JPS61148198A - 新規トリペプチド化合物および甘味剤 - Google Patents

新規トリペプチド化合物および甘味剤

Info

Publication number
JPS61148198A
JPS61148198A JP59271478A JP27147884A JPS61148198A JP S61148198 A JPS61148198 A JP S61148198A JP 59271478 A JP59271478 A JP 59271478A JP 27147884 A JP27147884 A JP 27147884A JP S61148198 A JPS61148198 A JP S61148198A
Authority
JP
Japan
Prior art keywords
methyl ester
aspartyl
amino acid
ester
phenylalanine methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP59271478A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0533718B2 (enExample
Inventor
Tadashi Takemoto
正 竹本
Toyohito Tsuchiya
豊人 土屋
Toshihide Yugawa
湯川　利秀
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Priority to JP59271478A priority Critical patent/JPS61148198A/ja
Priority to US06/794,788 priority patent/US4780528A/en
Priority to EP85308208A priority patent/EP0186292B1/en
Priority to DE8585308208T priority patent/DE3577711D1/de
Priority to CA000495361A priority patent/CA1292838C/en
Publication of JPS61148198A publication Critical patent/JPS61148198A/ja
Publication of JPH0533718B2 publication Critical patent/JPH0533718B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0819—Tripeptides with the first amino acid being acidic
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C07K5/0823—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Pro-amino acid; Derivatives thereof
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/801—Peptide sweetners

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Peptides Or Proteins (AREA)
  • Seasonings (AREA)
JP59271478A 1984-12-22 1984-12-22 新規トリペプチド化合物および甘味剤 Granted JPS61148198A (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP59271478A JPS61148198A (ja) 1984-12-22 1984-12-22 新規トリペプチド化合物および甘味剤
US06/794,788 US4780528A (en) 1984-12-22 1985-11-04 Tripeptides and sweetening agents containing the same
EP85308208A EP0186292B1 (en) 1984-12-22 1985-11-12 Tripeptides and sweetening agents containing the same
DE8585308208T DE3577711D1 (de) 1984-12-22 1985-11-12 Tripeptide und deren suesstoffe.
CA000495361A CA1292838C (en) 1984-12-22 1985-11-14 Tripeptides and sweetening agents containing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59271478A JPS61148198A (ja) 1984-12-22 1984-12-22 新規トリペプチド化合物および甘味剤

Publications (2)

Publication Number Publication Date
JPS61148198A true JPS61148198A (ja) 1986-07-05
JPH0533718B2 JPH0533718B2 (enExample) 1993-05-20

Family

ID=17500596

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59271478A Granted JPS61148198A (ja) 1984-12-22 1984-12-22 新規トリペプチド化合物および甘味剤

Country Status (5)

Country Link
US (1) US4780528A (enExample)
EP (1) EP0186292B1 (enExample)
JP (1) JPS61148198A (enExample)
CA (1) CA1292838C (enExample)
DE (1) DE3577711D1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6267098A (ja) * 1985-09-18 1987-03-26 Ajinomoto Co Inc 新規トリペプチド化合物及び甘味剤

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU201094B (en) * 1986-01-23 1990-09-28 Pfizer Process for producing immunostimulant acyltripeptides and pharmaceutical compositions comprising same as active ingredient
IT1231342B (it) * 1989-08-28 1991-11-28 Prodotti Antibiotici Spa Derivati peptidici farmacologicamente attivi e preparazioni farmaceutiche che li contengono
EP0445606B1 (en) * 1990-02-27 1997-01-22 The Agency of Industrial Science and Technology Novel oligopeptides, pharmaceutical composition and food containing the same, and use of oligopeptides
SG170767A1 (en) * 2005-12-23 2011-05-30 Zealand Pharma As Modified lysine-mimetic compounds
EP2468724B1 (en) * 2006-12-21 2015-11-18 Zealand Pharma A/S Synthesis of pyrrolidine compounds
WO2018202865A1 (en) 2017-05-05 2018-11-08 Zealand Pharma A/S Gap junction intercellular communication modulators and their use for the treatment of diabetic eye disease
US20240315296A1 (en) * 2021-07-01 2024-09-26 Cj Cheiljedang Corporation Peptide compounds for flavor modulating

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA787917A (en) * 1968-06-18 Vogler Karl Peptides and process for the manufacture thereof
GB1042488A (en) * 1964-09-02 1966-09-14 Ici Ltd Tripeptide derivatives
DE1692768C3 (de) * 1968-02-16 1973-10-25 G.D. Searle & Co., Chicago, Ill. (V.St.A.) Süßstoff
BE791544A (fr) * 1971-11-19 1973-05-17 Stamicarbon Preparation d'esters alkyliques de dipeptide
US4017472A (en) * 1973-03-05 1977-04-12 G. D. Searle & Co. Process for isolation of aspartyl dipeptide esters
US4127534A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel tripeptides, intermediates therefor and pharmaceutical compositions and methods employing said tripeptides
HU185263B (en) * 1981-06-12 1984-12-28 Richter Gedeon Vegyeszet Process for producing peptides effective on the immuncontroll analogous with the tp5
US4491541A (en) * 1982-11-10 1985-01-01 Farmitalia Carlo Erba Peptides
IT1172391B (it) * 1983-12-23 1987-06-18 Polifarma Spa Composti tirpeptidici contenenti acido piroglutaminico e triptofano,procedimentio di produzione ed applicazioni terapeutiche

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6267098A (ja) * 1985-09-18 1987-03-26 Ajinomoto Co Inc 新規トリペプチド化合物及び甘味剤

Also Published As

Publication number Publication date
JPH0533718B2 (enExample) 1993-05-20
US4780528A (en) 1988-10-25
DE3577711D1 (de) 1990-06-21
EP0186292B1 (en) 1990-05-16
EP0186292A3 (en) 1988-08-03
EP0186292A2 (en) 1986-07-02
CA1292838C (en) 1991-12-03

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