ES444112A1 - Un procedimiento de preparacion de espirolactonas esteroi- des. - Google Patents

Un procedimiento de preparacion de espirolactonas esteroi- des.

Info

Publication number
ES444112A1
ES444112A1 ES444112A ES444112A ES444112A1 ES 444112 A1 ES444112 A1 ES 444112A1 ES 444112 A ES444112 A ES 444112A ES 444112 A ES444112 A ES 444112A ES 444112 A1 ES444112 A1 ES 444112A1
Authority
ES
Spain
Prior art keywords
intermediates
preparation
formula
spirolactones
steroidal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES444112A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES444112A1 publication Critical patent/ES444112A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES444112A 1973-02-06 1976-01-07 Un procedimiento de preparacion de espirolactonas esteroi- des. Expired ES444112A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7304057A FR2216273B1 (es) 1973-02-06 1973-02-06

Publications (1)

Publication Number Publication Date
ES444112A1 true ES444112A1 (es) 1977-08-16

Family

ID=9114388

Family Applications (2)

Application Number Title Priority Date Filing Date
ES422921A Expired ES422921A1 (es) 1973-02-06 1974-02-05 Procedimiento de preparacion de espirolactonas esteroides.
ES444112A Expired ES444112A1 (es) 1973-02-06 1976-01-07 Un procedimiento de preparacion de espirolactonas esteroi- des.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES422921A Expired ES422921A1 (es) 1973-02-06 1974-02-05 Procedimiento de preparacion de espirolactonas esteroides.

Country Status (14)

Country Link
US (1) US3897417A (es)
JP (1) JPS5829320B2 (es)
AT (1) AT336811B (es)
BE (1) BE810643A (es)
CA (1) CA1026318A (es)
CH (2) CH595399A5 (es)
DK (1) DK134818B (es)
ES (2) ES422921A1 (es)
FR (1) FR2216273B1 (es)
GB (1) GB1451843A (es)
IE (1) IE39329B1 (es)
LU (1) LU69328A1 (es)
NL (1) NL179288C (es)
SE (2) SE399270B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4058522A (en) * 1973-07-09 1977-11-15 Richter Gedeon Vegyeszeti Gyar Rt. Steroids effective against heavy-metal poisoning
IT1130924B (it) * 1980-03-06 1986-06-18 Secifarma Spa Procedimento per la preparazione di spironolattone micronizzato
US4501695A (en) * 1983-05-16 1985-02-26 The Upjohn Company Spironalactone process
DK0973791T3 (da) 1995-12-11 2007-09-17 Searle Llc Fremgangsmåde til fremstilling af en epoxyforbindelse
WO1998025948A2 (en) 1996-12-11 1998-06-18 G.D. Searle & Co. Processes for preparation of 9,11-epoxy steroids and intermediates useful therein
US6887991B1 (en) * 1996-12-11 2005-05-03 G. D. Searle & Company Processes for preparation of 9, 11-epoxy steroids and intermediates useful therein
KR20040097201A (ko) * 2002-03-22 2004-11-17 파마시아 앤드 업존 캄파니 에플레레논의 제조 방법
US7235655B2 (en) 2002-03-22 2007-06-26 Pharmacia & Upjohn Company Processes to prepare eplerenone
DE102005049393B4 (de) * 2005-10-15 2019-08-08 Kennametal Widia Produktions Gmbh & Co. Kg Verfahren zur Herstellung eines beschichteten Substratkörpers, Substratkörper mit einer Beschichtung und Verwendung des beschichteten Substratkörpers

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1329570A (fr) * 1959-12-10 1963-06-14 Searle & Co Procédé de préparation des lactones d'alcanoylthio-17alpha-carboxyéthyl-17bêta-hydroxy-3-oxoandrostènes
US3257390A (en) * 1963-06-12 1966-06-21 Merck & Co Inc Ring a unsaturated 21-hydroxy-3-oxo-17alpha-pregnane-17-carboxylic acid lactone diuretic agents
US3300489A (en) * 1964-07-24 1967-01-24 Smith Kline French Lab Steroidal c-17 spirolactones and processes and intermediates used in the preparation thereof

Also Published As

Publication number Publication date
SE399270B (sv) 1978-02-06
CH609710A5 (es) 1979-03-15
DK134818C (es) 1977-06-13
FR2216273A1 (es) 1974-08-30
AT336811B (de) 1977-05-25
ES422921A1 (es) 1976-09-16
JPS5829320B2 (ja) 1983-06-22
JPS49109365A (es) 1974-10-17
NL179288C (nl) 1986-08-18
GB1451843A (en) 1976-10-06
FR2216273B1 (es) 1977-07-22
AU6521174A (en) 1975-08-07
BE810643A (fr) 1974-08-05
IE39329L (en) 1974-08-06
SE7706509L (sv) 1977-06-03
LU69328A1 (es) 1974-09-25
CA1026318A (en) 1978-02-14
SE440782B (sv) 1985-08-19
IE39329B1 (en) 1978-09-13
NL7401656A (es) 1974-08-08
NL179288B (nl) 1986-03-17
ATA92174A (de) 1976-09-15
DK134818B (da) 1977-01-24
CH595399A5 (es) 1978-02-15
US3897417A (en) 1975-07-29

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980302