ES433959A1 - Procedimiento para la preparacion de nuevos derivados de isoquinoleina. - Google Patents

Procedimiento para la preparacion de nuevos derivados de isoquinoleina.

Info

Publication number
ES433959A1
ES433959A1 ES433959A ES433959A ES433959A1 ES 433959 A1 ES433959 A1 ES 433959A1 ES 433959 A ES433959 A ES 433959A ES 433959 A ES433959 A ES 433959A ES 433959 A1 ES433959 A1 ES 433959A1
Authority
ES
Spain
Prior art keywords
phenyl
methoxy
hydrogen
salts
isoquinolines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES433959A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19732345423 external-priority patent/DE2345423A1/de
Priority claimed from DE2345422A external-priority patent/DE2345422C2/de
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES433959A1 publication Critical patent/ES433959A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
ES433959A 1973-09-08 1975-01-20 Procedimiento para la preparacion de nuevos derivados de isoquinoleina. Expired ES433959A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19732345423 DE2345423A1 (de) 1973-09-08 1973-09-08 Neue substituierte phenylaethylaminderivate, deren saeureadditionssalze, diese enthaltende arzneimittel sowie verfahren zu deren herstellung
DE2345422A DE2345422C2 (de) 1973-09-08 1973-09-08 Substituierte Isochinolyl-arylpiperazine diese enthaltende Arzneimittel sowie Verfahren zu deren Herstellung

Publications (1)

Publication Number Publication Date
ES433959A1 true ES433959A1 (es) 1976-11-16

Family

ID=25765764

Family Applications (3)

Application Number Title Priority Date Filing Date
ES429473A Expired ES429473A1 (es) 1973-09-08 1974-08-23 Procedimiento para la preparacion de nuevos derivados de isoquinoleina.
ES433959A Expired ES433959A1 (es) 1973-09-08 1975-01-20 Procedimiento para la preparacion de nuevos derivados de isoquinoleina.
ES433958A Expired ES433958A1 (es) 1973-09-08 1975-01-20 Procedimiento para la preparacion de nuevos derivados de isoquinoleina.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES429473A Expired ES429473A1 (es) 1973-09-08 1974-08-23 Procedimiento para la preparacion de nuevos derivados de isoquinoleina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES433958A Expired ES433958A1 (es) 1973-09-08 1975-01-20 Procedimiento para la preparacion de nuevos derivados de isoquinoleina.

Country Status (26)

Country Link
US (1) US3948898A (es)
JP (1) JPS596868B2 (es)
AT (1) AT330777B (es)
BG (2) BG22390A3 (es)
CA (1) CA1025869A (es)
CH (2) CH605778A5 (es)
CS (1) CS185660B2 (es)
DD (1) DD115122A5 (es)
DK (1) DK137124C (es)
ES (3) ES429473A1 (es)
FI (1) FI52219C (es)
FR (1) FR2242979B1 (es)
GB (1) GB1446791A (es)
HK (1) HK4180A (es)
HU (1) HU167869B (es)
IE (1) IE40742B1 (es)
IL (1) IL45609A (es)
MY (1) MY8100330A (es)
NL (1) NL176363C (es)
NO (1) NO140978C (es)
PH (1) PH12918A (es)
PL (1) PL91712B1 (es)
RO (1) RO63655A (es)
SE (1) SE424863B (es)
SU (2) SU545256A3 (es)
YU (1) YU39928B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2639718C2 (de) * 1976-09-03 1987-03-05 Dr. Karl Thomae Gmbh, 7950 Biberach 1-[6,7-Dimethoxy-3,4-dihydro-2H-isochinolin-1-on-2-yl]-3-[N-methyl-N-(2-(3,4-dimethoxy-phenyl)-äthyl)-amino]-propan, dessen physiologisch verträgliche Säureadditionssalze und diese Verbindungen enthaltende Arzneimittel
DE2702600A1 (de) * 1977-01-22 1978-07-27 Thomae Gmbh Dr K Neue aminoalkoxyphenyl-derivate
US4619930A (en) * 1985-01-16 1986-10-28 Bristol-Myers Company Antipsychotic cyclic imide derivatives of 2-(4-butylpiperazin-1-yl)pyridines, compositions and use
JPS6312877U (es) * 1986-03-05 1988-01-27
US4876256A (en) * 1988-04-29 1989-10-24 Merck & Co., Inc. Alkylpiperazinylpyridines as hypoglycemic agents
US5169948A (en) * 1991-05-22 1992-12-08 American Home Products Corporation Process and intermediates for the preparation of spiro[isoquinoline-4(1H),3-pyrrolidine]1,2,3,5 (2H)-tetrones which are useful as aldose reductase inhibitors
SE9303274D0 (sv) * 1993-10-07 1993-10-07 Astra Ab Novel phenylethyl and phenylproplamines
WO1999021834A1 (en) 1997-10-27 1999-05-06 Neurosearch A/S Heteroaryl diazacycloalkanes as cholinergic ligands at nicotinic acetylcholine receptors
US20040152710A1 (en) * 2002-10-15 2004-08-05 Deecher Darlene Coleman Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms
CA2595339C (en) * 2005-01-28 2014-08-19 Boehringer Ingelheim Pharma Gmbh & Co. Kg Method for producing isochromane and derivatives thereof
ES2462240T3 (es) * 2006-02-28 2014-05-22 Dart Neuroscience (Cayman) Ltd Piperazinas terapéuticas como inhibidores de PDE4
US8927546B2 (en) 2006-02-28 2015-01-06 Dart Neuroscience (Cayman) Ltd. Therapeutic piperazines
WO2023288039A1 (en) * 2021-07-16 2023-01-19 Denali Therapeutics Inc. Compounds, compositions and methods

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1185934A (en) * 1967-06-28 1970-03-25 Pfizer & Co C Derivatives of 1,3(2H,4H)-Dioxoisoquinoline and preparation thereof
SE368009B (es) * 1971-09-16 1974-06-17 Kabi Ab
GB1424348A (en) * 1972-11-30 1976-02-11 Wyeth John & Brother Ltd Isoquinoline derivatives

Also Published As

Publication number Publication date
FR2242979A1 (es) 1975-04-04
ATA651474A (de) 1975-10-15
GB1446791A (en) 1976-08-18
CS185660B2 (en) 1978-10-31
JPS596868B2 (ja) 1984-02-15
YU239174A (en) 1982-06-30
SE424863B (sv) 1982-08-16
ES429473A1 (es) 1976-09-01
FI52219B (es) 1977-03-31
NL7411843A (nl) 1975-03-11
ES433958A1 (es) 1976-11-16
YU39928B (en) 1985-06-30
IE40742L (en) 1975-03-08
RO63655A (fr) 1978-10-15
IL45609A (en) 1977-07-31
BG26195A4 (bg) 1979-02-15
CA1025869A (en) 1978-02-07
IL45609A0 (en) 1974-11-29
FR2242979B1 (es) 1978-02-03
DK137124B (da) 1978-01-23
BG22390A3 (bg) 1977-02-20
PL91712B1 (es) 1977-03-31
NO140978C (no) 1979-12-19
PH12918A (en) 1979-10-10
CH605779A5 (es) 1978-10-13
MY8100330A (en) 1981-12-31
IE40742B1 (en) 1979-08-15
DK137124C (da) 1978-06-26
HK4180A (en) 1980-02-08
NO743220L (es) 1975-04-07
NO140978B (no) 1979-09-10
DD115122A5 (es) 1975-09-12
NL176363B (nl) 1984-11-01
SU545256A3 (ru) 1977-01-30
SU538664A3 (ru) 1976-12-05
FI52219C (fi) 1977-07-11
FI246574A (es) 1975-03-09
CH605778A5 (es) 1978-10-13
DK472774A (es) 1975-05-05
NL176363C (nl) 1985-04-01
AT330777B (de) 1976-07-26
JPS5050381A (es) 1975-05-06
HU167869B (es) 1975-12-25
SE7411312L (es) 1975-03-10
AU7302374A (en) 1976-03-11
US3948898A (en) 1976-04-06

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