JPS58124764A - 光学活性チオ−ル化合物の製造法 - Google Patents

光学活性チオ−ル化合物の製造法

Info

Publication number
JPS58124764A
JPS58124764A JP57007803A JP780382A JPS58124764A JP S58124764 A JPS58124764 A JP S58124764A JP 57007803 A JP57007803 A JP 57007803A JP 780382 A JP780382 A JP 780382A JP S58124764 A JPS58124764 A JP S58124764A
Authority
JP
Japan
Prior art keywords
methylpropanoyl
reaction
compound
proline
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57007803A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6340424B2 (enExample
Inventor
Takehisa Ohashi
武久 大橋
Masami Shimazaki
島崎　正美
Kenji Nomura
野村　憲二
Kyoji Nose
能勢　恭司
Kiyoshi Watanabe
清 渡辺
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kanegafuchi Chemical Industry Co Ltd
Original Assignee
Kanegafuchi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanegafuchi Chemical Industry Co Ltd filed Critical Kanegafuchi Chemical Industry Co Ltd
Priority to JP57007803A priority Critical patent/JPS58124764A/ja
Priority to US06/457,377 priority patent/US4460780A/en
Priority to EP83100420A priority patent/EP0084380B1/en
Priority to DE8383100420T priority patent/DE3363447D1/de
Priority to IE105/83A priority patent/IE54877B1/en
Publication of JPS58124764A publication Critical patent/JPS58124764A/ja
Publication of JPS6340424B2 publication Critical patent/JPS6340424B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
JP57007803A 1982-01-20 1982-01-20 光学活性チオ−ル化合物の製造法 Granted JPS58124764A (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP57007803A JPS58124764A (ja) 1982-01-20 1982-01-20 光学活性チオ−ル化合物の製造法
US06/457,377 US4460780A (en) 1982-01-20 1983-01-12 Process for preparation of optically active thiol compounds
EP83100420A EP0084380B1 (en) 1982-01-20 1983-01-18 Process for the preparation of optically active thiol compounds
DE8383100420T DE3363447D1 (en) 1982-01-20 1983-01-18 Process for the preparation of optically active thiol compounds
IE105/83A IE54877B1 (en) 1982-01-20 1983-01-19 Process for the preparation of optically active thiol compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57007803A JPS58124764A (ja) 1982-01-20 1982-01-20 光学活性チオ−ル化合物の製造法

Publications (2)

Publication Number Publication Date
JPS58124764A true JPS58124764A (ja) 1983-07-25
JPS6340424B2 JPS6340424B2 (enExample) 1988-08-11

Family

ID=11675779

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57007803A Granted JPS58124764A (ja) 1982-01-20 1982-01-20 光学活性チオ−ル化合物の製造法

Country Status (5)

Country Link
US (1) US4460780A (enExample)
EP (1) EP0084380B1 (enExample)
JP (1) JPS58124764A (enExample)
DE (1) DE3363447D1 (enExample)
IE (1) IE54877B1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU208954B (en) * 1990-09-21 1994-02-28 Egyt Gyogyszervegyeszeti Gyar Process for producing 1-(3-mercapto-(2s)-methyl-1-oxo-propyl)-l-prolyn
KR860001391B1 (ko) * 1984-07-23 1986-09-22 보령제약 주식회사 피롤리딘 유도체의 제조방법
KR870001570B1 (ko) * 1984-12-19 1987-09-04 보령제약 주식회사 피롤리딘 유도체의 제조방법
KR870001569B1 (ko) * 1985-02-11 1987-09-04 보령제약 주식회사 피롤리딘 유도체의 제조방법
US5026873A (en) * 1989-11-06 1991-06-25 E. R. Squibb & Sons, Inc. Process for direct isolation of captopril
KR940005014B1 (ko) * 1991-11-07 1994-06-09 보령제약 주식회사 피롤리딘카르복실산 유도체의 제조방법
CN107652215A (zh) * 2017-09-19 2018-02-02 重庆西南制药二厂有限责任公司 一种卡托普利的制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56100760A (en) * 1979-12-29 1981-08-12 Egyt Gyogyszervegyeszeti Gyar Manufacture of 11*33mercaptoo*2s** methylpropionyl**pyrrolidinee*2s**carboxylic acid

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56100760A (en) * 1979-12-29 1981-08-12 Egyt Gyogyszervegyeszeti Gyar Manufacture of 11*33mercaptoo*2s** methylpropionyl**pyrrolidinee*2s**carboxylic acid

Also Published As

Publication number Publication date
IE830105L (en) 1983-07-20
JPS6340424B2 (enExample) 1988-08-11
DE3363447D1 (en) 1986-06-19
US4460780A (en) 1984-07-17
EP0084380B1 (en) 1986-05-14
EP0084380A1 (en) 1983-07-27
IE54877B1 (en) 1990-03-14

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