisobutene Polymers 0.000 claims description 6
- 238000002156 mixing Methods 0.000 claims description 5
- 229920005672 polyolefin resin Polymers 0.000 claims description 5
- 229920001577 copolymer Polymers 0.000 claims description 4
- 150000004945 aromatic hydrocarbons Chemical class 0.000 claims description 3
- 229920003244 diene elastomer Polymers 0.000 claims description 2
- 239000004902 Softening Agent Substances 0.000 claims 1
- 238000000034 method Methods 0.000 description 15
- 239000000243 solution Substances 0.000 description 13
- 239000000463 material Substances 0.000 description 10
- 238000004519 manufacturing process Methods 0.000 description 9
- 238000000465 moulding Methods 0.000 description 8
- RRHGJUQNOFWUDK-UHFFFAOYSA-N Isoprene Chemical compound CC(=C)C=C RRHGJUQNOFWUDK-UHFFFAOYSA-N 0.000 description 6
- 239000000047 product Substances 0.000 description 6
- 239000000654 additive Substances 0.000 description 5
- 238000007906 compression Methods 0.000 description 5
- 230000006835 compression Effects 0.000 description 5
- -1 proprene Chemical compound 0.000 description 5
- 239000004636 vulcanized rubber Substances 0.000 description 5
- KAKZBPTYRLMSJV-UHFFFAOYSA-N Butadiene Chemical compound C=CC=C KAKZBPTYRLMSJV-UHFFFAOYSA-N 0.000 description 4
- 125000003118 aryl group Chemical group 0.000 description 4
- 229920001400 block copolymer Polymers 0.000 description 4
- 238000004140 cleaning Methods 0.000 description 4
- 239000010419 fine particle Substances 0.000 description 4
- 239000000178 monomer Substances 0.000 description 4
- 239000003208 petroleum Substances 0.000 description 4
- 125000004432 carbon atom Chemical group C* 0.000 description 3
- 230000032798 delamination Effects 0.000 description 3
- 238000010828 elution Methods 0.000 description 3
- 238000003780 insertion Methods 0.000 description 3
- 230000037431 insertion Effects 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 239000013557 residual solvent Substances 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- 238000004659 sterilization and disinfection Methods 0.000 description 3
- 229920003002 synthetic resin Polymers 0.000 description 3
- 238000010998 test method Methods 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 238000004073 vulcanization Methods 0.000 description 3
- VXNZUUAINFGPBY-UHFFFAOYSA-N 1-Butene Chemical compound CCC=C VXNZUUAINFGPBY-UHFFFAOYSA-N 0.000 description 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- VQTUBCCKSQIDNK-UHFFFAOYSA-N Isobutene Chemical group CC(C)=C VQTUBCCKSQIDNK-UHFFFAOYSA-N 0.000 description 2
- UFWIBTONFRDIAS-UHFFFAOYSA-N Naphthalene Chemical group C1=CC=CC2=CC=CC=C21 UFWIBTONFRDIAS-UHFFFAOYSA-N 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 238000007796 conventional method Methods 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 150000001993 dienes Chemical class 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000000945 filler Substances 0.000 description 2
- 239000011256 inorganic filler Substances 0.000 description 2
- 229910003475 inorganic filler Inorganic materials 0.000 description 2
- 239000010445 mica Substances 0.000 description 2
- 229910052618 mica group Inorganic materials 0.000 description 2
- 230000000704 physical effect Effects 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 229920002857 polybutadiene Polymers 0.000 description 2
- 239000002952 polymeric resin Substances 0.000 description 2
- 238000006116 polymerization reaction Methods 0.000 description 2
- 230000000379 polymerizing effect Effects 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 239000003381 stabilizer Substances 0.000 description 2
- 229920000468 styrene butadiene styrene block copolymer Polymers 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000000454 talc Substances 0.000 description 2
- 229910052623 talc Inorganic materials 0.000 description 2
- LIKMAJRDDDTEIG-UHFFFAOYSA-N 1-hexene Chemical compound CCCCC=C LIKMAJRDDDTEIG-UHFFFAOYSA-N 0.000 description 1
- WSSSPWUEQFSQQG-UHFFFAOYSA-N 4-methyl-1-pentene Chemical compound CC(C)CC=C WSSSPWUEQFSQQG-UHFFFAOYSA-N 0.000 description 1
- 101100538447 Aspergillus terreus (strain NIH 2624 / FGSC A1156) trt3 gene Proteins 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 1
- 239000005977 Ethylene Substances 0.000 description 1
- 239000004606 Fillers/Extenders Substances 0.000 description 1
- 244000043261 Hevea brasiliensis Species 0.000 description 1
- 239000005062 Polybutadiene Substances 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000006096 absorbing agent Substances 0.000 description 1
- 150000001336 alkenes Chemical class 0.000 description 1
- XYLMUPLGERFSHI-UHFFFAOYSA-N alpha-Methylstyrene Chemical compound CC(=C)C1=CC=CC=C1 XYLMUPLGERFSHI-UHFFFAOYSA-N 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- FACXGONDLDSNOE-UHFFFAOYSA-N buta-1,3-diene;styrene Chemical compound C=CC=C.C=CC1=CC=CC=C1.C=CC1=CC=CC=C1 FACXGONDLDSNOE-UHFFFAOYSA-N 0.000 description 1
- 229920005549 butyl rubber Polymers 0.000 description 1
- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 239000006229 carbon black Substances 0.000 description 1
- 229920005556 chlorobutyl Polymers 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 238000007334 copolymerization reaction Methods 0.000 description 1
- 229920006038 crystalline resin Polymers 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000000806 elastomer Substances 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 230000001747 exhibiting effect Effects 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 238000001879 gelation Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000012760 heat stabilizer Substances 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 238000010030 laminating Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 239000002480 mineral oil Substances 0.000 description 1
- 235000010446 mineral oil Nutrition 0.000 description 1
- 229920003052 natural elastomer Polymers 0.000 description 1
- 229920001194 natural rubber Polymers 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 description 1
- YWAKXRMUMFPDSH-UHFFFAOYSA-N pentene Chemical compound CCCC=C YWAKXRMUMFPDSH-UHFFFAOYSA-N 0.000 description 1
- 239000004014 plasticizer Substances 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001195 polyisoprene Polymers 0.000 description 1
- 239000010734 process oil Substances 0.000 description 1
- 229920001384 propylene homopolymer Polymers 0.000 description 1
- 229920005604 random copolymer Polymers 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 229920006132 styrene block copolymer Polymers 0.000 description 1
- 150000003440 styrenes Chemical class 0.000 description 1
- 239000000057 synthetic resin Substances 0.000 description 1
- 238000002834 transmittance Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 239000004711 α-olefin Substances 0.000 description 1
Landscapes
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP60089981A JPS61247460A (ja) | 1985-04-26 | 1985-04-26 | 注射剤用止栓 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP60089981A JPS61247460A (ja) | 1985-04-26 | 1985-04-26 | 注射剤用止栓 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS61247460A true JPS61247460A (ja) | 1986-11-04 |
JPH024296B2 JPH024296B2 (enrdf_load_stackoverflow) | 1990-01-26 |
Family
ID=13985839
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP60089981A Granted JPS61247460A (ja) | 1985-04-26 | 1985-04-26 | 注射剤用止栓 |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS61247460A (enrdf_load_stackoverflow) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0999146A2 (en) | 1998-11-04 | 2000-05-10 | Taisei Plas Co., Ltd. | Pierceable stopper and method of producing the same |
WO2010103988A1 (ja) * | 2009-03-13 | 2010-09-16 | アロン化成株式会社 | 医療容器栓体用エラストマー組成物 |
JP2010227285A (ja) * | 2009-03-27 | 2010-10-14 | Aron Kasei Co Ltd | 医療容器栓体用複合エラストマー組成物 |
CN102844373A (zh) * | 2010-04-28 | 2012-12-26 | 安隆化成株式会社 | 弹性体组成物以及医疗容器用塞子 |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2006328A4 (en) | 2006-04-13 | 2011-03-02 | Kaneka Corp | COMPOSITION FOR RUBBER STOP AND RADIATION STOPPER FOR MEDICAL APPLICATION |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5138729A (en) * | 1974-09-27 | 1976-03-31 | Taro Hayashi | Mokuzokaoku no gaihekikochikuhoho |
JPS5653173A (en) * | 1979-10-09 | 1981-05-12 | Terumo Corp | Gasket for syringe |
JPS5928965A (ja) * | 1982-08-11 | 1984-02-15 | テルモ株式会社 | 医療容器用栓体 |
JPS59131613A (ja) * | 1983-01-18 | 1984-07-28 | Mitsubishi Petrochem Co Ltd | エラストマー状成形体の製造方法 |
JPS61218650A (ja) * | 1985-03-25 | 1986-09-29 | Mitsubishi Petrochem Co Ltd | 熱可塑性エラストマー組成物 |
-
1985
- 1985-04-26 JP JP60089981A patent/JPS61247460A/ja active Granted
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5138729A (en) * | 1974-09-27 | 1976-03-31 | Taro Hayashi | Mokuzokaoku no gaihekikochikuhoho |
JPS5653173A (en) * | 1979-10-09 | 1981-05-12 | Terumo Corp | Gasket for syringe |
JPS5928965A (ja) * | 1982-08-11 | 1984-02-15 | テルモ株式会社 | 医療容器用栓体 |
JPS59131613A (ja) * | 1983-01-18 | 1984-07-28 | Mitsubishi Petrochem Co Ltd | エラストマー状成形体の製造方法 |
JPS61218650A (ja) * | 1985-03-25 | 1986-09-29 | Mitsubishi Petrochem Co Ltd | 熱可塑性エラストマー組成物 |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0999146A2 (en) | 1998-11-04 | 2000-05-10 | Taisei Plas Co., Ltd. | Pierceable stopper and method of producing the same |
US6607685B2 (en) | 1998-11-04 | 2003-08-19 | Taisei Plas Co., Ltd. | Method of producing pierceable stopper |
WO2010103988A1 (ja) * | 2009-03-13 | 2010-09-16 | アロン化成株式会社 | 医療容器栓体用エラストマー組成物 |
CN102256584A (zh) * | 2009-03-13 | 2011-11-23 | 安隆化成株式会社 | 医疗容器塞子用弹性体组成物 |
JP5199456B2 (ja) * | 2009-03-13 | 2013-05-15 | アロン化成株式会社 | 医療容器栓体用エラストマー組成物 |
JP2010227285A (ja) * | 2009-03-27 | 2010-10-14 | Aron Kasei Co Ltd | 医療容器栓体用複合エラストマー組成物 |
CN102844373A (zh) * | 2010-04-28 | 2012-12-26 | 安隆化成株式会社 | 弹性体组成物以及医疗容器用塞子 |
Also Published As
Publication number | Publication date |
---|---|
JPH024296B2 (enrdf_load_stackoverflow) | 1990-01-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
LAPS | Cancellation because of no payment of annual fees |