JPS61165311A - Hair tonic cosmetic - Google Patents

Abstract

PURPOSE:A hair tonic cosmetic that contains minoxidil and thyroid hormone as active ingredients, thus showing excellent hair tonic effect better than when it is used separately to hair roots, and being most suitable as a hair lotion for developing its action without side-effects such as skin eruption and rubefaction. CONSTITUTION:Minoxidil (2,4-diamino-6-piperidinopyridine-3-oxide), which has been used as a hypotensor and thyroid hormone are added to cosmetic bases as hair tonic components. Both active ingredients are soluble in alcohol and water and allowed to dissolve in these solvents, combined with perfumes, humectants, freshing agent and scalp stimulant by 1-10mg minoxidil, 0.025-10g thyroid hormone in 1l of the solution. Then, the resultant hair tonic is applied to hair roots. It can be used as a hair-dressing agent such as hair cream or pomade.

Description

DETAILED DESCRIPTION OF THE INVENTION Field of Industrial Application The present invention relates to a hair nourishing cosmetic that exerts a remarkable hair nourishing effect when applied to the hair roots.

Prior Art The present inventor has previously developed a hair-growth cosmetic containing minoxidil (2,4-diami/-6-biperidi/viriminone-3-oxide), which is currently used as an antihypertensive agent, as an active ingredient. It was disclosed as Special No. 11I56-185934. When the present inventor was developing a hair-growth cosmetic that more effectively exerts the hair growth-promoting effect of minoxidil, he focused on the effect of reducing the metabolism of the thyroid gland #a. When the hormone was blended into a minoxidil-containing cosmetic and applied to the hair roots, it was discovered that the hair-nourishing effect was even better than when both ingredients were applied alone, and the present invention was completed. .

DISCLOSURE OF THE INVENTION The gist of the present invention is that a hair nourishing cosmetic is characterized in that minoxidil and thyroid hormone are contained in a cosmetic base as hair nourishing ingredients. , is soluble in water, etc., and is obtained by dissolving both in these solvents and adding fragrances, humectants, refreshing agents, 9 scalp stimulants, etc. commonly used in the production of hair lotions, hair tonics, etc. 1 liter of component solution It usually contains 1 to 110 liters of minoxidil. Thyroid hormone 0.0
By dissolving in the range of 25 to io, 1, the purpose can be fully achieved. The hair nourishing cosmetics of this application are:
Due to its properties, it is most effective in hair lotion type, but it can also be used as hair styling products such as hair cream and pomade. Below are test examples and manufacturing examples in which the hair growth effect of the cosmetics of the present application was investigated. Incidentally, no skin rash, redness or other side effects due to the application of the cosmetic of the present invention were observed.

[Test Example 11 Effect of the cosmetic of the present application on mice] 20 mice (average body weight: 31 g) were depilated by applying 10% sodium sulfide to their heads, and thoroughly washed with water to form a depilated area of approximately 1cII+2. Divide into 4 groups of 5 mice each, apply the following mixed solution to each group twice a day in the morning and evening from the day after hair removal, and periodically remove 5 hairs from each mouse.
Its length was measured.

Group 1: ethanol 5ml + glycerin 0.5a + l +
Distilled water 4.5 ml No. 29: Minoxynol 50 mg 10 ethyl 5 ml + glycerin 0.51 + distilled water 4.5 ml Group 3: L-thyroxine sodium pentahydrate 10 mg + ethanol 5 ml 1
+ Glycerin 0.5 ml + Distilled water 4.51 Group 4: Minoxidil 50 g + Monothyroxine sodium pentahydrate 10-g + Ethanol 51 + Glycerin 0
．． 51 + distilled water 4.5 duck 1 14 days after hair removal 14 days after hair removal, the hair growth situation and the average value of 15 pulled hairs are shown below.

Group Macroscopic observation Average hair length (mm) Group 1
Insufficient hair growth 1.8 Group 2 Hair growth promoted but patchy 3.1 Group 3 〃2.7 Group 4 All over hair growth 4.2 [Example 1 Production of hair 0-silon 95% eta/- 50 (wt%) Glycerin 5 Minoxidil 0.5 thyroxine sodium pentahydrate 0.1 menthol
0.4 tofu Lashi tincture
1.0 resorcinol
0.5 fragrance 1.5 coloring agent
Appropriate amount of purified water (100%)
Mix and dissolve more than the appropriate amount to make a product.

Claims (1)

[Claims] A hair nourishing cosmetic containing minoxidil and thyroid hormone as hair nourishing ingredients.