ES425786A1 - Procedimiento para la preparacion de nuevas indolil-piperi-dino-(o 1,2,5,6-tetrahidro-piridil)-butirofenonas. - Google Patents
Procedimiento para la preparacion de nuevas indolil-piperi-dino-(o 1,2,5,6-tetrahidro-piridil)-butirofenonas.Info
- Publication number
- ES425786A1 ES425786A1 ES425786A ES425786A ES425786A1 ES 425786 A1 ES425786 A1 ES 425786A1 ES 425786 A ES425786 A ES 425786A ES 425786 A ES425786 A ES 425786A ES 425786 A1 ES425786 A1 ES 425786A1
- Authority
- ES
- Spain
- Prior art keywords
- salts
- methyl
- butyrophenones
- piperidino
- indolyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003839 salts Chemical class 0.000 title abstract 3
- -1 Indolyl-piperidino Chemical group 0.000 title abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000000460 chlorine Chemical group 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 229940125723 sedative agent Drugs 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
- 239000003204 tranquilizing agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2322470A DE2322470A1 (de) | 1973-05-04 | 1973-05-04 | Neue indolyl-piperidino-(bzw. 1,2,5,6tetrahydro-pyridyl-)butyrophenone und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES425786A1 true ES425786A1 (es) | 1976-06-16 |
Family
ID=5879989
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES425786A Expired ES425786A1 (es) | 1973-05-04 | 1974-04-29 | Procedimiento para la preparacion de nuevas indolil-piperi-dino-(o 1,2,5,6-tetrahidro-piridil)-butirofenonas. |
| ES430584A Expired ES430584A1 (es) | 1973-05-04 | 1974-10-02 | Procedimiento para la preparacion de nuevas indolil-pipe- ridino- (o 1,2,5,6-tetrahidro-piridil)-butirofenonas. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES430584A Expired ES430584A1 (es) | 1973-05-04 | 1974-10-02 | Procedimiento para la preparacion de nuevas indolil-pipe- ridino- (o 1,2,5,6-tetrahidro-piridil)-butirofenonas. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US3980658A (es) |
| JP (1) | JPS5025573A (es) |
| AT (1) | AT333281B (es) |
| AU (1) | AU6849874A (es) |
| BE (1) | BE814572A (es) |
| DE (1) | DE2322470A1 (es) |
| ES (2) | ES425786A1 (es) |
| FR (1) | FR2227873B1 (es) |
| GB (1) | GB1465826A (es) |
| IL (1) | IL44762A0 (es) |
| NL (1) | NL7405962A (es) |
| ZA (1) | ZA742816B (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2349331A1 (fr) * | 1976-04-30 | 1977-11-25 | Roussel Uclaf | Nouveaux derives de 2,3 dihydro a/4-(3-indolyl) 1-piperidinyl/methyl 1,4-benzodioxin-2-methanol, un procede pour leur preparation et leur application comme medicaments |
| FR2362628A1 (fr) * | 1976-08-26 | 1978-03-24 | Roussel Uclaf | Nouveaux derives du piperidyl-indole et leurs sels, procede de preparation et application a titre de medicaments |
| FR2421899A1 (fr) * | 1978-01-16 | 1979-11-02 | Roussel Uclaf | Nouveaux derives du tetrahydropyridinyl-indole et leurs sels, le procede de preparation et l'application a titre de medicaments de ces nouveaux produits |
| FR2444678A2 (fr) * | 1978-12-22 | 1980-07-18 | Roussel Uclaf | Nouveau procede de preparation de derives du piperidyl-indole et de leurs sels |
| FR2444679A2 (fr) * | 1978-12-22 | 1980-07-18 | Roussel Uclaf | Nouveaux derives du tetrahydropyridinyl-indole et leurs sels, procede de preparation et application comme medicaments |
| FR2458550A1 (fr) * | 1979-06-12 | 1981-01-02 | Roussel Uclaf | Nouveaux derives du tetrahydropyridinyl-indole, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant |
| FR2460946A2 (fr) * | 1979-07-06 | 1981-01-30 | Roussel Uclaf | Nouveaux derives du piperidyl-indole, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant |
| FR2477415A1 (fr) * | 1980-03-07 | 1981-09-11 | Roussel Uclaf | Application a titre de medicaments de derives du tetrahydropyridin-4-yl indole et compositions les renfermant |
| SE8004129L (sv) | 1979-07-13 | 1981-01-14 | Roussel Uclaf | Nya tetrahydropyridin-4-yl-indolderivat samt salter derav, framstellning och anvendning derav sasom lekemedel samt kompositioner innehallande dessa foreningar |
| FR2460947A1 (fr) | 1979-07-13 | 1981-01-30 | Roussel Uclaf | Nouveau derives n-substitues du tetrahydropyridinyl-indole, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant |
| FR2470128A2 (fr) * | 1979-11-23 | 1981-05-29 | Roussel Uclaf | Nouveaux derives du tetrahydropyridinyl-indole, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant |
| US4327103A (en) * | 1980-07-07 | 1982-04-27 | Hoechst-Roussel Pharmaceuticals Incorporated | 3-{3-[4-(4-Fluorobenzoyl)piperidyl]propyl}-2-methyl indole |
| US4359468A (en) * | 1981-02-25 | 1982-11-16 | Boehringer Ingelheim Ltd. | Antiallergic N-[4-(indolyl)-piperidino-alkyl]-benzimidazolones |
| FR2533924A1 (fr) * | 1982-10-05 | 1984-04-06 | Roussel Uclaf | Nouveaux derives du 4-(1h-indol-3-yl)a-methyl piperidine-1-ethanol, leurs sels, le procede de preparation, l'application a titre de medicaments et les compositions les renfermant |
| US4548939A (en) * | 1984-10-01 | 1985-10-22 | Janssen Pharmaceutica N. V. | 1H-Indol-3-yl containing 1,3-dimethyl-1H-purine-2,6-diones |
| IE58370B1 (en) * | 1985-04-10 | 1993-09-08 | Lundbeck & Co As H | Indole derivatives |
| US4742057A (en) * | 1985-12-05 | 1988-05-03 | Fujisawa Pharmaceutical Co., Ltd. | Antiallergic thiazole compounds |
| US5322851A (en) * | 1990-07-02 | 1994-06-21 | H. Lundbeck A/S | Indole derivatives |
| DK158590D0 (da) * | 1990-07-02 | 1990-07-02 | Lundbeck & Co As H | Indolderivater |
| US5643784A (en) * | 1990-12-04 | 1997-07-01 | H, Lundbeck A/S | Indan derivatives |
| NZ243065A (en) | 1991-06-13 | 1995-07-26 | Lundbeck & Co As H | Piperidine derivatives and pharmaceutical compositions |
| DK78692D0 (da) * | 1992-06-12 | 1992-06-12 | Lundbeck & Co As H | Dimere piperidin- og piperazinderivater |
| DK148292D0 (da) * | 1992-12-09 | 1992-12-09 | Lundbeck & Co As H | Forbindelser |
| GB9718712D0 (en) | 1997-09-03 | 1997-11-12 | Merck Sharp & Dohme | Theraputic Agents |
| ATE266024T1 (de) * | 2000-07-21 | 2004-05-15 | Lundbeck & Co As H | Indolderivate die zur behandlung von störungen des cns benutzt werden können |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3238215A (en) * | 1963-10-17 | 1966-03-01 | Sterling Drug Inc | 1-[(3-, 2-, and 1-indolyl)-lower-alkyl-, lower-alkenyl-, and lower-alkynyl]piperidines |
| BR6570394D0 (pt) * | 1964-07-02 | 1973-08-14 | Merck & Co Inc | Processo para a preparacao de compostos da serie indolica |
| GB1189064A (en) * | 1967-05-01 | 1970-04-22 | Sterling Drug Inc | Indole Derivatives |
| FR2193584B1 (es) * | 1972-07-28 | 1975-08-08 | Roussel Uclaf |
-
1973
- 1973-05-04 DE DE2322470A patent/DE2322470A1/de active Pending
-
1974
- 1974-04-23 AT AT334374A patent/AT333281B/de not_active IP Right Cessation
- 1974-04-29 ES ES425786A patent/ES425786A1/es not_active Expired
- 1974-05-02 JP JP49049613A patent/JPS5025573A/ja active Pending
- 1974-05-02 AU AU68498/74A patent/AU6849874A/en not_active Expired
- 1974-05-03 NL NL7405962A patent/NL7405962A/xx unknown
- 1974-05-03 GB GB1962374A patent/GB1465826A/en not_active Expired
- 1974-05-03 FR FR7415429A patent/FR2227873B1/fr not_active Expired
- 1974-05-03 ZA ZA00742816A patent/ZA742816B/xx unknown
- 1974-05-03 IL IL44762A patent/IL44762A0/xx unknown
- 1974-05-03 BE BE143944A patent/BE814572A/xx unknown
- 1974-05-06 US US05/467,497 patent/US3980658A/en not_active Expired - Lifetime
- 1974-10-02 ES ES430584A patent/ES430584A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BE814572A (fr) | 1974-11-04 |
| NL7405962A (es) | 1974-11-06 |
| ZA742816B (en) | 1975-06-25 |
| AU6849874A (en) | 1975-11-06 |
| FR2227873B1 (es) | 1977-09-09 |
| ATA334374A (de) | 1976-03-15 |
| JPS5025573A (es) | 1975-03-18 |
| IL44762A0 (en) | 1974-07-31 |
| AT333281B (de) | 1976-11-10 |
| FR2227873A1 (es) | 1974-11-29 |
| US3980658A (en) | 1976-09-14 |
| GB1465826A (en) | 1977-03-02 |
| DE2322470A1 (de) | 1974-11-21 |
| ES430584A1 (es) | 1976-09-01 |
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