JPS6036479A - １，３−ジオキサン誘導体、本化合物を有効成分とする抗潰瘍剤及びその製造方法 - Google Patents

１，３−ジオキサン誘導体、本化合物を有効成分とする抗潰瘍剤及びその製造方法

Info

Publication number
JPS6036479A
JPS6036479A JP58144709A JP14470983A JPS6036479A JP S6036479 A JPS6036479 A JP S6036479A JP 58144709 A JP58144709 A JP 58144709A JP 14470983 A JP14470983 A JP 14470983A JP S6036479 A JPS6036479 A JP S6036479A
Authority
JP
Japan
Prior art keywords
alkyl group
general formula
formula
group
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP58144709A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0425270B2 (enExample
Inventor
Takeshi Tomiyama
剛 冨山
Itaru Tomiyama
冨山　格
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kotobuki Seiyaku Co Ltd
Original Assignee
Kotobuki Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kotobuki Seiyaku Co Ltd filed Critical Kotobuki Seiyaku Co Ltd
Priority to JP58144709A priority Critical patent/JPS6036479A/ja
Priority to US06/636,143 priority patent/US4631292A/en
Priority to GB08419595A priority patent/GB2145410B/en
Priority to FR8412458A priority patent/FR2550531B1/fr
Priority to DE19843429227 priority patent/DE3429227A1/de
Publication of JPS6036479A publication Critical patent/JPS6036479A/ja
Publication of JPH0425270B2 publication Critical patent/JPH0425270B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/08—1,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP58144709A 1983-08-08 1983-08-08 １，３−ジオキサン誘導体、本化合物を有効成分とする抗潰瘍剤及びその製造方法 Granted JPS6036479A (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP58144709A JPS6036479A (ja) 1983-08-08 1983-08-08 １，３−ジオキサン誘導体、本化合物を有効成分とする抗潰瘍剤及びその製造方法
US06/636,143 US4631292A (en) 1983-08-08 1984-07-31 1,3-dioxane derivatives, method of their synthesis and anti-peptic ulcer agent
GB08419595A GB2145410B (en) 1983-08-08 1984-08-01 1,3-dioxane derivatives
FR8412458A FR2550531B1 (fr) 1983-08-08 1984-08-07 Derives du 1,3-dioxanne, procede pour leur synthese et agent anti-ulcere peptique
DE19843429227 DE3429227A1 (de) 1983-08-08 1984-08-08 1,3-dioxanderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58144709A JPS6036479A (ja) 1983-08-08 1983-08-08 １，３−ジオキサン誘導体、本化合物を有効成分とする抗潰瘍剤及びその製造方法

Publications (2)

Publication Number Publication Date
JPS6036479A true JPS6036479A (ja) 1985-02-25
JPH0425270B2 JPH0425270B2 (enExample) 1992-04-30

Family

ID=15368460

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58144709A Granted JPS6036479A (ja) 1983-08-08 1983-08-08 １，３−ジオキサン誘導体、本化合物を有効成分とする抗潰瘍剤及びその製造方法

Country Status (5)

Country Link
US (1) US4631292A (enExample)
JP (1) JPS6036479A (enExample)
DE (1) DE3429227A1 (enExample)
FR (1) FR2550531B1 (enExample)
GB (1) GB2145410B (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015537055A (ja) * 2012-12-18 2015-12-24 ディーエスエム アイピー アセッツ ビー．ブイ． 組み合わされた不斉水素化によって特定の生成物を定量的に得るためのｅ／ｚ異性体の混合物の使用
JP2016505568A (ja) * 2012-12-18 2016-02-25 ディーエスエム アイピー アセッツ ビー．ブイ． 不斉水素化および異性化を組み合わせることによって特定の生成物を定量的に得るためのｅ／ｚ異性体の混合物の使用
JP2016506393A (ja) * 2012-12-18 2016-03-03 ディーエスエム アイピー アセッツ ビー．ブイ． ６，１０，１４−トリメチルペンタデカ−５，９，１３−トリエン−２−オンまたは６，１０，１４−トリメチルペンタデカ−５，９−ジエン−２−オンから調製した（６ｒ，１０ｒ）−６，１０，１４−トリメチルペンタデカン−２−オン

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0282643A3 (en) * 1986-11-22 1990-08-22 The Green Cross Corporation Use of pharmaceutical compositions comprising cyclohexane derivatives in the treatment or prevention of peptic ulcers
CN1922125B (zh) * 2004-02-25 2010-12-01 出光兴产株式会社 烷基缩醛化合物、制备该化合物的方法以及润滑油组合物
DE102007010077B4 (de) 2007-02-28 2010-04-08 RUHR-UNIVERSITäT BOCHUM [1,3]-Dioxane zur Modulation von GABAa-Rezeptoren
DK2595948T3 (da) * 2010-07-20 2019-10-21 Leo Laboratories Ltd Fremgangsmåde til fremstilling af ingenol-3-angelat
EP4190308B1 (de) 2021-12-06 2025-07-23 Marome GmbH Schlafduft sowie herstellung und verwendung von diesem

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5088246A (enExample) * 1973-11-30 1975-07-15

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB702206A (en) * 1950-03-31 1954-01-13 Anglo Iranian Oil Co Ltd Improvements in or relating to the production of dialdehydes and derivatives thereof
US2729650A (en) * 1950-03-31 1956-01-03 British Petroleum Co Production of dialdehydes and derivatives thereof
GB715744A (en) * 1950-12-27 1954-09-22 Anglo Iranian Oil Co Ltd Improvements in or relating to the production of aldehydes and acetals
US2691026A (en) * 1951-03-30 1954-10-05 Atlas Powder Co Process for the preparation of acetal esters
US3010945A (en) * 1957-09-10 1961-11-28 Du Pont Polymerizing vinyl cyclic acetals with cobaltous salts of dicarboxylic acid half-esters
NL243096A (enExample) * 1958-09-09 1900-01-01
GB948084A (en) * 1960-03-26 1964-01-29 Consortium Elektrochem Ind Process for the manufacture of cyclic vinyl ketals
US3326746A (en) * 1962-09-04 1967-06-20 Lever Brothers Ltd 1, 3-dioxane cleaning compositions
GB1178988A (en) * 1966-08-12 1970-01-28 Lummus Co Production of Acetals and Ketals
CH547796A (de) * 1970-02-24 1974-04-11 Monsanto Co Verfahren zur herstellung von 1,3-dioxolanen und -dioxanen.
SU411086A1 (enExample) * 1971-09-27 1974-01-15
FR2235940B1 (enExample) * 1973-07-06 1978-12-01 Basf Ag
GB1448458A (en) * 1973-11-21 1976-09-08 Allen & Hanburys Ltd 1,3-dioxan derivatives and pharmaceutical compositions thereof
DE2533048A1 (de) * 1975-07-24 1977-02-17 Henkel & Cie Gmbh Entzuendungshemmer fuer kosmetische praeparationen
US4003918A (en) * 1975-12-15 1977-01-18 Celanese Corporation Production of 2-vinyl-1,3-dioxane compounds
US4096192A (en) * 1976-03-30 1978-06-20 E. I. Du Pont De Nemours And Company Process for the preparation of 2-methyl-1,3-propanediol
US4105677A (en) * 1976-04-29 1978-08-08 Celanese Corporation Production of tetrahydrofuran
SU688501A1 (ru) * 1978-04-05 1979-09-30 Уфимский Нефтяной Институт Способ получени м-диоксанов
DE3016007A1 (de) * 1980-04-25 1981-11-12 Henkel KGaA, 4000 Düsseldorf Verwendung substituierter 2-(1-methylbutyl)-1,3-dioxane als riechstoffe sowie diese enthaltende riechstoffkompositionen
DE3017540A1 (de) * 1980-05-08 1981-11-12 Bayer Ag, 5090 Leverkusen Cyclische ketale, ihre herstellung und verwendung
JPS585162B2 (ja) * 1980-12-10 1983-01-29 理化学研究所 殺ダニ剤
CA1239349A (en) * 1983-10-10 1988-07-19 Eberhard F. Gottwald Pharmaceutical composition containing cimetidine

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5088246A (enExample) * 1973-11-30 1975-07-15

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015537055A (ja) * 2012-12-18 2015-12-24 ディーエスエム アイピー アセッツ ビー．ブイ． 組み合わされた不斉水素化によって特定の生成物を定量的に得るためのｅ／ｚ異性体の混合物の使用
JP2016505568A (ja) * 2012-12-18 2016-02-25 ディーエスエム アイピー アセッツ ビー．ブイ． 不斉水素化および異性化を組み合わせることによって特定の生成物を定量的に得るためのｅ／ｚ異性体の混合物の使用
JP2016506393A (ja) * 2012-12-18 2016-03-03 ディーエスエム アイピー アセッツ ビー．ブイ． ６，１０，１４−トリメチルペンタデカ−５，９，１３−トリエン−２−オンまたは６，１０，１４−トリメチルペンタデカ−５，９−ジエン−２−オンから調製した（６ｒ，１０ｒ）−６，１０，１４−トリメチルペンタデカン−２−オン

Also Published As

Publication number Publication date
GB2145410A (en) 1985-03-27
GB2145410B (en) 1987-11-25
DE3429227A1 (de) 1985-02-21
JPH0425270B2 (enExample) 1992-04-30
GB8419595D0 (en) 1984-09-05
FR2550531B1 (fr) 1988-03-18
FR2550531A1 (fr) 1985-02-15
US4631292A (en) 1986-12-23

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