JPS596868B2 - 新規イソキノリン誘導体の製造方法 - Google Patents

新規イソキノリン誘導体の製造方法

Info

Publication number
JPS596868B2
JPS596868B2 JP49102862A JP10286274A JPS596868B2 JP S596868 B2 JPS596868 B2 JP S596868B2 JP 49102862 A JP49102862 A JP 49102862A JP 10286274 A JP10286274 A JP 10286274A JP S596868 B2 JPS596868 B2 JP S596868B2
Authority
JP
Japan
Prior art keywords
group
formula
dimethyl
hydrogen atom
tables
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP49102862A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5050381A (en, 2012
Inventor
クツテル エ−ベルハルト
アウシユテル ホルカルト
エ−ベルライン ボルフガンク
ハイデル ヨアヒム
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2345422A external-priority patent/DE2345422C2/de
Priority claimed from DE19732345423 external-priority patent/DE2345423A1/de
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of JPS5050381A publication Critical patent/JPS5050381A/ja
Publication of JPS596868B2 publication Critical patent/JPS596868B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
JP49102862A 1973-09-08 1974-09-06 新規イソキノリン誘導体の製造方法 Expired JPS596868B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE2345422A DE2345422C2 (de) 1973-09-08 1973-09-08 Substituierte Isochinolyl-arylpiperazine diese enthaltende Arzneimittel sowie Verfahren zu deren Herstellung
DE2345423 1973-09-08
DE19732345423 DE2345423A1 (de) 1973-09-08 1973-09-08 Neue substituierte phenylaethylaminderivate, deren saeureadditionssalze, diese enthaltende arzneimittel sowie verfahren zu deren herstellung
DE2345422 1973-09-08

Publications (2)

Publication Number Publication Date
JPS5050381A JPS5050381A (en, 2012) 1975-05-06
JPS596868B2 true JPS596868B2 (ja) 1984-02-15

Family

ID=25765764

Family Applications (1)

Application Number Title Priority Date Filing Date
JP49102862A Expired JPS596868B2 (ja) 1973-09-08 1974-09-06 新規イソキノリン誘導体の製造方法

Country Status (26)

Country Link
US (1) US3948898A (en, 2012)
JP (1) JPS596868B2 (en, 2012)
AT (1) AT330777B (en, 2012)
BG (2) BG22390A3 (en, 2012)
CA (1) CA1025869A (en, 2012)
CH (2) CH605779A5 (en, 2012)
CS (1) CS185660B2 (en, 2012)
DD (1) DD115122A5 (en, 2012)
DK (1) DK137124C (en, 2012)
ES (3) ES429473A1 (en, 2012)
FI (1) FI52219C (en, 2012)
FR (1) FR2242979B1 (en, 2012)
GB (1) GB1446791A (en, 2012)
HK (1) HK4180A (en, 2012)
HU (1) HU167869B (en, 2012)
IE (1) IE40742B1 (en, 2012)
IL (1) IL45609A (en, 2012)
MY (1) MY8100330A (en, 2012)
NL (1) NL176363C (en, 2012)
NO (1) NO140978C (en, 2012)
PH (1) PH12918A (en, 2012)
PL (1) PL91712B1 (en, 2012)
RO (1) RO63655A (en, 2012)
SE (1) SE424863B (en, 2012)
SU (2) SU545256A3 (en, 2012)
YU (1) YU39928B (en, 2012)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6312877U (en, 2012) * 1986-03-05 1988-01-27

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2639718C2 (de) * 1976-09-03 1987-03-05 Dr. Karl Thomae Gmbh, 7950 Biberach 1-[6,7-Dimethoxy-3,4-dihydro-2H-isochinolin-1-on-2-yl]-3-[N-methyl-N-(2-(3,4-dimethoxy-phenyl)-äthyl)-amino]-propan, dessen physiologisch verträgliche Säureadditionssalze und diese Verbindungen enthaltende Arzneimittel
DE2702600A1 (de) * 1977-01-22 1978-07-27 Thomae Gmbh Dr K Neue aminoalkoxyphenyl-derivate
US4619930A (en) * 1985-01-16 1986-10-28 Bristol-Myers Company Antipsychotic cyclic imide derivatives of 2-(4-butylpiperazin-1-yl)pyridines, compositions and use
US4876256A (en) * 1988-04-29 1989-10-24 Merck & Co., Inc. Alkylpiperazinylpyridines as hypoglycemic agents
US5169948A (en) * 1991-05-22 1992-12-08 American Home Products Corporation Process and intermediates for the preparation of spiro[isoquinoline-4(1H),3-pyrrolidine]1,2,3,5 (2H)-tetrones which are useful as aldose reductase inhibitors
SE9303274D0 (sv) * 1993-10-07 1993-10-07 Astra Ab Novel phenylethyl and phenylproplamines
DE69826883T2 (de) 1997-10-27 2005-02-03 Neurosearch A/S Heteroaryl diazacycloalkane als cholinergische ligande für nikotin-acetylcholin-rezeptoren
US20040152710A1 (en) * 2002-10-15 2004-08-05 Deecher Darlene Coleman Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms
EP1844033B1 (de) * 2005-01-28 2011-07-27 Boehringer Ingelheim Pharma GmbH & Co. KG Verfahren zur herstellung von isochroman und derivaten davon
US8927546B2 (en) 2006-02-28 2015-01-06 Dart Neuroscience (Cayman) Ltd. Therapeutic piperazines
JP2009528363A (ja) 2006-02-28 2009-08-06 ヘリコン セラピューティクス，インコーポレイテッド Ｐｄｅ４インヒビターとしての治療用ピペラジン
WO2023288039A1 (en) * 2021-07-16 2023-01-19 Denali Therapeutics Inc. Compounds, compositions and methods

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1185934A (en) * 1967-06-28 1970-03-25 Pfizer & Co C Derivatives of 1,3(2H,4H)-Dioxoisoquinoline and preparation thereof
SE368009B (en, 2012) * 1971-09-16 1974-06-17 Kabi Ab
GB1424348A (en) * 1972-11-30 1976-02-11 Wyeth John & Brother Ltd Isoquinoline derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6312877U (en, 2012) * 1986-03-05 1988-01-27

Also Published As

Publication number Publication date
SU538664A3 (ru) 1976-12-05
ES429473A1 (es) 1976-09-01
AT330777B (de) 1976-07-26
NL7411843A (nl) 1975-03-11
HU167869B (en, 2012) 1975-12-25
PH12918A (en) 1979-10-10
DK137124C (da) 1978-06-26
ES433959A1 (es) 1976-11-16
HK4180A (en) 1980-02-08
CS185660B2 (en) 1978-10-31
CH605779A5 (en, 2012) 1978-10-13
NL176363C (nl) 1985-04-01
FI52219C (fi) 1977-07-11
NO140978C (no) 1979-12-19
MY8100330A (en) 1981-12-31
FR2242979B1 (en, 2012) 1978-02-03
US3948898A (en) 1976-04-06
IE40742L (en) 1975-03-08
BG22390A3 (bg) 1977-02-20
PL91712B1 (en, 2012) 1977-03-31
SE424863B (sv) 1982-08-16
NO743220L (en, 2012) 1975-04-07
SE7411312L (en, 2012) 1975-03-10
GB1446791A (en) 1976-08-18
AU7302374A (en) 1976-03-11
YU239174A (en) 1982-06-30
IL45609A0 (en) 1974-11-29
IE40742B1 (en) 1979-08-15
DK137124B (da) 1978-01-23
ES433958A1 (es) 1976-11-16
YU39928B (en) 1985-06-30
CA1025869A (en) 1978-02-07
DK472774A (en, 2012) 1975-05-05
FR2242979A1 (en, 2012) 1975-04-04
CH605778A5 (en, 2012) 1978-10-13
FI52219B (en, 2012) 1977-03-31
NO140978B (no) 1979-09-10
JPS5050381A (en, 2012) 1975-05-06
DD115122A5 (en, 2012) 1975-09-12
FI246574A7 (en, 2012) 1975-03-09
IL45609A (en) 1977-07-31
RO63655A (fr) 1978-10-15
NL176363B (nl) 1984-11-01
SU545256A3 (ru) 1977-01-30
ATA651474A (de) 1975-10-15
BG26195A4 (bg) 1979-02-15

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