JPS5921613A - 直腸投与製剤 - Google Patents
直腸投与製剤Info
- Publication number
- JPS5921613A JPS5921613A JP57132658A JP13265882A JPS5921613A JP S5921613 A JPS5921613 A JP S5921613A JP 57132658 A JP57132658 A JP 57132658A JP 13265882 A JP13265882 A JP 13265882A JP S5921613 A JPS5921613 A JP S5921613A
- Authority
- JP
- Japan
- Prior art keywords
- cyclodextrin
- drug
- administration
- pharmaceutical preparation
- added
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- LCJVIYPJPCBWKS-NXPQJCNCSA-N thymosin Chemical compound SC[C@@H](N)C(=O)N[C@H](CO)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CO)C(=O)N[C@H](CO)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@H]([C@H](C)O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@H](CCC(O)=O)C(O)=O LCJVIYPJPCBWKS-NXPQJCNCSA-N 0.000 description 1
- OHKOGUYZJXTSFX-KZFFXBSXSA-N ticarcillin Chemical compound C=1([C@@H](C(O)=O)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)C=CSC=1 OHKOGUYZJXTSFX-KZFFXBSXSA-N 0.000 description 1
- 229960004659 ticarcillin Drugs 0.000 description 1
- 238000002525 ultrasonication Methods 0.000 description 1
- 229960005356 urokinase Drugs 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
- C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/13—Luteinizing hormone-releasing hormone; related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nanotechnology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Medical Informatics (AREA)
- General Engineering & Computer Science (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57132658A JPS5921613A (ja) | 1982-07-28 | 1982-07-28 | 直腸投与製剤 |
| DE8383302118T DE3372705D1 (en) | 1982-04-30 | 1983-04-14 | Pharmaceutical composition and its use |
| EP83302118A EP0094157B1 (en) | 1982-04-30 | 1983-04-14 | Pharmaceutical composition and its use |
| CA000427019A CA1218605A (en) | 1982-07-28 | 1983-04-29 | Pharmaceutical composition and its rectal use |
| US06/753,816 US4670419A (en) | 1982-07-28 | 1985-07-08 | Pharmaceutical composition and its rectal use |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57132658A JPS5921613A (ja) | 1982-07-28 | 1982-07-28 | 直腸投与製剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5921613A true JPS5921613A (ja) | 1984-02-03 |
| JPH0524130B2 JPH0524130B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1993-04-06 |
Family
ID=15086465
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP57132658A Granted JPS5921613A (ja) | 1982-04-30 | 1982-07-28 | 直腸投与製剤 |
Country Status (3)
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59190916A (ja) * | 1983-04-14 | 1984-10-29 | Morishita Jintan Kk | 親水性物質含有軟カプセル |
| JPH0618777B2 (ja) * | 1988-05-27 | 1994-03-16 | アメリカ合衆国 | 精神神経性欠損症の治療に用いられる組成物 |
| US7402559B2 (en) | 1999-03-24 | 2008-07-22 | Msh Pharma, Incorporated | Composition and method of treatment for urogenital conditions |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8514090D0 (en) * | 1985-06-04 | 1985-07-10 | Sandoz Ltd | Organic compounds |
| US4652443A (en) * | 1983-06-07 | 1987-03-24 | Japan Atomic Energy Research Institute | Slow-release composite and process for producing the same |
| US5411951A (en) * | 1984-10-04 | 1995-05-02 | Monsanto Company | Prolonged release of biologically active somatotropin |
| US5474980A (en) * | 1984-10-04 | 1995-12-12 | Monsanto Company | Prolonged release of biologically active somatotropins |
| US4870060A (en) * | 1985-03-15 | 1989-09-26 | Janssen Pharmaceutica | Derivatives of γ-cylodextrin |
| CA1275922C (en) * | 1985-11-28 | 1990-11-06 | Harunobu Amagase | Treatment of cancer |
| US5389366A (en) * | 1986-09-19 | 1995-02-14 | Yamanouchi Pharmaceutical Co., Ltd. | Neocarzinostatin derivative composition for oral administration |
| CA1296253C (en) * | 1986-10-20 | 1992-02-25 | Praveen Tyle | Stabilized growth hormone compositions |
| US5162306A (en) * | 1987-01-23 | 1992-11-10 | Donaldson Lloyd E | Composition and method for producing superovulation in mammals |
| US4877774A (en) * | 1987-09-09 | 1989-10-31 | The United States Of America As Represented By The Department Of Health And Human Services | Administration of steroid hormones |
| PT88490B (pt) * | 1987-09-14 | 1992-11-30 | Novo Nordisk As | Processo para a preparacao de composicoes farmaceuticas para libertacao nao-enterica trans-mucosa contendo monossacaridos ou oligossacaridos |
| ES2033086T3 (es) * | 1988-01-29 | 1993-03-01 | Sankyo Company Limited | Un procedimiento para la preparacion de una composicion farmaceutica. |
| NO179479C (no) * | 1988-03-11 | 1996-10-16 | Teikoku Seiyaku Kk | Fremgangsmåte for fremstilling av et intravaginalt farmasöytisk preparat |
| JP2911496B2 (ja) * | 1989-09-11 | 1999-06-23 | 帝國製薬株式会社 | 生理活性ポリペプチド含有高吸収性経膣剤 |
| IT1243379B (it) * | 1990-07-27 | 1994-06-10 | Giuliani Spa | Composizione farmaceutica adatta alla somministrazione rettale di principi attivi che esplicano un'azione di medicazione a livello del colon prevalentemente di tipo topico |
| NZ244796A (en) * | 1992-08-18 | 1995-05-26 | Scherer Corp R P | Capsule shell of soft gelatin contains a medicament and has a removable tab |
| JPH0776527A (ja) * | 1993-06-28 | 1995-03-20 | Hayashibara Biochem Lab Inc | 半固形製剤とその製造方法 |
| US5668097A (en) * | 1994-08-12 | 1997-09-16 | The Procter & Gamble Company | Uncomplexed cyclodextrin solutions for odor control on inanimate surfaces |
| EP0800828A4 (en) * | 1994-12-28 | 1999-03-31 | Teikoku Hormone Mfg Co Ltd | TRANSMUCOSAL PREPARATION |
| US6071539A (en) * | 1996-09-20 | 2000-06-06 | Ethypharm, Sa | Effervescent granules and methods for their preparation |
| US5916883A (en) * | 1996-11-01 | 1999-06-29 | Poly-Med, Inc. | Acylated cyclodextrin derivatives |
| US5985248A (en) * | 1996-12-31 | 1999-11-16 | Inhale Therapeutic Systems | Processes for spray drying solutions of hydrophobic drugs and compositions thereof |
| US20030203036A1 (en) * | 2000-03-17 | 2003-10-30 | Gordon Marc S. | Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients |
| EP0983769A4 (en) | 1997-04-14 | 2002-05-02 | Mitsubishi Tokyo Pharm Inc | PERMUCOSE FORMULATION |
| US8765177B2 (en) * | 1997-09-12 | 2014-07-01 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
| US7153845B2 (en) * | 1998-08-25 | 2006-12-26 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
| US20030166525A1 (en) * | 1998-07-23 | 2003-09-04 | Hoffmann James Arthur | FSH Formulation |
| EP1174152B1 (en) * | 2000-03-30 | 2006-12-20 | Council of Scientific and Industrial Research | Inclusion complex of an opioid peptide with cyclodextrin |
| EP1280559B1 (en) * | 2000-05-11 | 2006-03-08 | Eastman Chemical Company | Acylated cyclodextrin guest inclusion complexes |
| CA2423532A1 (en) * | 2000-08-17 | 2002-02-21 | Sin Hang Lee | Device for reduction of the anal cushions in the treatment of minor hemorrhoidal disease |
| US6364852B1 (en) * | 2000-08-17 | 2002-04-02 | Sin Hang Lee | Device for reduction of the anal cushions in the treatment of minor hemorrhoidal disease |
| AU2001288102A1 (en) * | 2000-09-22 | 2002-04-02 | Takeda Chemical Industries Ltd. | Solid preparations |
| GB0208742D0 (en) | 2002-04-17 | 2002-05-29 | Bradford Particle Design Ltd | Particulate materials |
| US7582284B2 (en) * | 2002-04-17 | 2009-09-01 | Nektar Therapeutics | Particulate materials |
| US6979672B2 (en) * | 2002-12-20 | 2005-12-27 | Polichem, S.A. | Cyclosporin-based pharmaceutical compositions |
| DK2216407T3 (en) | 2003-03-07 | 2016-03-29 | Alnylam Pharmaceuticals Inc | therapeutic compositions |
| US7812120B2 (en) * | 2003-03-21 | 2010-10-12 | Par Pharmaceutical, Inc. | Nasal calcitonin formulations containing chlorobutanol |
| ATE492292T2 (de) * | 2003-04-02 | 2011-01-15 | Ares Trading Sa | Flüssige oder gefriergetrocknete pharmazeutische zusammensetzung enthaltend fsh und/oder lh, das nichtionische tensid poloxamer 188 und ein antibakterielles mittel |
| EP2660322A3 (en) | 2003-04-17 | 2013-11-13 | Alnylam Pharmaceuticals Inc. | Modified iRNA agents |
| PL1638595T3 (pl) * | 2003-06-20 | 2013-06-28 | Ares Trading Sa | Liofilizowane formulacje FSH/LH |
| AU2003903597A0 (en) * | 2003-07-11 | 2003-07-24 | Jakov Vaisman | Treatment of premature ejaculation |
| EP1663159A4 (en) * | 2003-09-10 | 2010-06-09 | Map Pharmaceuticals Inc | AEROSOL FORMULATIONS FOR THE DELIVERY OF DIHYDROERGOTAMINE TO THE SYSTEMIC CIRCULATION BY PULMONARY INHALATION |
| US8123760B2 (en) * | 2005-08-05 | 2012-02-28 | Plexus Biomedical, Inc. | Method, apparatus and system for preventing or reducing the severity of hemorrhoids |
| FR2898817B1 (fr) * | 2006-03-23 | 2008-08-08 | Univ Rouen | Association de substance oleagineuse avec un melange d'au moins deux cyclodextrines |
| CA2651177C (en) * | 2006-05-03 | 2016-11-22 | Plexus Biomedical, Inc. | Apparatus and method of inhibiting perianal tissue damage |
| ES2538082T3 (es) | 2007-02-11 | 2015-06-17 | Map Pharmaceuticals Inc | Método de administración terapéutica de DHE para permitir el rápido alivio de migraña mientras que se minimiza el perfil de efectos secundarios |
| WO2009073809A2 (en) | 2007-12-04 | 2009-06-11 | Alnylam Pharmaceuticals, Inc. | Carbohydrate conjugates as delivery agents for oligonucleotides |
| CA3044980A1 (en) | 2008-04-11 | 2009-10-15 | Alnylam Pharmaceuticals, Inc. | Site-specific delivery of nucleic acids by combining targeting ligands with endosomolytic components |
| WO2011109427A2 (en) | 2010-03-01 | 2011-09-09 | Alnylam Pharmaceuticals, Inc. | Improving the biological activity of sirna through modulation of its thermodynamic profile |
| FR2989001B1 (fr) * | 2012-04-06 | 2017-07-21 | Centre Nat Rech Scient | Microparticules et nanoparticules constituees de polysaccharides hydrophobises et d'une alpha-cyclodextrine |
| US8597306B1 (en) | 2013-03-14 | 2013-12-03 | Plexus Biomedical, Inc. | Labor management methods for decreasing the incidence of cesarean childbirth |
| FR3006315B1 (fr) * | 2013-05-31 | 2015-10-02 | Centre Nat Rech Scient | Microparticules et nanoparticules auto-associatives composees de proteines |
| US20170304459A1 (en) | 2014-10-10 | 2017-10-26 | Alnylam Pharmaceuticals, Inc. | Methods and compositions for inhalation delivery of conjugated oligonucleotide |
| US10080520B2 (en) | 2015-02-27 | 2018-09-25 | Stetrix, Inc. | Labor monitoring of pelvic floor |
| WO2017048566A1 (en) * | 2015-09-15 | 2017-03-23 | C.B. Fleet Company, Incorporated | Bisacodyl compositions and delivery apparatus |
| US11376220B2 (en) | 2017-06-30 | 2022-07-05 | Therio, LLC | Single-injection methods and formulations to induce and control multiple ovarian follicles in bovine, caprine, ovine, camelid and other female animals |
| US12329669B2 (en) | 2021-10-27 | 2025-06-17 | Stetrix, Inc. | Perianal support device with flexible side supports |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5592312A (en) * | 1978-12-29 | 1980-07-12 | Yamanouchi Pharmaceut Co Ltd | Suppository containing bronchodilating compound |
| JPS55143912A (en) * | 1980-01-28 | 1980-11-10 | Sumitomo Chem Co Ltd | Useful preparation comprising bencyclane fumarate |
| JPS5633371A (en) * | 1979-08-21 | 1981-04-03 | Mitsubishi Electric Corp | Controller for elevator when earthquake |
| JPS5634618A (en) * | 1979-08-30 | 1981-04-06 | Ota Seiyaku Kk | Production of flurbiprofen preparation |
| GB2090738A (en) * | 1980-12-19 | 1982-07-21 | Chinoin Gyogyszer Es Vegyeszet | Suppository containing active ingredient - cyclodextrin complex |
-
1982
- 1982-07-28 JP JP57132658A patent/JPS5921613A/ja active Granted
-
1983
- 1983-04-29 CA CA000427019A patent/CA1218605A/en not_active Expired
-
1985
- 1985-07-08 US US06/753,816 patent/US4670419A/en not_active Expired - Lifetime
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5592312A (en) * | 1978-12-29 | 1980-07-12 | Yamanouchi Pharmaceut Co Ltd | Suppository containing bronchodilating compound |
| JPS5633371A (en) * | 1979-08-21 | 1981-04-03 | Mitsubishi Electric Corp | Controller for elevator when earthquake |
| JPS5634618A (en) * | 1979-08-30 | 1981-04-06 | Ota Seiyaku Kk | Production of flurbiprofen preparation |
| JPS55143912A (en) * | 1980-01-28 | 1980-11-10 | Sumitomo Chem Co Ltd | Useful preparation comprising bencyclane fumarate |
| GB2090738A (en) * | 1980-12-19 | 1982-07-21 | Chinoin Gyogyszer Es Vegyeszet | Suppository containing active ingredient - cyclodextrin complex |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59190916A (ja) * | 1983-04-14 | 1984-10-29 | Morishita Jintan Kk | 親水性物質含有軟カプセル |
| JPH0618777B2 (ja) * | 1988-05-27 | 1994-03-16 | アメリカ合衆国 | 精神神経性欠損症の治療に用いられる組成物 |
| US7402559B2 (en) | 1999-03-24 | 2008-07-22 | Msh Pharma, Incorporated | Composition and method of treatment for urogenital conditions |
Also Published As
| Publication number | Publication date |
|---|---|
| US4670419A (en) | 1987-06-02 |
| CA1218605A (en) | 1987-03-03 |
| JPH0524130B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1993-04-06 |
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