JPS61165310A - Gray hair-preventing cosmetic - Google Patents

Gray hair-preventing cosmetic

Info

Publication number
JPS61165310A
JPS61165310A JP426385A JP426385A JPS61165310A JP S61165310 A JPS61165310 A JP S61165310A JP 426385 A JP426385 A JP 426385A JP 426385 A JP426385 A JP 426385A JP S61165310 A JPS61165310 A JP S61165310A
Authority
JP
Japan
Prior art keywords
hair
minoxidil
gray
lotion
gray hair
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP426385A
Other languages
Japanese (ja)
Inventor
Takeo Kinji
金児　猛夫
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to JP426385A priority Critical patent/JPS61165310A/en
Publication of JPS61165310A publication Critical patent/JPS61165310A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)

Abstract

PURPOSE:A gray hair-preventing cosmetic that contains, as an active ingredient, minoxidil, thus showing action to prevent gray hair from growing, causing no side-effects such a eruption or rubefaction, when it is applied to hair roots and being suitable for use in the form of a hair lotion. CONSTITUTION:The objective cosmetic contains, as an active ingredient, minoxidil (=2,4-diamino-6-pipridinopyrimidine-3-oxide), which is used as a hypotensor and allow hairs to grow specifically, when it is applied to skins. Minoxidil is soluble in an organic solvent such as ethanol or acetone and also dissolves in water by 2mg/ml. Therefore, it is dissolved in a solvent such as alcohol or water by 1-10g and used as a hair lotion or hair tonic together with perfumes, humectants, refreshing agents and skin stimulant. The lotion or tonic is applied to hair roots regularly. It is also used as a hair-dressing agent such as hair cream.

Description

【発明の詳細な説明】 産業上の利用分野 本発明は、著しい白髪防止作用を示す毛髪化粧料に関す
るものである。DETAILED DESCRIPTION OF THE INVENTION Field of Industrial Application The present invention relates to a hair cosmetic that exhibits a remarkable effect on preventing gray hair.

従来技術及び問題点 一般に、白髪は、加齢と共に増加するため、老化のイメ
ージと結び付きやす（、白髪を気にする者は、白髪染め
等に頼ることが多いが、毛髪の色がまだらになったり、
皮膚に発疹を生ずるなどの不満足な面がみられた６本発
明者は、先に、降圧剤として現在使用されているミノキ
シジルについて、これの溶液を皮膚に塗布することによ
り、毛髪を特異的に成長促進せしめる作用を有すること
を見出だし、特開昭５８−８８３０７号としてこれを開
示したが、本発明者は、ミノキシジルについて、更に研
究をかさねた結果、この物質に白髪の発生を抑える作用
を見出だし、本発明を完成したものである。Prior Art and Problems In general, gray hair increases with age, so it is easily associated with the image of aging (Those who are concerned about gray hair often resort to gray hair dyeing, etc. ,
6 The present inventors have previously discovered that minoxidil, which is currently used as an antihypertensive agent, has been found to have unsatisfactory aspects such as rashes on the skin. The inventor of the present invention discovered that minoxidil has the effect of promoting hair growth, and disclosed this in Japanese Patent Application Laid-Open No. 88307/1983. After further research on minoxidil, the present inventor discovered that this substance has the effect of suppressing the occurrence of gray hair. The heading completes the invention.

解決手段 本発明の要旨は、ミノキシジル（２，４−ノアミノ−６
−ビベリノノピリミシンー３−オキサイド）を有効成分
として化粧料基剤中に含有せしめたことを特徴とする白
髪防止化粧料にある。以下詳細に説明する。ミノキシジ
ルは、プロピレングリコール、エタノール、アセトン等
の有機溶媒に可溶であり又水にも、２論ｇ／−１程度ま
で溶解する。従って、ミノキシジルを、アルコール類、
水などの溶媒に溶かし、これにヘアローション、ヘアト
ニックなどの製造上通常に用いられている香料、湿潤削
、清涼剤、皮膚刺激剤等を加えて成る溶液１リツトル中
に、通常１−１０ｇの範囲で溶存せしめたものを、定期
的に毛根部に塗布することにより、白髪の発生を十分に
防止することができる。本願白髪防止化粧料は、その性
質上、ヘアミージョンタイプが最も効果的であるが、へ
７クリーム、ポマード等の′！ＩＩｊｉ料として用いる
ことも可能である。Solution The gist of the present invention is that minoxidil (2,4-noamino-6
-Bivelinonopyrimicin-3-oxide) as an active ingredient in a cosmetic base. This will be explained in detail below. Minoxidil is soluble in organic solvents such as propylene glycol, ethanol, acetone, etc., and is also soluble in water to a level of about 2 theoretical g/-1. Therefore, minoxidil, alcohol,
Usually 1 to 10 g per liter of solution is prepared by dissolving in a solvent such as water and adding fragrances, moisturizers, cooling agents, skin irritants, etc. commonly used in the production of hair lotions, hair tonics, etc. By regularly applying a dissolved product to the hair roots, the occurrence of gray hair can be sufficiently prevented. Due to its nature, hair melon type cosmetics are the most effective for preventing gray hair, but products such as He7 cream and pomade are the most effective. It is also possible to use it as a material.

以下に、ミノキシノルの白髪防止効果を検討した試験例
及びミノキシノル配合の毛髪化粧料の製造実施例を掲げ
る。尚、本願実験において、本願化粧料の塗布にもとず
く皮膚の発疹、発赤その他の副作用は一切認められなか
った。以下における単位は、すべて重量％である。Listed below are test examples in which the effect of minoxynol on preventing gray hair and production examples of hair cosmetics containing minoxynol are listed. In the present experiment, no skin rash, redness, or other side effects were observed due to the application of the present cosmetic. All units below are weight %.

［試験例１ 本発明にかかる化粧料の有効性を検定するため以下の供
試液１．２を調製した。[Test Example 1 In order to test the effectiveness of the cosmetic composition according to the present invention, the following sample solution 1.2 was prepared.

供試液１： ９５％エタ／−ル　　　　　　５０（％）グリセリン　
　　　　　　　　５ イオン交換水　　　　　　　　４５ 供試液２： ９５％エタノール　　　　　　５０（％）ミノキシノル
　　　　　　　　　０．５グリセリン　　　　　　　　
　５ イオン交換水　　　　　　　　４４．５次に、４０歳か
ら、６０歳までの白髪のみえはじめた２０人をアトラン
ダムに２群に分け、第１群１０名は供試液１を、第２群
には供試液２を、週２回頭髪に塗布し、塗布開始前及び
塗布開始後６Ｗｉ月における頭頂部毛髪１０００本あた
りの白髪の本数をかぞえた結果を次表に示す。Test solution 1: 95% ethanol/50(%) glycerin
5 Ion exchange water 45 Test solution 2: 95% ethanol 50(%) minoxynol 0.5 glycerin
5 Ion exchange water 44.5Next, 20 people between the ages of 40 and 60 who started to see gray hair were randomly divided into two groups.The 10 people in the first group received test solution 1, and the second group received test solution 1. Test solution 2 was applied to the hair twice a week, and the number of gray hairs per 1000 hairs on the top of the head was counted before and 6 months after the start of application, and the results are shown in the following table.

第１群： パネルＮｏ、　　塗布開始　塗布６箇月前白髪数　後の
白髪数 ４　　　　　　　　　　　５６　　　　　　　Ｊ　　３
９第２群： パネルＮｏ、　　塗布開始　　塗布６箇月前白髪数　　
後の白髪数 結果から明らかなように、ミノキシノル添加の供試液２
の使用群では着しく白髪本数の減少ないし増加の抑制が
みられた。Group 1: Panel No. Start of application Number of gray hairs 6 months before application Number of gray hairs after application 4 56 J 3
9 Group 2: Panel No. Start of application Number of gray hairs 6 months before application
As is clear from the gray hair count results, test solution 2 containing minoxynol
In the group using the drug, there was a significant decrease in the number of gray hairs or a suppression of the increase in the number of gray hairs.

［実ｍ例１　　ヘア０−シジンの製造 ９５％エタノール　　　　　５０（吻）ミノキシノル　
　　　　　　　０．５ １−メントール　　　　　　　０．４ トウ〃ラシチンキ　　　　　　１．０ レゾルシン　　　　　　　　　０．５ グリセリン　　　　　　　　５ 香料　　　　　　　　　　　　１・５ 着色料　　　　　　　　　　適量 以上を混合溶解して、全量を１００とし製品とする。[Example 1 Production of hair 0-cysine 95% ethanol 50 (proboscis) minoxynol
0.5 1-Menthol 0.4 Pepper tincture 1.0 Resorcinol 0.5 Glycerin 5 Flavor 1.5 Coloring agent Mix and dissolve an appropriate amount or more to make a total amount of 100 to form a product.

Claims (1)

【特許請求の範囲】[Claims] ミノキシジル（２，４−ジアミノ−６−ピペリジノピリ
ミジン−３−オキサイド）を、有効成分として含有する
ことを特徴とする白髪防止化粧料。A cosmetic for preventing gray hair, comprising minoxidil (2,4-diamino-6-piperidinopyrimidine-3-oxide) as an active ingredient.
JP426385A 1985-01-14 1985-01-14 Gray hair-preventing cosmetic Pending JPS61165310A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP426385A JPS61165310A (en) 1985-01-14 1985-01-14 Gray hair-preventing cosmetic

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP426385A JPS61165310A (en) 1985-01-14 1985-01-14 Gray hair-preventing cosmetic

Publications (1)

Publication Number Publication Date
JPS61165310A true JPS61165310A (en) 1986-07-26

Family

ID=11579652

Family Applications (1)

Application Number Title Priority Date Filing Date
JP426385A Pending JPS61165310A (en) 1985-01-14 1985-01-14 Gray hair-preventing cosmetic

Country Status (1)

Country Link
JP (1) JPS61165310A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0260697A2 (en) 1986-09-18 1988-03-23 Lion Corporation Composition for application to hair
US5378453A (en) * 1988-03-16 1995-01-03 Lion Corporation Composition for preventing graying of the hair and restoring grayed hair to its natural color
WO2003022207A3 (en) * 2001-09-07 2003-12-24 Sarfaraz K Niazi Method and composition for reducing sebum secretion in mammals
JP2010517938A (en) * 2006-10-27 2010-05-27 ジュセッペ・トリジャンテ Compounds and methods for preventing hair loss

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0260697A2 (en) 1986-09-18 1988-03-23 Lion Corporation Composition for application to hair
US5378453A (en) * 1988-03-16 1995-01-03 Lion Corporation Composition for preventing graying of the hair and restoring grayed hair to its natural color
WO2003022207A3 (en) * 2001-09-07 2003-12-24 Sarfaraz K Niazi Method and composition for reducing sebum secretion in mammals
JP2010517938A (en) * 2006-10-27 2010-05-27 ジュセッペ・トリジャンテ Compounds and methods for preventing hair loss

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