JPS58210011A - 抗腫瘍剤 - Google Patents
抗腫瘍剤Info
- Publication number
- JPS58210011A JPS58210011A JP9232082A JP9232082A JPS58210011A JP S58210011 A JPS58210011 A JP S58210011A JP 9232082 A JP9232082 A JP 9232082A JP 9232082 A JP9232082 A JP 9232082A JP S58210011 A JPS58210011 A JP S58210011A
- Authority
- JP
- Japan
- Prior art keywords
- lactone
- dihydroxyvitamin
- 1alpha
- antitumor agent
- vitro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002246 antineoplastic agent Substances 0.000 title claims abstract 4
- 239000004480 active ingredient Substances 0.000 claims abstract 3
- 206010028980 Neoplasm Diseases 0.000 claims 1
- GMRQFYUYWCNGIN-NKMMMXOESA-N calcitriol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](CCCC(C)(C)O)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C GMRQFYUYWCNGIN-NKMMMXOESA-N 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- WMYIVSWWSRCZFA-RWVJFQLJSA-N 1,25-Dihydroxyvitamin D3-26,23-lactone Chemical compound C([C@@H](C)[C@@H]1[C@]2(CCCC(/[C@@H]2CC1)=C\C=C\1C([C@@H](O)C[C@H](O)C/1)=C)C)[C@H]1C[C@@](C)(O)C(=O)O1 WMYIVSWWSRCZFA-RWVJFQLJSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000000445 cytocidal effect Effects 0.000 abstract 2
- 238000000338 in vitro Methods 0.000 abstract 2
- 206010035226 Plasma cell myeloma Diseases 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 208000032839 leukemia Diseases 0.000 abstract 1
- 201000000050 myeloid neoplasm Diseases 0.000 abstract 1
Landscapes
- Furan Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9232082A JPS58210011A (ja) | 1982-05-31 | 1982-05-31 | 抗腫瘍剤 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9232082A JPS58210011A (ja) | 1982-05-31 | 1982-05-31 | 抗腫瘍剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS58210011A true JPS58210011A (ja) | 1983-12-07 |
JPH0220613B2 JPH0220613B2 (enrdf_load_stackoverflow) | 1990-05-10 |
Family
ID=14051093
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP9232082A Granted JPS58210011A (ja) | 1982-05-31 | 1982-05-31 | 抗腫瘍剤 |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS58210011A (enrdf_load_stackoverflow) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3541934A1 (de) * | 1984-11-29 | 1986-06-05 | F. Hoffmann-La Roche & Co Ag, Basel | Cholecalciferolderivate |
EP0712843A4 (en) * | 1994-06-07 | 1996-11-13 | Teijin Ltd | VITAMIN D3 DERIVATIVE AND PROCESS FOR PRODUCING THE SAME |
US5604257A (en) * | 1993-02-05 | 1997-02-18 | Teijin Limited | Lactone compound and process of production thereof |
-
1982
- 1982-05-31 JP JP9232082A patent/JPS58210011A/ja active Granted
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3541934A1 (de) * | 1984-11-29 | 1986-06-05 | F. Hoffmann-La Roche & Co Ag, Basel | Cholecalciferolderivate |
US5604257A (en) * | 1993-02-05 | 1997-02-18 | Teijin Limited | Lactone compound and process of production thereof |
EP0712843A4 (en) * | 1994-06-07 | 1996-11-13 | Teijin Ltd | VITAMIN D3 DERIVATIVE AND PROCESS FOR PRODUCING THE SAME |
US5719297A (en) * | 1994-06-07 | 1998-02-17 | Teijin Limited | Vitamin D3 derivatives and production process thereof |
EP0854139A3 (en) * | 1994-06-07 | 1998-09-23 | Teijin Limited | Vitamin D3 derivative and production process thereof |
EP0854138A3 (en) * | 1994-06-07 | 1998-09-23 | Teijin Limited | Vitamin D3 derivative and production process thereof |
US5986112A (en) * | 1994-06-07 | 1999-11-16 | Teijin Limited | Vitamin D3 derivative and production process thereof |
US6177586B1 (en) | 1994-06-07 | 2001-01-23 | Teijin Limited | Vitamin D3 derivative and production process thereof |
Also Published As
Publication number | Publication date |
---|---|
JPH0220613B2 (enrdf_load_stackoverflow) | 1990-05-10 |
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