JPS60116616A - Cosmetic - Google Patents

Abstract

PURPOSE:A cosmetic obtained by incorporating an allantoin and an L-ascorbic acid together therein, and capable of enhancing synergistically the effect on improvement in skin roughening. CONSTITUTION:A cosmetic containing at least one or more selected from the group consisting of allantoin expressed by the formula and derivatives thereof, e.g. dihydroxyaluminum allantoate, and at least one or more selected from the group consisting of L-ascorbic acid and esters thereof, e.g. L-ascorbic acid monostearate. The cosmetic containing the allantoin and L-ascorbic acid, etc. has effect on prevention of skin roughening, curing wounds and beautification and whitening, etc. The use of both together increases synergistically the effect on improvement in the skin roughening. The amounts of the components to be incorporated are as follows: 0.001-5.0wt%, preferably 0.05-3.0wt% allantoin and >=0.001wt%, preferably about 10.0wt% L-ascorbic acid.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a novel cosmetic that has significantly improved effects on improving rough skin.

The stratum corneum of the skin maintains an appropriate amount of water through water supply from the body and water absorption from the outside, and generally has a water content of 10
~20% amount is said to be optimal. When this amount is less than 10%, the skin becomes dry and rough, and in extreme cases, cracks may appear. To solve this problem, conventional cosmetics containing moisturizing agents such as sodium lactate, glycerin, sodium pyrrolidone carboxylate, and propylene glycol have been used.

However, these moisturizers have a physicochemical effect on the skin surface and function to supply moisture to the stratum corneum, and their effect is temporary and greatly influenced by environmental conditions. It had the following drawback.

On the other hand, in addition to the above-mentioned moisturizers, cosmetics containing allantoin, L-ascorbic acid, etc. have been proposed as having effects such as preventing rough skin, healing wounds, and whitening skin. However, when each of these is blended individually, the effect cannot be confirmed in actual usage conditions ω. In view of these circumstances, the inventors conducted intensive research to obtain cosmetics with excellent effects on improving rough skin.
The above object can be achieved by combining the selected one or more with one or two or more selected from the group consisting of L-ascorbic acid and its esters, and each can be used alone. The inventors have found that the effect of improving rough skin is synergistically increased compared to the conventional method, and have completed the present invention based on this knowledge.

That is, the present invention is characterized by containing one or more selected from the group consisting of allantoin and its derivatives, and one or more selected from the group consisting of L-ascorbic acid and its esters. The purpose of the present invention is to provide cosmetics that have the following properties.

Hereinafter, the configuration of the present invention 1 will be explained in detail.

(J,;: 7./, , -li Allantoin used in the present invention has the following structural formula.

Furthermore, examples of derivatives of allantoin include dihydroxyaluminum allantoinate, chlorohydroxyaluminum ala/toinate, and the like.

In the present invention, one or more of these allantoin and its derivatives are appropriately selected and blended.

The blending amount is generally 0.001 to 5.0% by weight (hereinafter not simply referred to as %), preferably 0.05 to 3.0%.
It is. If it is less than 0.001%, the effect of the present invention will not be exhibited, and if it exceeds 5.0%, it is not only unnecessary for the skin (it is also unfavorable in terms of product manufacturing process and safety).

The ascorbic acid used in the present invention is generally referred to as vitamin C, and due to its strong reducing action, it has a cellular respiration action, an enzyme activation action, a collagen formation action, and also has a melanin reduction action. Examples of L-ascorbic acid-poor ster include mono-ascorbic acid monoalkyl esters such as L-ascorbic acid mo/stearate, L-ascorbic acid monopalmitate, and L-ascorbic acid monooleate; acid ester, L-ascorbic acid-2-sulfuric acid monoascorbic acid modiester derivative, L-ascorbic acid distearate, L-ascorbic acid dipalmitate, L-ascorbic acid dipalmitate,
- mono-ascorbic acid dialkyl esters such as ascorbic acid dioleate, mono-ascorbyl/acid diester derivatives such as L-ascorbic acid silicate ester, L-
-Ascorbic acid trisderate, L-ascorbyl
il) Trialkyl esters such as dipalmitate and L-ascorbic acid triolate, ascorbyl:/@) IJ ester derivatives such as L-ascorbic acid triphosphate, and the like. In the present invention, one or more of the above-mentioned monoascorbic acid and its esters are appropriately selected and blended.

The blending amount is generally 0.001% or more, and about 10.0% of P is sufficient to exhibit the effects of the present invention.

In addition to the above-mentioned essential ingredients, the cosmetics of the present invention contain surfactants, oils, humectants, ultraviolet absorbers, algols, chelating agents, N pHall modifiers, preservatives, thickening agents, pigments, fragrances, and other commonly used cosmetics. Components used in the preparation can be blended as appropriate. Of course, these must be within a range that does not impair the effects of the present invention.

The cosmetics of the present invention have an excellent effect on improving rough skin, and can be used not only for skin cosmetics such as nutritional creams, hand creams, body creams, milks/liquids, lotions, and packs, but also for hair cosmetics, especially scalp cosmetics. It can also be used as a material for cracks in winter,
Suitable for caring for chapped skin, rough skin, rough skin after shaving, rough hands, and scalp damaged by dyed hair or perms.

Next, the effect of the cosmetics of the present invention on improving rough skin will be explained with reference to Examples. The present invention is not limited thereby. The blending amount is in weight%.

(Leaving space below) Test method for improving effect on rough skin (test method) Example 1, Comparative Example 2, and Comparative Example 3 were tested using 24 women aged 20 to 40 who suffer from rough skin in winter as subjects. The subjects were divided into groups, with 8 people in each group. Usage period is winter 2
For a week, the cosmetic composition of Comparative Example 1 was applied to one cheek, and the cosmetic composition of Example 1, Comparative Example 2 or 3 of each group was applied to the other cheek at least twice a day, in the morning and evening.

(Measurement and judgment method) Measurement and judgment were carried out by the following method on the day after the two-week application was completed.

■ Evapolymeter Epl (Sweden 5erv
oMed, Inc.).

As for the actual judgment TWl, the larger the value, the less severe the skin roughness.

■By collecting skin replicas using silicone resin and observing them under a stereomicroscope, we investigated the surface morphology of the skin, which is closely related to the appearance of the skin.

Book judgment It has become.

Comparative Examples 1 to 3 and Example 1'' (Production method) ■■■ and ■ are dissolved in [phase]. Separately 70℃
■■■■■ [phase] and ■ dissolved in the were added and mixed, and 0 was added thereto and emulsified in a Homo Miki No. to obtain the cream of Example 1. Comparative Examples 1 to 3 were also produced in the same manner as Example 1. The results are shown in Table 1. Note that the numbers in the table represent the number of subjects judged for that item.

(Result).

As is clear from Table 1, the cosmetic of the present invention is several times more effective against skin irritation than the cosmetic containing allantoin and L-ascorbic acid alone, and these drugs act synergistically. It has been proven that it is working.

Example 2 Lotion ■ Glycerin 3.0 ■ Propylene glycol 4.0 ■ Ethanol 8.0 0 Polyoxyethylene (20 mol) 0.5 Oleyl alcohol ■ L-Ascorbic acid monostearate 0.001 ■
L-ascorbic acid tristearate 0.05 ■Allantoin 0.05 ■Dihydroxyaluminum ara/toinate 0.0
01 ■ Methylparaben 0.1 [Phase] Citric acid 0.001 ■ Sodium citrate 0.1 @Fragrance 0.05 [Phase] Ion exchange water 84.147 (Production method) [Phase], ■■■■■ [ Phase] and ■ are added and dissolved at room temperature (Part A). Add ■■■ and @ to ■ and dissolve at room temperature (Part B). A lotion was obtained by adding Part B to Part A.

Example 3 Scalp treatment ■Liquid paraffin 15.0 ■Vaseline 2.0 ■Cetanol 2.0 ■Polyethylene glycol 1500 7.0■Stearic acid 2.5 or'0E(0) Sorbitan monostearate 1.0
■ Glyceryl monostearate 1.0 ■ Caustic potash 1.0 ■ L-ascorbyl/acid monopalmitate 0.1 [phase]
Allantoin 0.05 ■Dihydroxy aluminum ara/toine) 0.0
010 Quinoline Yellow am [Phase] Brilliant Blue Rapid [Phase] Fragrance 0.5 [Phase] Ion exchange water (17,099 [Phase] Ethylparaben 0.05 (Production method) [Phase] ■■ [Phase] ■ Heat and dissolve @ and [phase] 70
Keep at ℃ (Part A). Mix other ingredients, heat and dissolve
Keep at 0°C (Part B). Part B was added to Part A, mixed by stirring, and then emulsified using a homomixer. Stir after emulsification 3
It was cooled to 0°C to obtain a milky scalp treatment.

Example 4 Emulsion ■Stearic acid 2.5 ■Cetyl alcohol 1.5 ■Vaseline 5.0 ■Liquid paraffin 10.0 ■Polyoxyethylene (10 mol) 2.0 monooleic acid ester ■Polyethylene glycol 1500 3.00 tri Ethanolamine 1.0 ■L-Asterulpic acid monophosphate 0.5 ■Ara/Toin 0.5 [Phase] Ion-exchanged water ? 3.45 ■Fragrance 0.5 0 Methylparaben 0.05 (Production method) Add ■■■ and ■ to [phase], heat and dissolve, and keep at 70°C (Part A). Mix other ingredients and heat to melt at 70°
Keep it at C (Part B). Part B was added to part A for preliminary emulsification, and the mixture was uniformly emulsified using a homomixer. After emulsification, the mixture was cooled to 30° C. while stirring to obtain a milky lotion.

Example 5 Back vinyl acetate resin emulsion 15.0 Polyvinyl alcohol 1010 Olive oil 5.0 Glycerin 5.0 Titanium oxide 8.0 Kaori 7 7.0 Sothorium hexametaphosphate 0.05 Edyl alcohol 5.0 Ion exchange water 33.45 Fragrance 0.3 Ethyl paraoxybenzoate 0.2 Allantoy/5・O L-ascorbine r! ie,.

(Manufacturing method) Polyvinyl alcohol is moistened with a portion of ethyl alcohol, added to ion-exchanged water in which titanium oxide, kaolin, and sodium hexametaphosphate are dispersed, heated to 70° C., and stirred to uniformly disperse.

To this, add glycerin, vinyl acetate resin emulsion, fragrance dissolved in the remainder of ethyl alcohol, ethyl benzoate, and olive oil, stir well to make a uniform paste, and add some ion-exchanged water. Dissolved allantoin, I,-ascorbic acid was gradually added to obtain ivy.

Ihi 11) of Examples 2 to 5 thus obtained:
li) were all excellent in improving effects on rough skin.

Applicant: Shiseido Co., Ltd.

Claims (1)

[Claims] A cosmetic containing one or more selected from the group consisting of allantoin and its derivatives, and one or more selected from the group consisting of L-ascorbic acid and its esters.