JPS5857399A - ニンジンサポニン、その分離法及び製造法並びに用途 - Google Patents
ニンジンサポニン、その分離法及び製造法並びに用途Info
- Publication number
- JPS5857399A JPS5857399A JP15699381A JP15699381A JPS5857399A JP S5857399 A JPS5857399 A JP S5857399A JP 15699381 A JP15699381 A JP 15699381A JP 15699381 A JP15699381 A JP 15699381A JP S5857399 A JPS5857399 A JP S5857399A
- Authority
- JP
- Japan
- Prior art keywords
- lower alcohol
- water
- concentrate
- solution
- butanol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 title description 8
- 238000000926 separation method Methods 0.000 title description 3
- 241000208340 Araliaceae Species 0.000 title 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 86
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims abstract description 68
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 46
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- 239000000284 extract Substances 0.000 claims abstract description 23
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- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 16
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- CKUVNOCSBYYHIS-IRFFNABBSA-N (20S)-ginsenoside Rh2 Chemical compound O([C@H]1CC[C@]2(C)[C@H]3C[C@@H](O)[C@H]4[C@@]([C@@]3(CC[C@H]2C1(C)C)C)(C)CC[C@@H]4[C@@](C)(O)CCC=C(C)C)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O CKUVNOCSBYYHIS-IRFFNABBSA-N 0.000 description 6
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- WORJEOGGNQDSOE-UHFFFAOYSA-N chloroform;methanol Chemical compound OC.ClC(Cl)Cl WORJEOGGNQDSOE-UHFFFAOYSA-N 0.000 description 6
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- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 3
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- 235000019271 petrolatum Nutrition 0.000 description 1
- 229940066842 petrolatum Drugs 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- GRLPQNLYRHEGIJ-UHFFFAOYSA-J potassium aluminium sulfate Chemical compound [Al+3].[K+].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O GRLPQNLYRHEGIJ-UHFFFAOYSA-J 0.000 description 1
- 229940088417 precipitated calcium carbonate Drugs 0.000 description 1
- 230000002062 proliferating effect Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 235000013772 propylene glycol Nutrition 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- 206010038038 rectal cancer Diseases 0.000 description 1
- 201000001275 rectum cancer Diseases 0.000 description 1
- 230000001850 reproductive effect Effects 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 235000020374 simple syrup Nutrition 0.000 description 1
- 201000000849 skin cancer Diseases 0.000 description 1
- 201000004477 skin sarcoma Diseases 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 235000015096 spirit Nutrition 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000010025 steaming Methods 0.000 description 1
- 229960005322 streptomycin Drugs 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 239000003760 tallow Substances 0.000 description 1
- 238000004809 thin layer chromatography Methods 0.000 description 1
- 208000008732 thymoma Diseases 0.000 description 1
- 208000013076 thyroid tumor Diseases 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 206010046766 uterine cancer Diseases 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 239000011787 zinc oxide Substances 0.000 description 1
- 235000014692 zinc oxide Nutrition 0.000 description 1
- XOOUIPVCVHRTMJ-UHFFFAOYSA-L zinc stearate Chemical compound [Zn+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O XOOUIPVCVHRTMJ-UHFFFAOYSA-L 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15699381A JPS5857399A (ja) | 1981-10-01 | 1981-10-01 | ニンジンサポニン、その分離法及び製造法並びに用途 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15699381A JPS5857399A (ja) | 1981-10-01 | 1981-10-01 | ニンジンサポニン、その分離法及び製造法並びに用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5857399A true JPS5857399A (ja) | 1983-04-05 |
| JPH0128759B2 JPH0128759B2 (enrdf_load_stackoverflow) | 1989-06-05 |
Family
ID=15639825
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP15699381A Granted JPS5857399A (ja) | 1981-10-01 | 1981-10-01 | ニンジンサポニン、その分離法及び製造法並びに用途 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5857399A (enrdf_load_stackoverflow) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5859921A (ja) * | 1981-10-02 | 1983-04-09 | Rooto Seiyaku Kk | アマチヤヅルサポニンを含有する抗癌剤 |
| WO1997031013A1 (en) * | 1996-02-22 | 1997-08-28 | Il Hwa Co., Ltd. | Metabolites of ginseng saponins by human intestinal bacteria and its preparation for an anticancer |
| WO2011002033A1 (ja) | 2009-06-30 | 2011-01-06 | ライオン株式会社 | 糖代謝改善剤及び糖代謝改善組成物 |
| WO2011074377A1 (ja) | 2009-12-14 | 2011-06-23 | ライオン株式会社 | プロトパナキサトリオール及びプロトパナキサジオール含有組成物 |
-
1981
- 1981-10-01 JP JP15699381A patent/JPS5857399A/ja active Granted
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5859921A (ja) * | 1981-10-02 | 1983-04-09 | Rooto Seiyaku Kk | アマチヤヅルサポニンを含有する抗癌剤 |
| WO1997031013A1 (en) * | 1996-02-22 | 1997-08-28 | Il Hwa Co., Ltd. | Metabolites of ginseng saponins by human intestinal bacteria and its preparation for an anticancer |
| WO2011002033A1 (ja) | 2009-06-30 | 2011-01-06 | ライオン株式会社 | 糖代謝改善剤及び糖代謝改善組成物 |
| KR20160132134A (ko) | 2009-06-30 | 2016-11-16 | 라이온 가부시키가이샤 | 당 대사 개선제 및 당 대사 개선 조성물 |
| WO2011074377A1 (ja) | 2009-12-14 | 2011-06-23 | ライオン株式会社 | プロトパナキサトリオール及びプロトパナキサジオール含有組成物 |
| KR20120103634A (ko) | 2009-12-14 | 2012-09-19 | 라이온 가부시키가이샤 | 프로토파낙사트리올 및 프로토파낙사디올 함유 조성물 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0128759B2 (enrdf_load_stackoverflow) | 1989-06-05 |
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