JPS59174742A - 微小粒子を区分又は選別する方法及びその装置 - Google Patents

微小粒子を区分又は選別する方法及びその装置

Info

Publication number
JPS59174742A
JPS59174742A JP58048674A JP4867483A JPS59174742A JP S59174742 A JPS59174742 A JP S59174742A JP 58048674 A JP58048674 A JP 58048674A JP 4867483 A JP4867483 A JP 4867483A JP S59174742 A JPS59174742 A JP S59174742A
Authority
JP
Japan
Prior art keywords
light
cell
time
signal
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP58048674A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0145018B2 (enExample
Inventor
Mikio Yamashita
幹雄 山下
Takuzo Sato
佐藤　卓蔵
Yoshio Noguchi
野口　義夫
Yoshinobu Uchibori
内堀　義信
Akio Shinohara
篠原　彰男
Hiroshi Soga
博 曽我
Sadayuki Miyazaki
宮崎　貞行
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Institute of Advanced Industrial Science and Technology
Resonac Holdings Corp
Original Assignee
Agency of Industrial Science and Technology
Showa Denko KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency of Industrial Science and Technology, Showa Denko KK filed Critical Agency of Industrial Science and Technology
Priority to JP58048674A priority Critical patent/JPS59174742A/ja
Publication of JPS59174742A publication Critical patent/JPS59174742A/ja
Priority to US06/859,203 priority patent/US4778593A/en
Publication of JPH0145018B2 publication Critical patent/JPH0145018B2/ja
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
    • B07C—POSTAL SORTING; SORTING INDIVIDUAL ARTICLES, OR BULK MATERIAL FIT TO BE SORTED PIECE-MEAL, e.g. BY PICKING
    • B07C5/00—Sorting according to a characteristic or feature of the articles or material being sorted, e.g. by control effected by devices which detect or measure such characteristic or feature; Sorting by manually actuated devices, e.g. switches
    • B07C5/34—Sorting according to other particular properties
    • B07C5/342—Sorting according to other particular properties according to optical properties, e.g. colour
    • B07C5/3425—Sorting according to other particular properties according to optical properties, e.g. colour of granular material, e.g. ore particles, grain
    • B07C5/3427—Sorting according to other particular properties according to optical properties, e.g. colour of granular material, e.g. ore particles, grain by changing or intensifying the optical properties prior to scanning, e.g. by inducing fluorescence under UV or x-radiation, subjecting the material to a chemical reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties

Landscapes

  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP58048674A 1983-03-25 1983-03-25 微小粒子を区分又は選別する方法及びその装置 Granted JPS59174742A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP58048674A JPS59174742A (ja) 1983-03-25 1983-03-25 微小粒子を区分又は選別する方法及びその装置
US06/859,203 US4778593A (en) 1983-03-25 1986-04-28 Method and apparatus for discriminating minute particles

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58048674A JPS59174742A (ja) 1983-03-25 1983-03-25 微小粒子を区分又は選別する方法及びその装置

Publications (2)

Publication Number Publication Date
JPS59174742A true JPS59174742A (ja) 1984-10-03
JPH0145018B2 JPH0145018B2 (enExample) 1989-10-02

Family

ID=12809866

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58048674A Granted JPS59174742A (ja) 1983-03-25 1983-03-25 微小粒子を区分又は選別する方法及びその装置

Country Status (2)

Country Link
US (1) US4778593A (enExample)
JP (1) JPS59174742A (enExample)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6394156A (ja) * 1986-10-07 1988-04-25 Toa Medical Electronics Co Ltd 流体中の細胞分析装置
JPH03221837A (ja) * 1990-01-26 1991-09-30 Canon Inc 検体測定方法及び検体測定装置
JP2006275858A (ja) * 2005-03-30 2006-10-12 National Institute Of Advanced Industrial & Technology 蛍光検出方法、蛍光検出用ビーズの作製方法及び蛍光検出用ビーズ
JP2006284231A (ja) * 2005-03-31 2006-10-19 National Institute Of Advanced Industrial & Technology 遺伝子断片中のヌクレオチドの種類の特定方法
KR100938926B1 (ko) 2008-03-05 2010-01-27 재단법인서울대학교산학협력재단 초음파 빔에 의한 세포식별을 이용한 세포 분류장치
JP2012251881A (ja) * 2011-06-03 2012-12-20 Bay Bioscience Kk 液体フローに含まれる生物学的粒子を分析するシステム

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US5041733A (en) * 1987-03-20 1991-08-20 Agency Of Industrial Science & Technology Method and apparatus for identifying chromosomes or cells
US4987539A (en) * 1987-08-05 1991-01-22 Stanford University Apparatus and method for multidimensional characterization of objects in real time
US4896048A (en) * 1988-05-27 1990-01-23 High Yield Technology Scattering-type particle detection device for use in high temperature process chambers
US4981580A (en) * 1989-05-01 1991-01-01 Coulter Corporation Coincidence arbitration in a flow cytomery sorting system
US4979824A (en) * 1989-05-26 1990-12-25 Board Of Trustees Of The Leland Stanford Junior University High sensitivity fluorescent single particle and single molecule detection apparatus and method
NO894680L (no) * 1989-11-24 1991-05-27 Flowtech A S V Harald Steen Pulsmodulasjon av eksitasjonslyskilden i vaeskestroemcytofotometere.
US5101978A (en) * 1989-11-27 1992-04-07 The United States Of America As Represented By The Secretary Of The Army Fluidic sorting device for two or more materials suspended in a fluid
US5204884A (en) * 1991-03-18 1993-04-20 University Of Rochester System for high-speed measurement and sorting of particles
DE69132273D1 (de) * 1990-10-10 2000-08-03 Univ Maryland Verfahren und vorrichtung zur bestimmung von lebensdauer von fluoreszenz in der durchflusscytometrie
US5199576A (en) * 1991-04-05 1993-04-06 University Of Rochester System for flexibly sorting particles
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EP0515211A3 (en) * 1991-05-23 1993-04-07 Becton Dickinson And Company Apparatus and method for phase resolved fluorescence lifetimes of independent and varying amplitude pulses
JPH0526810A (ja) * 1991-07-23 1993-02-02 Hamamatsu Photonics Kk 微粒子の螢光検出装置
US5281825A (en) * 1991-09-05 1994-01-25 The University Of Maryland School Of Medicine Phase fluorometry using a modulated electroluminescent lamp as a light source
JPH0610900A (ja) * 1992-04-27 1994-01-21 Canon Inc 液体移動方法及び移動装置ならびにこれを利用した測定装置
US5315122A (en) * 1992-08-25 1994-05-24 Becton, Dickinson And Company Apparatus and method for fluorescent lifetime measurement
US5367474A (en) * 1993-02-08 1994-11-22 Coulter Corporation Flow cytometer
US5419438A (en) * 1993-11-24 1995-05-30 Simco/Ramic Corporation Apparatus and method for sorting post-consumer articles according to PVC content
US5733739A (en) * 1995-06-07 1998-03-31 Inphocyte, Inc. System and method for diagnosis of disease by infrared analysis of human tissues and cells
ATE496288T1 (de) 1995-10-11 2011-02-15 Luminex Corp Gleichzeitige mehrfachanalyse klinischer proben
US5736330A (en) * 1995-10-11 1998-04-07 Luminex Corporation Method and compositions for flow cytometric determination of DNA sequences
US5981180A (en) * 1995-10-11 1999-11-09 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and methods
US5837547A (en) * 1995-12-27 1998-11-17 Caribbean Microparticles Corporation Flow cytometer calibration method
US6025201A (en) * 1995-12-28 2000-02-15 Bayer Corporation Highly sensitive, accurate, and precise automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples
US5817519A (en) * 1995-12-28 1998-10-06 Bayer Corporation Automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples
US5848977A (en) * 1996-02-16 1998-12-15 Inphocyte, Inc. Sample holder for cells
US6449562B1 (en) 1996-10-10 2002-09-10 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and method
DE69830598T2 (de) 1997-01-31 2006-05-18 The Horticulture And Food Research Institute Of New Zealand Limited Optische vorrichtung und methode
US6071689A (en) 1997-12-31 2000-06-06 Xy, Inc. System for improving yield of sexed embryos in mammals
US6149867A (en) 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
US6281018B1 (en) 1998-02-26 2001-08-28 Coulter International Corp. Selective purification and enrichment sorting of flow cytometer droplets based upon analysis of droplet precursor regions
US6323495B1 (en) 1999-09-24 2001-11-27 Umm Electronics, Inc. Method and apparatus for the determination of phase delay in a lifetime fluorometer without the use of lifetime standards
US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
AU2002237689B2 (en) 2000-11-29 2008-01-10 Xy, Llc. System to separate frozen-thawed spermatozoa into X-chromosome bearing and Y-chromosome bearing populations
JP4219549B2 (ja) * 2000-12-20 2009-02-04 富士フイルム株式会社 放射線画像読取方法および装置
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
CA2532376C (en) 2002-08-01 2015-05-12 Colorado State University Research Foundation Low pressure sperm cell separation system
BRPI0313476B1 (pt) 2002-08-15 2015-06-23 Xy Llc Citômetro de fluxo de alta resolução
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
DK2308419T3 (da) 2003-03-28 2016-06-06 Inguran Llc Fremgangsmåde til bedømmelse af farvningstilstandene for dyresperm, som skal sorteres.
NZ544103A (en) 2003-05-15 2010-10-29 Xy Llc Efficient haploid cell sorting for flow cytometer systems
US7446296B2 (en) * 2004-01-30 2008-11-04 Hamamatsu Photonics K.K. Streak device
JP2007531523A (ja) 2004-03-29 2007-11-08 モンサント テクノロジー エルエルシー Ｘまたはｙ染色体担持豊富化集団に仕分けるための精子懸濁液
CA2574499C (en) 2004-07-22 2016-11-29 Monsanto Technology Llc Process for enriching a population of sperm cells
US7440099B2 (en) * 2006-08-14 2008-10-21 Icf Technology Limited Droplets detecting system
CN101148119B (zh) * 2006-09-20 2010-08-25 鸿富锦精密工业（深圳）有限公司 墨滴检测系统
US20090126470A1 (en) * 2007-11-15 2009-05-21 Kabushiki Kaisha Toshiba Specimen inspecting apparatus and stirring apparatus
EP2157599A1 (en) * 2008-08-21 2010-02-24 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO Method and apparatus for identification of biological material
DE102011054659A1 (de) * 2011-10-20 2013-04-25 AeroMegt GmbH Verfahren und Vorrichtung zum Messen von Aerosolen in einem großen Volumenstrom
US8994945B2 (en) 2011-10-27 2015-03-31 Fluid Imaging Technologies, Inc. Method of treatment analysis with particle imaging
JP6065527B2 (ja) * 2012-11-08 2017-01-25 ソニー株式会社 微小粒子分取装置及び微小粒子分取方法
US9983115B2 (en) 2015-09-21 2018-05-29 Fluid Imaging Technologies, Inc. System and method for monitoring particles in a fluid using ratiometric cytometry
US20170336431A1 (en) * 2016-05-19 2017-11-23 Purdue Research Foundation System and method for measuring exhaust flow velocity of supersonic nozzles
US10605716B2 (en) * 2017-07-21 2020-03-31 Ricoh Company, Ltd. Particle counting apparatus, particle counting method, and particle containing sample
DE102018210015B4 (de) * 2018-06-20 2020-04-02 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Vorrichtung und Verfahren zur Sortierung von pulverförmigem, partikelförmigem, granulatförmigem oder stückförmigem Material

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JPS4874292A (enExample) * 1971-12-23 1973-10-06
JPS5190868A (enExample) * 1975-02-06 1976-08-09

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6394156A (ja) * 1986-10-07 1988-04-25 Toa Medical Electronics Co Ltd 流体中の細胞分析装置
JPH03221837A (ja) * 1990-01-26 1991-09-30 Canon Inc 検体測定方法及び検体測定装置
JP2006275858A (ja) * 2005-03-30 2006-10-12 National Institute Of Advanced Industrial & Technology 蛍光検出方法、蛍光検出用ビーズの作製方法及び蛍光検出用ビーズ
JP2006284231A (ja) * 2005-03-31 2006-10-19 National Institute Of Advanced Industrial & Technology 遺伝子断片中のヌクレオチドの種類の特定方法
KR100938926B1 (ko) 2008-03-05 2010-01-27 재단법인서울대학교산학협력재단 초음파 빔에 의한 세포식별을 이용한 세포 분류장치
JP2012251881A (ja) * 2011-06-03 2012-12-20 Bay Bioscience Kk 液体フローに含まれる生物学的粒子を分析するシステム

Also Published As

Publication number Publication date
US4778593A (en) 1988-10-18
JPH0145018B2 (enExample) 1989-10-02

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