JPS60192703A - 少なくとも1個の遊離ホルミル基を有する高分子化合物 - Google Patents

少なくとも1個の遊離ホルミル基を有する高分子化合物

Info

Publication number
JPS60192703A
JPS60192703A JP59258138A JP25813884A JPS60192703A JP S60192703 A JPS60192703 A JP S60192703A JP 59258138 A JP59258138 A JP 59258138A JP 25813884 A JP25813884 A JP 25813884A JP S60192703 A JPS60192703 A JP S60192703A
Authority
JP
Japan
Prior art keywords
group
conjugate
compound
polymer compound
physiologically active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP59258138A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6353201B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html
Inventor
Hiroyoshi Takahashi
啓悦 高橋
Nobuo Ueda
上田 信夫
Masaaki Hazue
葉杖 正昭
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NIPPON MEJIFUIJITSUKUSU KK
Nihon Medi Physics Co Ltd
Original Assignee
NIPPON MEJIFUIJITSUKUSU KK
Nihon Medi Physics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/558,333 external-priority patent/US4666697A/en
Application filed by NIPPON MEJIFUIJITSUKUSU KK, Nihon Medi Physics Co Ltd filed Critical NIPPON MEJIFUIJITSUKUSU KK
Publication of JPS60192703A publication Critical patent/JPS60192703A/ja
Publication of JPS6353201B2 publication Critical patent/JPS6353201B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP59258138A 1983-12-05 1984-12-05 少なくとも1個の遊離ホルミル基を有する高分子化合物 Granted JPS60192703A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/558,333 US4666697A (en) 1982-12-08 1983-12-05 Radioactive diagnostic agent
US558333 1995-11-15

Publications (2)

Publication Number Publication Date
JPS60192703A true JPS60192703A (ja) 1985-10-01
JPS6353201B2 JPS6353201B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1988-10-21

Family

ID=24229141

Family Applications (3)

Application Number Title Priority Date Filing Date
JP59258138A Granted JPS60192703A (ja) 1983-12-05 1984-12-05 少なくとも1個の遊離ホルミル基を有する高分子化合物
JP59258139A Granted JPS60186502A (ja) 1983-12-05 1984-12-05 放射性医薬品とその調製用高分子化合物
JP62268981A Granted JPS63225601A (ja) 1983-12-05 1987-10-24 放射性医薬品調製用高分子化合物

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP59258139A Granted JPS60186502A (ja) 1983-12-05 1984-12-05 放射性医薬品とその調製用高分子化合物
JP62268981A Granted JPS63225601A (ja) 1983-12-05 1987-10-24 放射性医薬品調製用高分子化合物

Country Status (1)

Country Link
JP (3) JPS60192703A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5672334A (en) * 1991-01-16 1997-09-30 Access Pharmaceuticals, Inc. Invivo agents comprising cationic metal chelators with acidic saccharides and glycosaminoglycans
US5707604A (en) * 1986-11-18 1998-01-13 Access Pharmaceuticals, Inc. Vivo agents comprising metal-ion chelates with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles
US6106866A (en) * 1995-07-31 2000-08-22 Access Pharmaceuticals, Inc. In vivo agents comprising cationic drugs, peptides and metal chelators with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles, including tumor sites
US10436790B2 (en) 2011-09-28 2019-10-08 Waters Technologies Corporation Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals
CN103842818B (zh) 2011-09-28 2018-09-21 沃特世科技公司 具有增强的ms信号的聚糖和其它生物分子的快速荧光标记
US11352325B2 (en) 2011-09-28 2022-06-07 Waters Technologies Corporation Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals
JP6099055B2 (ja) * 2014-05-09 2017-03-22 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル 変性病変の診断のためのリガンドとしてのフコイダン
DK3213056T3 (da) 2014-10-30 2020-09-28 Waters Technologies Corp Fremgangsmåder til hurtig forberedelse af mærkede glycosylaminer og til analyse af glykosylerede biomolekyler, som giver samme baggrund
WO2016077548A1 (en) * 2014-11-13 2016-05-19 Waters Technologies Corporation Methods for liquid chromatography calibration for rapid labeled n-glycans
EP3472132A4 (en) 2016-06-21 2020-01-15 Waters Technologies Corporation FLUORESCENCE LABELING OF GLYCANS AND OTHER BIOMOLECULES BY REDUCING AMINATION FOR IMPROVED MASS SPECTROMETRY SIGNALS
CN109642906A (zh) 2016-06-21 2019-04-16 沃特世科技公司 对用两亲强碱性部分改性的聚糖进行电喷雾电离的方法
EP3479103B1 (en) 2016-07-01 2022-04-20 Waters Technologies Corporation Methods for the rapid preparation of labeled glycosylamines from complex matrices using molecular weight cut off filtration and on-filter deglycosylation

Also Published As

Publication number Publication date
JPS641449B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1989-01-11
JPS6353201B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1988-10-21
JPS60186502A (ja) 1985-09-24
JPS63225601A (ja) 1988-09-20
JPH0548761B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-07-22

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