JPS5826268A - 懸濁液中の粒子と液体との間の反応物質の分布の分析法 - Google Patents

懸濁液中の粒子と液体との間の反応物質の分布の分析法

Info

Publication number
JPS5826268A
JPS5826268A JP57125189A JP12518982A JPS5826268A JP S5826268 A JPS5826268 A JP S5826268A JP 57125189 A JP57125189 A JP 57125189A JP 12518982 A JP12518982 A JP 12518982A JP S5826268 A JPS5826268 A JP S5826268A
Authority
JP
Japan
Prior art keywords
liquid
suspension
image
particles
reactants
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57125189A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0526143B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html
Inventor
フレツド・エイチ・ダインドウフア
ジエ−ムス・ア−ル・ガングワ−
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INTAANATIONAL RIMOOTO IMEEJING
INTAANATIONAL RIMOOTO IMEEJINGU SYSTEMS
Original Assignee
INTAANATIONAL RIMOOTO IMEEJING
INTAANATIONAL RIMOOTO IMEEJINGU SYSTEMS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INTAANATIONAL RIMOOTO IMEEJING, INTAANATIONAL RIMOOTO IMEEJINGU SYSTEMS filed Critical INTAANATIONAL RIMOOTO IMEEJING
Publication of JPS5826268A publication Critical patent/JPS5826268A/ja
Publication of JPH0526143B2 publication Critical patent/JPH0526143B2/ja
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1468—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
    • G01N15/147—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/804—Radioisotope, e.g. radioimmunoassay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
JP57125189A 1981-07-22 1982-07-20 懸濁液中の粒子と液体との間の反応物質の分布の分析法 Granted JPS5826268A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/286,027 US4476231A (en) 1981-07-22 1981-07-22 Method of analyzing the distribution of a reagent between particles and liquid in a suspension
US286027 2002-11-01

Publications (2)

Publication Number Publication Date
JPS5826268A true JPS5826268A (ja) 1983-02-16
JPH0526143B2 JPH0526143B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-04-15

Family

ID=23096734

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57125189A Granted JPS5826268A (ja) 1981-07-22 1982-07-20 懸濁液中の粒子と液体との間の反応物質の分布の分析法

Country Status (7)

Country Link
US (1) US4476231A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5826268A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU554208B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1182746A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3226332C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2510258B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2103362B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60128369A (ja) * 1983-11-07 1985-07-09 アリリツクス　インコ−ポレ−テツド 定性的酵素免疫検定を遂行する為の装置及び方法
JPS6113155A (ja) * 1984-06-21 1986-01-21 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 個々の金属粒子を可視化する方法
JPS61132868A (ja) * 1984-12-03 1986-06-20 Olympus Optical Co Ltd 免疫学的分析方法
JPS61132870A (ja) * 1984-12-03 1986-06-20 Olympus Optical Co Ltd 免疫学的分析方法
JPS61132869A (ja) * 1984-12-03 1986-06-20 Olympus Optical Co Ltd 免疫学的分析方法
JPH02170053A (ja) * 1988-12-23 1990-06-29 Meiji Seika Kaisha Ltd 微生物の検出方法及び装置
JPH08136546A (ja) * 1994-11-15 1996-05-31 Bio Sensor Kenkyusho:Kk 物質分析法
US5690895A (en) * 1993-01-26 1997-11-25 Hitachi, Ltd. Flow cell apparatus
JP2011128170A (ja) * 2007-06-21 2011-06-30 Gen-Probe Inc 検出室の内容物を混合する機器および方法

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USRE34405E (en) * 1983-08-01 1993-10-12 Abbott Laboratories Determination of analytes in particle-containing medium
US5096807A (en) * 1985-03-06 1992-03-17 Murex Corporation Imaging immunoassay detection system with background compensation and its use
GB8513538D0 (en) * 1985-05-29 1985-07-03 Mackay C D Electrophoresis
US4896966A (en) * 1986-08-15 1990-01-30 Hamilton-Thorn Research Motility scanner and method
US5149661A (en) * 1988-06-08 1992-09-22 Sarasep, Inc. Fluid analysis with particulate reagent suspension
US5301671A (en) * 1991-09-17 1994-04-12 The United States Of America As Represented By The Department Of Health And Human Services Two- and three-dimensional autoradiographic imaging utilizing charge coupled devices
FR2693740B1 (fr) * 1992-07-17 1994-10-14 Univ Joseph Fourier Procédé de détection tissulaire ou cellulaire mettant en Óoeuvre des réactifs chimiluminescents.
US5674698A (en) * 1992-09-14 1997-10-07 Sri International Up-converting reporters for biological and other assays using laser excitation techniques
US5698397A (en) * 1995-06-07 1997-12-16 Sri International Up-converting reporters for biological and other assays using laser excitation techniques
US6399397B1 (en) 1992-09-14 2002-06-04 Sri International Up-converting reporters for biological and other assays using laser excitation techniques
US6159686A (en) * 1992-09-14 2000-12-12 Sri International Up-converting reporters for biological and other assays
US5736410A (en) 1992-09-14 1998-04-07 Sri International Up-converting reporters for biological and other assays using laser excitation techniques
EP0731951B1 (en) * 1993-02-26 2000-07-05 E-Y Laboratories, Inc. Optical specimen analysis system and method
ES2089638T3 (es) * 1993-06-03 1996-10-01 Bernd Dr Med Burkhardt Deteccion de antigenos viricos o bacterianos por medio de citometria en medio fluido.
JPH07120375A (ja) * 1993-10-21 1995-05-12 Hitachi Ltd フロー式粒子画像解析方法及び装置
EP0745327A1 (en) 1995-05-29 1996-12-04 Symbollon Corporation Method for inactivating pathogens
US5814468A (en) * 1996-03-27 1998-09-29 Coulter International Corp. Methods of enumerating receptor molecules for specific binding partners on formed bodies and in solution
DE19621312A1 (de) 1996-05-28 1997-12-04 Bayer Ag Maskierung der Hintergrundfluoreszenz und Signalverstärkung bei der optischen Analyse biologisch medizinischer Assays
JP2002502980A (ja) * 1998-02-10 2002-01-29 イーワイ ラボラトリーズ インコーポレイテッド 試料ホルダ起伏形状を補償し且つシステム・ノイズのロック除去を行う反射測定システム
US20030133119A1 (en) * 2002-01-17 2003-07-17 Bachur Nicholas R. Rapid imaging of particles in a large fluid volume through flow cell imaging
US7232689B2 (en) * 2002-03-11 2007-06-19 Pawliszyn Janusz B Calibration procedure for investigating biological systems
US9870907B2 (en) 2002-03-11 2018-01-16 Jp Scientific Limited Probe for extraction of molecules of interest from a sample
US8598325B2 (en) 2002-03-11 2013-12-03 Janusz B. Pawliszyn Solid-phase microextraction coatings and methods for their preparation
DE60325180D1 (de) * 2002-03-11 2009-01-22 Janusz B Pawliszyn Mikrovorrichtungen zur untersuchung von biologischen systemen
WO2017193213A1 (en) 2016-05-10 2017-11-16 Jp Scientific Limited System and method for desorbing and detecting an analyte sorbed on a solid phase microextraction device
US20090026122A1 (en) * 2002-03-11 2009-01-29 Janusz Biocompatible solid-phase microextraction coatings and methods for their preparation
US9733234B2 (en) 2002-03-11 2017-08-15 Jp Scientific Limited Probe for extraction of molecules of interest from a sample
US7391028B1 (en) 2005-02-28 2008-06-24 Advanced Fuel Research, Inc. Apparatus and method for detection of radiation
US8011133B2 (en) * 2007-06-27 2011-09-06 Pioneer Hi-Bred International, Inc. Method and apparatus of high-throughput pollen extraction, counting, and use of counted pollen for characterizing a plant
EP2163239A1 (de) * 2008-05-27 2010-03-17 Qiagen GmbH Produkte, die Biopartikel enthalten, Verfahren zu ihrer Herstellung
KR20100110121A (ko) * 2009-04-02 2010-10-12 삼성전자주식회사 이미지 왜곡 보정 방법
JP5822168B2 (ja) * 2010-05-31 2015-11-24 ベーリンガー インゲルハイム マイクロパーツ ゲゼルシャフト ミットベシュレンクテル ハフツングＢｏｅｈｒｉｎｇｅｒ Ｉｎｇｅｌｈｅｉｍ ｍｉｃｒｏＰａｒｔｓ ＧｍｂＨ 光学検査方法及び器具
WO2013070846A1 (en) 2011-11-11 2013-05-16 Pioneer Hi-Bred International, Inc. Large scale method for dispensing grains of pollen
WO2014075080A1 (en) 2012-11-12 2014-05-15 Image Insight Inc. Crowd-sourced hardware calibration
JP6930978B2 (ja) 2016-03-02 2021-09-01 ジェイ・ピィ・サイエンティフィック・リミテッドＪｐ Ｓｃｉｅｎｔｉｆｉｃ Ｌｉｍｉｔｅｄ 固相マイクロ抽出用コーティング
US10278656B2 (en) 2016-05-09 2019-05-07 Image Insight, Inc. Medical devices for diagnostic imaging

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4874292A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1971-12-23 1973-10-06
US4097845A (en) * 1976-11-01 1978-06-27 Rush-Presbyterian-St. Luke's Medical Center Method of and an apparatus for automatic classification of red blood cells

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US3088875A (en) * 1959-10-27 1963-05-07 Hyland Lab Immunological diagnostics utilizing polystyrene latex particles of 0.15 to 0.25 micron
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US3520609A (en) * 1966-07-21 1970-07-14 Pfizer & Co C Method and apparatus for detecting agglutination reactions
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GB2045431B (en) * 1979-02-26 1983-04-20 Technicon Instr Immunoassay utilising two particulate reagents
US4318886A (en) * 1979-11-19 1982-03-09 Nippon Kogaku K.K. Automatic HLA typing apparatus
US4338024A (en) * 1980-05-02 1982-07-06 International Remote Imaging Systems, Inc. Flow analyzer and system for analysis of fluids with particles

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4874292A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1971-12-23 1973-10-06
US4097845A (en) * 1976-11-01 1978-06-27 Rush-Presbyterian-St. Luke's Medical Center Method of and an apparatus for automatic classification of red blood cells

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60128369A (ja) * 1983-11-07 1985-07-09 アリリツクス　インコ−ポレ−テツド 定性的酵素免疫検定を遂行する為の装置及び方法
JPS6113155A (ja) * 1984-06-21 1986-01-21 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 個々の金属粒子を可視化する方法
JPS61132868A (ja) * 1984-12-03 1986-06-20 Olympus Optical Co Ltd 免疫学的分析方法
JPS61132870A (ja) * 1984-12-03 1986-06-20 Olympus Optical Co Ltd 免疫学的分析方法
JPS61132869A (ja) * 1984-12-03 1986-06-20 Olympus Optical Co Ltd 免疫学的分析方法
JPH02170053A (ja) * 1988-12-23 1990-06-29 Meiji Seika Kaisha Ltd 微生物の検出方法及び装置
US5690895A (en) * 1993-01-26 1997-11-25 Hitachi, Ltd. Flow cell apparatus
JPH08136546A (ja) * 1994-11-15 1996-05-31 Bio Sensor Kenkyusho:Kk 物質分析法
JP2011128170A (ja) * 2007-06-21 2011-06-30 Gen-Probe Inc 検出室の内容物を混合する機器および方法

Also Published As

Publication number Publication date
US4476231A (en) 1984-10-09
DE3226332A1 (de) 1983-04-07
FR2510258B1 (fr) 1986-03-28
GB2103362A (en) 1983-02-16
GB2103362B (en) 1985-09-11
AU554208B2 (en) 1986-08-14
AU8608782A (en) 1983-01-27
JPH0526143B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-04-15
CA1182746A (en) 1985-02-19
DE3226332C2 (de) 1996-02-29
FR2510258A1 (fr) 1983-01-28

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