CS185660B2 - Process for preparing new 2-substituted 4,4-dimethyl-1,3-dioxo/2h,4h/isochinolines - Google Patents

Process for preparing new 2-substituted 4,4-dimethyl-1,3-dioxo/2h,4h/isochinolines

Info

Publication number
CS185660B2
CS185660B2 CS7400006150A CS615074A CS185660B2 CS 185660 B2 CS185660 B2 CS 185660B2 CS 7400006150 A CS7400006150 A CS 7400006150A CS 615074 A CS615074 A CS 615074A CS 185660 B2 CS185660 B2 CS 185660B2
Authority
CS
Czechoslovakia
Prior art keywords
isochinolines
dioxo
dimethyl
substituted
preparing new
Prior art date
Application number
CS7400006150A
Other languages
Czech (cs)
English (en)
Inventor
Eberhard Kutter
Volkard Austel
Wolfgang Eberlein
Joachim Heider
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2345422A external-priority patent/DE2345422C2/de
Priority claimed from DE19732345423 external-priority patent/DE2345423A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of CS185660B2 publication Critical patent/CS185660B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
CS7400006150A 1973-09-08 1974-09-06 Process for preparing new 2-substituted 4,4-dimethyl-1,3-dioxo/2h,4h/isochinolines CS185660B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2345422A DE2345422C2 (de) 1973-09-08 1973-09-08 Substituierte Isochinolyl-arylpiperazine diese enthaltende Arzneimittel sowie Verfahren zu deren Herstellung
DE19732345423 DE2345423A1 (de) 1973-09-08 1973-09-08 Neue substituierte phenylaethylaminderivate, deren saeureadditionssalze, diese enthaltende arzneimittel sowie verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
CS185660B2 true CS185660B2 (en) 1978-10-31

Family

ID=25765764

Family Applications (1)

Application Number Title Priority Date Filing Date
CS7400006150A CS185660B2 (en) 1973-09-08 1974-09-06 Process for preparing new 2-substituted 4,4-dimethyl-1,3-dioxo/2h,4h/isochinolines

Country Status (26)

Country Link
US (1) US3948898A (es)
JP (1) JPS596868B2 (es)
AT (1) AT330777B (es)
BG (2) BG26195A4 (es)
CA (1) CA1025869A (es)
CH (2) CH605779A5 (es)
CS (1) CS185660B2 (es)
DD (1) DD115122A5 (es)
DK (1) DK137124C (es)
ES (3) ES429473A1 (es)
FI (1) FI52219C (es)
FR (1) FR2242979B1 (es)
GB (1) GB1446791A (es)
HK (1) HK4180A (es)
HU (1) HU167869B (es)
IE (1) IE40742B1 (es)
IL (1) IL45609A (es)
MY (1) MY8100330A (es)
NL (1) NL176363C (es)
NO (1) NO140978C (es)
PH (1) PH12918A (es)
PL (1) PL91712B1 (es)
RO (1) RO63655A (es)
SE (1) SE424863B (es)
SU (2) SU545256A3 (es)
YU (1) YU39928B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2639718A1 (de) * 1976-09-03 1978-03-16 Thomae Gmbh Dr K Neue phenylaethylamine
DE2702600A1 (de) * 1977-01-22 1978-07-27 Thomae Gmbh Dr K Neue aminoalkoxyphenyl-derivate
US4619930A (en) * 1985-01-16 1986-10-28 Bristol-Myers Company Antipsychotic cyclic imide derivatives of 2-(4-butylpiperazin-1-yl)pyridines, compositions and use
JPS6312877U (es) * 1986-03-05 1988-01-27
US4876256A (en) * 1988-04-29 1989-10-24 Merck & Co., Inc. Alkylpiperazinylpyridines as hypoglycemic agents
US5169948A (en) * 1991-05-22 1992-12-08 American Home Products Corporation Process and intermediates for the preparation of spiro[isoquinoline-4(1H),3-pyrrolidine]1,2,3,5 (2H)-tetrones which are useful as aldose reductase inhibitors
SE9303274D0 (sv) * 1993-10-07 1993-10-07 Astra Ab Novel phenylethyl and phenylproplamines
HU226859B1 (en) 1997-10-27 2009-12-28 Neurosearch As Phenyl- or heteroaryl-homopiperazines, their use and medicaments containing them
US20040152710A1 (en) * 2002-10-15 2004-08-05 Deecher Darlene Coleman Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms
CA2595339C (en) * 2005-01-28 2014-08-19 Boehringer Ingelheim Pharma Gmbh & Co. Kg Method for producing isochromane and derivatives thereof
ES2462240T3 (es) 2006-02-28 2014-05-22 Dart Neuroscience (Cayman) Ltd Piperazinas terapéuticas como inhibidores de PDE4
US8927546B2 (en) 2006-02-28 2015-01-06 Dart Neuroscience (Cayman) Ltd. Therapeutic piperazines
WO2023288039A1 (en) * 2021-07-16 2023-01-19 Denali Therapeutics Inc. Compounds, compositions and methods

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1185934A (en) * 1967-06-28 1970-03-25 Pfizer & Co C Derivatives of 1,3(2H,4H)-Dioxoisoquinoline and preparation thereof
SE368009B (es) * 1971-09-16 1974-06-17 Kabi Ab
GB1424348A (en) * 1972-11-30 1976-02-11 Wyeth John & Brother Ltd Isoquinoline derivatives

Also Published As

Publication number Publication date
ATA651474A (de) 1975-10-15
BG26195A4 (es) 1979-02-15
FI52219B (es) 1977-03-31
FR2242979A1 (es) 1975-04-04
NO743220L (es) 1975-04-07
DK137124C (da) 1978-06-26
DK137124B (da) 1978-01-23
NO140978B (no) 1979-09-10
NL176363C (nl) 1985-04-01
MY8100330A (en) 1981-12-31
YU239174A (en) 1982-06-30
HU167869B (es) 1975-12-25
FR2242979B1 (es) 1978-02-03
NO140978C (no) 1979-12-19
BG22390A3 (es) 1977-02-20
JPS5050381A (es) 1975-05-06
RO63655A (fr) 1978-10-15
ES429473A1 (es) 1976-09-01
AT330777B (de) 1976-07-26
CA1025869A (en) 1978-02-07
SE424863B (sv) 1982-08-16
PL91712B1 (es) 1977-03-31
YU39928B (en) 1985-06-30
US3948898A (en) 1976-04-06
NL7411843A (nl) 1975-03-11
SE7411312L (es) 1975-03-10
HK4180A (en) 1980-02-08
DD115122A5 (es) 1975-09-12
PH12918A (en) 1979-10-10
GB1446791A (en) 1976-08-18
NL176363B (nl) 1984-11-01
SU545256A3 (ru) 1977-01-30
IE40742B1 (en) 1979-08-15
JPS596868B2 (ja) 1984-02-15
AU7302374A (en) 1976-03-11
FI246574A (es) 1975-03-09
CH605779A5 (es) 1978-10-13
CH605778A5 (es) 1978-10-13
ES433958A1 (es) 1976-11-16
DK472774A (es) 1975-05-05
ES433959A1 (es) 1976-11-16
IL45609A0 (en) 1974-11-29
IE40742L (en) 1975-03-08
FI52219C (fi) 1977-07-11
IL45609A (en) 1977-07-31
SU538664A3 (ru) 1976-12-05

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