JPS5951263A - 硝酸ピリジルアルキルエステル化合物、その製造法およびそれを含有する医薬製剤 - Google Patents

硝酸ピリジルアルキルエステル化合物、その製造法およびそれを含有する医薬製剤

Info

Publication number
JPS5951263A
JPS5951263A JP58132645A JP13264583A JPS5951263A JP S5951263 A JPS5951263 A JP S5951263A JP 58132645 A JP58132645 A JP 58132645A JP 13264583 A JP13264583 A JP 13264583A JP S5951263 A JPS5951263 A JP S5951263A
Authority
JP
Japan
Prior art keywords
alkyl
halogen
compound according
hydrogen
nitrooxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP58132645A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6350343B2 (US06291489-20010918-C00045.png
Inventor
Ikuo Ueda
育男 植田
Daizo Morino
森野 代三
Koichi Takimoto
浩一 瀧本
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of JPS5951263A publication Critical patent/JPS5951263A/ja
Publication of JPS6350343B2 publication Critical patent/JPS6350343B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61Halogen atoms or nitro radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
JP58132645A 1982-07-26 1983-07-19 硝酸ピリジルアルキルエステル化合物、その製造法およびそれを含有する医薬製剤 Granted JPS5951263A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8221592 1982-07-26
GB8221592 1982-07-26

Publications (2)

Publication Number Publication Date
JPS5951263A true JPS5951263A (ja) 1984-03-24
JPS6350343B2 JPS6350343B2 (US06291489-20010918-C00045.png) 1988-10-07

Family

ID=10531922

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58132645A Granted JPS5951263A (ja) 1982-07-26 1983-07-19 硝酸ピリジルアルキルエステル化合物、その製造法およびそれを含有する医薬製剤

Country Status (17)

Country Link
US (2) US4540701A (US06291489-20010918-C00045.png)
EP (1) EP0100081B1 (US06291489-20010918-C00045.png)
JP (1) JPS5951263A (US06291489-20010918-C00045.png)
KR (1) KR900005470B1 (US06291489-20010918-C00045.png)
AT (1) ATE40948T1 (US06291489-20010918-C00045.png)
AU (1) AU565791B2 (US06291489-20010918-C00045.png)
CA (1) CA1216850A (US06291489-20010918-C00045.png)
DE (1) DE3379255D1 (US06291489-20010918-C00045.png)
DK (1) DK311683A (US06291489-20010918-C00045.png)
ES (1) ES524375A0 (US06291489-20010918-C00045.png)
FI (1) FI832490L (US06291489-20010918-C00045.png)
GR (1) GR78629B (US06291489-20010918-C00045.png)
HU (1) HU190497B (US06291489-20010918-C00045.png)
NO (1) NO832700L (US06291489-20010918-C00045.png)
PH (1) PH18083A (US06291489-20010918-C00045.png)
SU (1) SU1189337A3 (US06291489-20010918-C00045.png)
ZA (1) ZA835048B (US06291489-20010918-C00045.png)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6081166A (ja) * 1983-10-11 1985-05-09 Fujisawa Pharmaceut Co Ltd 2−ニトロオキシメチル−6−クロロピリジンのβ−シクロデキストリン包接化合物およびその製造法
JPS6215A (ja) * 1985-02-26 1987-01-06 Fujisawa Pharmaceut Co Ltd 2−ニトロオキシメチル−6−クロロピリジンまたはそのβ−シクロデキストリン包接化合物含有持続性製剤
ZA885069B (en) * 1987-07-24 1989-03-29 Fujisawa Pharmaceutical Co Sustained-release percutaneous preparations
JPH02167279A (ja) * 1988-09-30 1990-06-27 Taisho Pharmaceut Co Ltd アポビンカミン酸誘導体
US5047543A (en) * 1988-11-24 1991-09-10 Taisho Pharmaceutical Co., Ltd. 1,4-dihydropyridine derivatives
CN106318877A (zh) * 2016-08-29 2017-01-11 刘翔 一种从茯砖茶中分离、纯化冠突散囊菌及其液态培养方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3275642A (en) * 1962-04-26 1966-09-27 Bard Pharmaceutical Inc 3-pyridine carbinol nitrate and its preparation
US3689494A (en) * 1971-03-31 1972-09-05 William R J Simpson N-pyridinealkyl-alkanolamine nitrates

Also Published As

Publication number Publication date
US4540701A (en) 1985-09-10
DE3379255D1 (en) 1989-04-06
AU1663583A (en) 1984-02-02
FI832490L (fi) 1984-01-27
KR840005426A (ko) 1984-11-12
US4613608A (en) 1986-09-23
SU1189337A3 (ru) 1985-10-30
DK311683D0 (da) 1983-07-05
GR78629B (US06291489-20010918-C00045.png) 1984-09-27
ZA835048B (en) 1984-03-28
HU190497B (en) 1986-09-29
NO832700L (no) 1984-02-06
ATE40948T1 (de) 1989-03-15
FI832490A0 (fi) 1983-07-07
CA1216850A (en) 1987-01-20
PH18083A (en) 1985-03-18
EP0100081A3 (en) 1985-05-02
ES8502088A1 (es) 1984-12-16
AU565791B2 (en) 1987-10-01
JPS6350343B2 (US06291489-20010918-C00045.png) 1988-10-07
EP0100081B1 (en) 1989-03-01
EP0100081A2 (en) 1984-02-08
KR900005470B1 (ko) 1990-07-30
ES524375A0 (es) 1984-12-16
DK311683A (da) 1984-01-27

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