JPS5771397A - Preparation of l-tryptophan by fermentation method - Google Patents

Preparation of l-tryptophan by fermentation method

Info

Publication number
JPS5771397A
JPS5771397A JP56130346A JP13034681A JPS5771397A JP S5771397 A JPS5771397 A JP S5771397A JP 56130346 A JP56130346 A JP 56130346A JP 13034681 A JP13034681 A JP 13034681A JP S5771397 A JPS5771397 A JP S5771397A
Authority
JP
Japan
Prior art keywords
tryptophan
bacteria
plasmid
type trp
trp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56130346A
Other languages
English (en)
Other versions
JPH0759199B2 (ja
Inventor
Emu Andaason Debuido
Emu Haaman Kurausu
Eru Somaabuiru Ronarudo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Publication of JPS5771397A publication Critical patent/JPS5771397A/ja
Publication of JPH0759199B2 publication Critical patent/JPH0759199B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/227—Tryptophan
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
JP56130346A 1980-08-22 1981-08-21 発酵法によるｌ−トリプトフアンの製造法 Expired - Lifetime JPH0759199B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US180296 1980-08-22
US06/180,296 US4371614A (en) 1980-08-22 1980-08-22 E.Coli bacteria carrying recombinant plasmids and their use in the fermentative production of L-tryptophan

Publications (2)

Publication Number Publication Date
JPS5771397A true JPS5771397A (en) 1982-05-04
JPH0759199B2 JPH0759199B2 (ja) 1995-06-28

Family

ID=22659930

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56130346A Expired - Lifetime JPH0759199B2 (ja) 1980-08-22 1981-08-21 発酵法によるｌ−トリプトフアンの製造法

Country Status (2)

Country Link
US (1) US4371614A (ja)
JP (1) JPH0759199B2 (ja)

Cited By (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5780398A (en) * 1980-11-05 1982-05-19 Sanraku Inc Plasmid produced by genetic manipulation, coliform bacillus having the same and preparation of tryptophan with said bacillus
US4588687A (en) * 1981-11-24 1986-05-13 Ajinomoto Company Incorporated Method for producing L-tryptophan by fermentation
JPS6196990A (ja) * 1984-10-19 1986-05-15 Ajinomoto Co Inc Ｌ−トリプトフアンの製造法
JPS61247392A (ja) * 1985-02-04 1986-11-04 エンジニツクス　インコ−ポレ−テツド ２種またはより多くのアミノ酸を同時に産生できる組換え微生物
JPS62195294A (ja) * 1986-02-19 1987-08-28 Ajinomoto Co Inc 発酵法によるｌ−トリプトフアンの製造法
JP2005523696A (ja) * 2002-04-23 2005-08-11 カーギル，インコーポレイティド ポリペプチド及び生合成経路
WO2007100009A1 (ja) 2006-03-03 2007-09-07 Ajinomoto Co., Inc. Ｌ－アミノ酸の製造法
WO2007114465A1 (ja) 2006-03-30 2007-10-11 Ajinomoto Co., Inc. メタノール資化性細菌を用いたカルボン酸の製造法
WO2007125954A1 (ja) 2006-04-28 2007-11-08 Ajinomoto Co., Inc. Ｌ－アミノ酸を生産する微生物及びｌ－アミノ酸の製造法
WO2008044409A1 (en) 2006-10-10 2008-04-17 Ajinomoto Co., Inc. Method for production of l-amino acid
WO2008075483A1 (ja) 2006-12-19 2008-06-26 Ajinomoto Co., Inc. Ｌ－アミノ酸の製造法
WO2008090770A1 (ja) 2007-01-22 2008-07-31 Ajinomoto Co., Inc. Ｌ－アミノ酸を生産する微生物及びｌ－アミノ酸の製造法
WO2008093829A1 (ja) 2007-02-01 2008-08-07 Ajinomoto Co., Inc. Ｌ－アミノ酸の製造法
WO2008102861A1 (ja) 2007-02-22 2008-08-28 Ajinomoto Co., Inc. Ｌ－アミノ酸の製造法
WO2008102572A1 (ja) 2007-02-20 2008-08-28 Ajinomoto Co., Inc. Ｌ－アミノ酸または核酸の製造方法
WO2009031565A1 (ja) 2007-09-04 2009-03-12 Ajinomoto Co., Inc. アミノ酸生産微生物及びアミノ酸の製造法
EP2055771A2 (en) 2006-03-23 2009-05-06 Ajinomoto Co., Inc. A method for producing an L-amino acid using bacterium of the Enterobacteriaceae family with attenuated expression of a gene coding for small RNA
DE102008049533A1 (de) 2007-09-27 2009-06-18 Ajinomoto Co., Inc. Verfahren zum Herstellen von Aminosäuren unter Verwendung eines Bakteriums der Familie Enterobacteriaceae
WO2009088049A1 (ja) 2008-01-10 2009-07-16 Ajinomoto Co., Inc. 発酵法による目的物質の製造法
WO2009093703A1 (ja) 2008-01-23 2009-07-30 Ajinomoto Co., Inc. Ｌ-アミノ酸の製造法
EP2093291A1 (en) 2008-02-19 2009-08-26 Ajinomoto Co., Inc. A method for constructing an operon containing translationally coupled genes
WO2010027045A1 (ja) 2008-09-08 2010-03-11 味の素株式会社 Ｌ－アミノ酸を生産する微生物及びｌ－アミノ酸の製造法
WO2010084995A2 (en) 2009-01-23 2010-07-29 Ajinomoto Co.,Inc. A method for producing an l-amino acid
WO2011013707A1 (ja) 2009-07-29 2011-02-03 味の素株式会社 Ｌ-アミノ酸の製造法
WO2011024555A1 (ja) 2009-08-28 2011-03-03 味の素株式会社 Ｌ－アミノ酸の製造法
WO2011055710A1 (ja) 2009-11-06 2011-05-12 味の素株式会社 Ｌ－アミノ酸の製造法
EP2345667A2 (en) 2010-01-15 2011-07-20 Ajinomoto Co., Inc. A method for producing an L-amino acid using a bacterium of the enterobacteriaceae family
WO2011096554A1 (ja) 2010-02-08 2011-08-11 味の素株式会社 変異型ｒｐｓＡ遺伝子及びＬ－アミノ酸の製造法
WO2011102305A2 (en) 2010-02-18 2011-08-25 Ajinomoto Co.,Inc. A METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE Enterobacteriaceae FAMILY HAVING A MUTANT ADENYLATE CYCLASE
WO2012011595A1 (en) 2010-07-21 2012-01-26 Ajinomoto Co.,Inc. A METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY HAVING ATTENUATED EXPRESSION OF THE astCADBE OPERON
WO2012011596A1 (en) 2010-07-21 2012-01-26 Ajinomoto Co.,Inc. A method for producing an l- amino acid using a bacterium of the enterobacteriaceae family with enhanced expression of the bssr gene
EP2460873A1 (en) 2006-12-12 2012-06-06 Ajinomoto Co., Inc. A method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family with attenuated expression of any of the cynT, cynS, cynX or cynR genes or a combination thereof
WO2012077739A1 (ja) 2010-12-10 2012-06-14 味の素株式会社 Ｌ－アミノ酸の製造法
EP2559754A2 (en) 2011-08-18 2013-02-20 Ajinomoto Co., Inc. Method for producing an L-amino acid using a bacterium of the family enterobacteriaceae having enhanced expression of the flagella formation and motility cascade genes
EP2796560A1 (en) 2013-04-23 2014-10-29 Ajinomoto Co., Inc. A method for producing an L-amino acid using a bacterium of the family Enterobacteriaceae having attenuated expression of the yjjK gene
WO2015030019A1 (en) 2013-08-30 2015-03-05 Ajinomoto Co.,Inc. A METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE FAMILY ENTEROBACTERIACEAE HAVING ATTENUATED EXPRESSION OF THE znuACB GENE CLUSTER
WO2015041265A1 (ja) 2013-09-17 2015-03-26 味の素株式会社 海藻由来バイオマスからのｌ－アミノ酸の製造方法
WO2015050234A1 (ja) 2013-10-02 2015-04-09 味の素株式会社 アンモニア制御装置およびアンモニア制御方法
WO2015050276A1 (en) 2013-10-02 2015-04-09 Ajinomoto Co.,Inc. A method for producing an l-amino acid using a bacterium of the family enterobacteriaceae having attenuated expression of a phosphate transporter-encoding gene
WO2015060314A1 (ja) 2013-10-21 2015-04-30 味の素株式会社 Ｌ－アミノ酸の製造法
WO2015122544A1 (en) 2014-02-14 2015-08-20 Ajinomoto Co.,Inc. A METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE FAMILY ENTEROBACTERIACEAE HAVING OVEREXPRESSED THE yajL GENE
EP3098319A1 (en) 2015-05-28 2016-11-30 Ajinomoto Co., Inc. A method for producing an l-amino acid using a bacterium of the family enterobacteriaceae having an attenuated expression of a gsha gene
WO2017146195A1 (en) 2016-02-25 2017-08-31 Ajinomoto Co., Inc. A method for producing l-amino acids using a bacterium of the family enterobacteriaceae overexpressing a gene encoding an iron exporter
EP3385389A1 (en) 2017-04-03 2018-10-10 Ajinomoto Co., Inc. Method for producing l-amino acid from fructose
WO2020171227A1 (en) 2019-02-22 2020-08-27 Ajinomoto Co., Inc. METHOD FOR PRODUCING L-AMINO ACIDS USING A BACTERIUM BELONGING TO THE FAMILY Enterobacteriaceae HAVING OVEREXPRESSED ydiJ GENE
WO2020204179A1 (en) 2019-04-05 2020-10-08 Ajinomoto Co., Inc. Method of producing l-amino acids
WO2021060438A1 (en) 2019-09-25 2021-04-01 Ajinomoto Co., Inc. Method for producing l-amino acids by bacterial fermentation

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SE455704B (sv) * 1983-10-24 1988-08-01 Ac Biotechnics Ab Bakteriecell innehallande plasmid med stabiliserad nedervning, plasmid samt forfarande for framstellning av bakteriecellen
US4789702A (en) * 1984-05-18 1988-12-06 Cetus Corporation Feline leukemia virus vaccine
JPH0746994B2 (ja) * 1984-10-04 1995-05-24 味の素株式会社 発酵法によるｌ−アミノ酸の製造法
CA1338664C (en) * 1985-04-10 1996-10-22 Cetus Oncology Corporation Recombinant hosts
US4943531A (en) * 1985-05-06 1990-07-24 The Trustees Of Columbia University In The City Of New York Expression of enzymatically active reverse transcriptase
JPS63500215A (ja) 1985-06-24 1988-01-28 ザ　ヌトラスウイ−ト　カンパニ− アミノ酸合成用の複合プラスミド
EP0232262A4 (en) * 1985-08-15 1989-09-19 Stauffer Chemical Co MICROORGANISM PRODUCING TRYPTOPHANE.
JPH07112431B2 (ja) * 1985-09-06 1995-12-06 味の素株式会社 遺伝子発現調節法
WO1987002984A1 (en) * 1985-11-12 1987-05-21 American Biogenetics Corporation Biogenetic cassette
JP2967996B2 (ja) * 1989-06-06 1999-10-25 協和醗酵工業株式会社 Ｌ―トリプトファンの製造法
DE4232468A1 (de) * 1992-09-28 1994-03-31 Consortium Elektrochem Ind Mikroorganismen für die Produktion von Tryptophan und Verfahren zu ihrer Herstellung
GB2304718B (en) * 1995-09-05 2000-01-19 Degussa The production of tryptophan by the bacterium escherichia coli
US7312247B2 (en) * 2001-03-27 2007-12-25 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
US6495719B2 (en) 2001-03-27 2002-12-17 Circagen Pharmaceutical Histone deacetylase inhibitors
US7314953B2 (en) * 2001-03-27 2008-01-01 Errant Gene Therapeutics, Llc Treatment of lung cells with histone deacetylase inhibitors
US7842727B2 (en) * 2001-03-27 2010-11-30 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
US8026280B2 (en) 2001-03-27 2011-09-27 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
US7057057B2 (en) * 2002-05-22 2006-06-06 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors based on alpha-ketoepoxide compounds
US20030096379A1 (en) * 2001-03-28 2003-05-22 Kilgore James L. Method for producing tryptamine derivatives
ATE470711T1 (de) 2001-11-23 2010-06-15 Ajinomoto Kk Verfahren zur l-aminosäureproduktion mit escherichia
US7572607B2 (en) * 2002-04-23 2009-08-11 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
US8372989B2 (en) 2002-04-23 2013-02-12 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
US20050112260A1 (en) * 2003-08-01 2005-05-26 Cargill, Inc. Monatin tabletop sweetener compositions and methods of making same
ATE360370T1 (de) * 2003-08-14 2007-05-15 Cargill Inc Monatinhaltige kaugummizusammensetzungen und verfahren zu ihrer herstellung
RU2380989C2 (ru) * 2003-08-25 2010-02-10 Карджилл, Инкорпорейтед Питьевая композиция, содержащая монатин, и способы ее получения
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US8153405B2 (en) * 2005-04-20 2012-04-10 Cargill, Incorporated Products and methods for in vivo secretion of monatin
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DE102005018835A1 (de) 2005-04-22 2006-11-02 Degussa Ag Verfahren zur Herstellung von L-Aminosäuren unter Verwendung verbesserter Stämme der Familie Enterobacteriaceae
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US7582455B2 (en) * 2005-04-26 2009-09-01 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
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MX2008011477A (es) 2006-03-07 2008-09-23 Cargill Inc Aldolasas, acidos nucleicos que las codifican y metodos para hacerlas y usarlas.
DE102007051024A1 (de) 2007-03-05 2008-09-11 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
EP1975241A1 (de) 2007-03-29 2008-10-01 Evonik Degussa GmbH Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
DE102007044134A1 (de) 2007-09-15 2009-03-19 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
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Cited By (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5780398A (en) * 1980-11-05 1982-05-19 Sanraku Inc Plasmid produced by genetic manipulation, coliform bacillus having the same and preparation of tryptophan with said bacillus
JPH0226955B2 (ja) * 1980-11-05 1990-06-13 Sanraku Co Ltd
US4588687A (en) * 1981-11-24 1986-05-13 Ajinomoto Company Incorporated Method for producing L-tryptophan by fermentation
JPS6196990A (ja) * 1984-10-19 1986-05-15 Ajinomoto Co Inc Ｌ−トリプトフアンの製造法
JPS61247392A (ja) * 1985-02-04 1986-11-04 エンジニツクス　インコ−ポレ−テツド ２種またはより多くのアミノ酸を同時に産生できる組換え微生物
JPS62195294A (ja) * 1986-02-19 1987-08-28 Ajinomoto Co Inc 発酵法によるｌ−トリプトフアンの製造法
JP2005523696A (ja) * 2002-04-23 2005-08-11 カーギル，インコーポレイティド ポリペプチド及び生合成経路
JP2010004896A (ja) * 2002-04-23 2010-01-14 Cargill Inc ポリペプチド及び生合成経路
JP2011250806A (ja) * 2002-04-23 2011-12-15 Cargill Inc ポリペプチド及び生合成経路
WO2007100009A1 (ja) 2006-03-03 2007-09-07 Ajinomoto Co., Inc. Ｌ－アミノ酸の製造法
EP2055771A2 (en) 2006-03-23 2009-05-06 Ajinomoto Co., Inc. A method for producing an L-amino acid using bacterium of the Enterobacteriaceae family with attenuated expression of a gene coding for small RNA
EP2351830A1 (en) 2006-03-23 2011-08-03 Ajinomoto Co., Inc. A method for producing an L-amino acid using bacterium of the Enterobacteriaceae family with attenuated expression of a gene coding for small RNA
WO2007114465A1 (ja) 2006-03-30 2007-10-11 Ajinomoto Co., Inc. メタノール資化性細菌を用いたカルボン酸の製造法
WO2007125954A1 (ja) 2006-04-28 2007-11-08 Ajinomoto Co., Inc. Ｌ－アミノ酸を生産する微生物及びｌ－アミノ酸の製造法
WO2008044409A1 (en) 2006-10-10 2008-04-17 Ajinomoto Co., Inc. Method for production of l-amino acid
EP2460873A1 (en) 2006-12-12 2012-06-06 Ajinomoto Co., Inc. A method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family with attenuated expression of any of the cynT, cynS, cynX or cynR genes or a combination thereof
WO2008075483A1 (ja) 2006-12-19 2008-06-26 Ajinomoto Co., Inc. Ｌ－アミノ酸の製造法
WO2008090770A1 (ja) 2007-01-22 2008-07-31 Ajinomoto Co., Inc. Ｌ－アミノ酸を生産する微生物及びｌ－アミノ酸の製造法
WO2008093829A1 (ja) 2007-02-01 2008-08-07 Ajinomoto Co., Inc. Ｌ－アミノ酸の製造法
WO2008102572A1 (ja) 2007-02-20 2008-08-28 Ajinomoto Co., Inc. Ｌ－アミノ酸または核酸の製造方法
WO2008102861A1 (ja) 2007-02-22 2008-08-28 Ajinomoto Co., Inc. Ｌ－アミノ酸の製造法
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