JPS5829320B2 - スピロラクトンステロイド ノ シンキナ セイゾウホウ - Google Patents
スピロラクトンステロイド ノ シンキナ セイゾウホウInfo
- Publication number
- JPS5829320B2 JPS5829320B2 JP49014627A JP1462774A JPS5829320B2 JP S5829320 B2 JPS5829320 B2 JP S5829320B2 JP 49014627 A JP49014627 A JP 49014627A JP 1462774 A JP1462774 A JP 1462774A JP S5829320 B2 JPS5829320 B2 JP S5829320B2
- Authority
- JP
- Japan
- Prior art keywords
- general formula
- product
- compound
- following general
- alkyl group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7304057A FR2216273B1 (es) | 1973-02-06 | 1973-02-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS49109365A JPS49109365A (es) | 1974-10-17 |
JPS5829320B2 true JPS5829320B2 (ja) | 1983-06-22 |
Family
ID=9114388
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP49014627A Expired JPS5829320B2 (ja) | 1973-02-06 | 1974-02-06 | スピロラクトンステロイド ノ シンキナ セイゾウホウ |
Country Status (14)
Country | Link |
---|---|
US (1) | US3897417A (es) |
JP (1) | JPS5829320B2 (es) |
AT (1) | AT336811B (es) |
BE (1) | BE810643A (es) |
CA (1) | CA1026318A (es) |
CH (2) | CH609710A5 (es) |
DK (1) | DK134818B (es) |
ES (2) | ES422921A1 (es) |
FR (1) | FR2216273B1 (es) |
GB (1) | GB1451843A (es) |
IE (1) | IE39329B1 (es) |
LU (1) | LU69328A1 (es) |
NL (1) | NL179288C (es) |
SE (2) | SE399270B (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4058522A (en) * | 1973-07-09 | 1977-11-15 | Richter Gedeon Vegyeszeti Gyar Rt. | Steroids effective against heavy-metal poisoning |
IT1130924B (it) * | 1980-03-06 | 1986-06-18 | Secifarma Spa | Procedimento per la preparazione di spironolattone micronizzato |
US4501695A (en) * | 1983-05-16 | 1985-02-26 | The Upjohn Company | Spironalactone process |
EA009176B1 (ru) | 1995-12-11 | 2007-12-28 | Дж.Д.Серл Энд Ко. | Способ получения 7-альфа-карбоксил-9,11-эпоксистероидов и промежуточных продуктов, используемых для их получения, и общий способ эпоксидирования по олефиновым двойным связям |
US6887991B1 (en) | 1996-12-11 | 2005-05-03 | G. D. Searle & Company | Processes for preparation of 9, 11-epoxy steroids and intermediates useful therein |
DK0944644T3 (da) | 1996-12-11 | 2003-02-03 | Searle & Co | Fremgangsmåde til fremstilling af 3-keto-7-alfa-alkoxycarbonyl-delta-4,5-steroider og mellemprodukter, som er nyttite derfor |
CA2480151A1 (en) * | 2002-03-22 | 2003-10-09 | Pharmacia Corporation | C-17 spirolactonization and 6,7 oxidation of steroids |
US7235655B2 (en) * | 2002-03-22 | 2007-06-26 | Pharmacia & Upjohn Company | Processes to prepare eplerenone |
DE102005049393B4 (de) * | 2005-10-15 | 2019-08-08 | Kennametal Widia Produktions Gmbh & Co. Kg | Verfahren zur Herstellung eines beschichteten Substratkörpers, Substratkörper mit einer Beschichtung und Verwendung des beschichteten Substratkörpers |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1329570A (fr) * | 1959-12-10 | 1963-06-14 | Searle & Co | Procédé de préparation des lactones d'alcanoylthio-17alpha-carboxyéthyl-17bêta-hydroxy-3-oxoandrostènes |
US3257390A (en) * | 1963-06-12 | 1966-06-21 | Merck & Co Inc | Ring a unsaturated 21-hydroxy-3-oxo-17alpha-pregnane-17-carboxylic acid lactone diuretic agents |
US3300489A (en) * | 1964-07-24 | 1967-01-24 | Smith Kline French Lab | Steroidal c-17 spirolactones and processes and intermediates used in the preparation thereof |
-
1973
- 1973-02-06 FR FR7304057A patent/FR2216273B1/fr not_active Expired
-
1974
- 1974-02-01 US US438601A patent/US3897417A/en not_active Expired - Lifetime
- 1974-02-05 ES ES422921A patent/ES422921A1/es not_active Expired
- 1974-02-05 BE BE140580A patent/BE810643A/xx unknown
- 1974-02-05 CA CA191,844A patent/CA1026318A/en not_active Expired
- 1974-02-05 CH CH385975A patent/CH609710A5/xx not_active IP Right Cessation
- 1974-02-05 LU LU69328A patent/LU69328A1/xx unknown
- 1974-02-05 CH CH158474A patent/CH595399A5/xx not_active IP Right Cessation
- 1974-02-05 SE SE7401494A patent/SE399270B/xx not_active IP Right Cessation
- 1974-02-06 IE IE226/74A patent/IE39329B1/xx unknown
- 1974-02-06 NL NLAANVRAGE7401656,A patent/NL179288C/xx not_active IP Right Cessation
- 1974-02-06 AT AT92174A patent/AT336811B/de not_active IP Right Cessation
- 1974-02-06 DK DK62574AA patent/DK134818B/da not_active IP Right Cessation
- 1974-02-06 JP JP49014627A patent/JPS5829320B2/ja not_active Expired
- 1974-02-06 GB GB545174A patent/GB1451843A/en not_active Expired
-
1976
- 1976-01-07 ES ES444112A patent/ES444112A1/es not_active Expired
-
1977
- 1977-06-03 SE SE7706509A patent/SE440782B/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CH595399A5 (es) | 1978-02-15 |
SE399270B (sv) | 1978-02-06 |
LU69328A1 (es) | 1974-09-25 |
US3897417A (en) | 1975-07-29 |
AT336811B (de) | 1977-05-25 |
SE7706509L (sv) | 1977-06-03 |
ATA92174A (de) | 1976-09-15 |
FR2216273B1 (es) | 1977-07-22 |
ES444112A1 (es) | 1977-08-16 |
AU6521174A (en) | 1975-08-07 |
NL179288C (nl) | 1986-08-18 |
NL7401656A (es) | 1974-08-08 |
DK134818C (es) | 1977-06-13 |
ES422921A1 (es) | 1976-09-16 |
SE440782B (sv) | 1985-08-19 |
DK134818B (da) | 1977-01-24 |
GB1451843A (en) | 1976-10-06 |
CH609710A5 (es) | 1979-03-15 |
IE39329B1 (en) | 1978-09-13 |
FR2216273A1 (es) | 1974-08-30 |
CA1026318A (en) | 1978-02-14 |
BE810643A (fr) | 1974-08-05 |
NL179288B (nl) | 1986-03-17 |
JPS49109365A (es) | 1974-10-17 |
IE39329L (en) | 1974-08-06 |
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