JPS59108748A - 置換テトラヒドロナフタレン化合物 - Google Patents

置換テトラヒドロナフタレン化合物

Info

Publication number
JPS59108748A
JPS59108748A JP58215891A JP21589183A JPS59108748A JP S59108748 A JPS59108748 A JP S59108748A JP 58215891 A JP58215891 A JP 58215891A JP 21589183 A JP21589183 A JP 21589183A JP S59108748 A JPS59108748 A JP S59108748A
Authority
JP
Japan
Prior art keywords
formula
compound
carbamoyl
tetrahydronaphthalene
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP58215891A
Other languages
English (en)
Japanese (ja)
Inventor
ニコラス・ジエイムズ・バツハ
エドムンド・カ−ル・コ−ンフエルド
ロバ−ト・ダニエル・タイタス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of JPS59108748A publication Critical patent/JPS59108748A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
    • B01J23/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
    • B01J23/44—Palladium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/22—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/48—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring being part of a condensed ring system of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
    • C07C243/38—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Materials Engineering (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
JP58215891A 1982-11-16 1983-11-15 置換テトラヒドロナフタレン化合物 Pending JPS59108748A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US442074 1982-11-16
US06/442,074 US4448990A (en) 1982-11-16 1982-11-16 Hydroxyaminotetralincarboxamides

Publications (1)

Publication Number Publication Date
JPS59108748A true JPS59108748A (ja) 1984-06-23

Family

ID=23755442

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58215891A Pending JPS59108748A (ja) 1982-11-16 1983-11-15 置換テトラヒドロナフタレン化合物

Country Status (11)

Country Link
US (1) US4448990A (enEXAMPLES)
EP (1) EP0109815B1 (enEXAMPLES)
JP (1) JPS59108748A (enEXAMPLES)
KR (1) KR870000204B1 (enEXAMPLES)
CA (1) CA1198122A (enEXAMPLES)
DE (1) DE3363813D1 (enEXAMPLES)
DK (1) DK515483D0 (enEXAMPLES)
GB (1) GB2130209B (enEXAMPLES)
GR (1) GR79034B (enEXAMPLES)
HU (1) HU196168B (enEXAMPLES)
IL (1) IL70158A (enEXAMPLES)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5970653A (ja) * 1982-10-15 1984-04-21 Takeda Chem Ind Ltd 眼圧低下剤
CA2012502A1 (en) * 1989-03-21 1990-09-21 Novartis Ag Initiators for materials which can be polymerized cationically
DE3924365A1 (de) * 1989-07-22 1991-01-24 Boehringer Ingelheim Kg 2-amino-7-carbamoyl-1,2,3,4- tetrahydronaphthaline, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
EP0697894A4 (en) * 1993-03-31 1996-05-01 Univ Pennsylvania DOPAMINE D-3 AND SEROTONIN (5-HT 1A) RECEPTOR LIGANDS AND IMAGING AGENTS
US5763609A (en) * 1996-03-21 1998-06-09 Neurogen Corporation Certain pyrrolo pyridine-3-carboxamides; a new class of gaba brain receptor ligands
CN1159292C (zh) * 1996-05-31 2004-07-28 法玛西雅厄普约翰美国公司 用作选择性多巴胺d3配体的芳基取代的环胺类化合物
IT1294931B1 (it) * 1997-09-22 1999-04-23 Sigma Tau Ind Farmaceuti Derivati della 2-amminotetralina procedimento per la loro preparazione e composizioni farmaceutiche che li contengono, attive nella
RU2442781C2 (ru) * 2004-10-14 2012-02-20 Абботт ГмбХ унд Ко. КГ Арилсульфонилметильные или арилсульфонамидные производные ароматических соединений, фармацевтическая композиция на их основе и способ лечения расстройств, восприимчивых к лечению лигандами дофаминовых d3 рецепторов, с их помощью

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2029509A (en) * 1932-12-23 1936-02-04 Ici Ltd Arylamides of 2,3-hydroxynaphthoic acids
US4163063A (en) * 1976-01-02 1979-07-31 University Of Iowa Research Foundation Aminotetralin adrenergic β-agonists
DE2752659A1 (de) * 1976-12-07 1978-06-08 Sandoz Ag Neue tetralinderivate, ihre herstellung und verwendung
SE8004002L (sv) * 1980-05-29 1981-11-30 Arvidsson Folke Lars Erik Terapeutiskt anvendbara tetralinderivat

Also Published As

Publication number Publication date
IL70158A0 (en) 1984-02-29
GB2130209B (en) 1986-05-29
GB8330279D0 (en) 1983-12-21
HU196168B (en) 1988-10-28
GR79034B (enEXAMPLES) 1984-10-02
DE3363813D1 (en) 1986-07-03
EP0109815B1 (en) 1986-05-28
KR870000204B1 (ko) 1987-02-16
GB2130209A (en) 1984-05-31
DK515483D0 (da) 1983-11-11
CA1198122A (en) 1985-12-17
EP0109815A1 (en) 1984-05-30
KR840007561A (ko) 1984-12-08
US4448990A (en) 1984-05-15
IL70158A (en) 1987-03-31

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