JPS5728060A - Pyridazinone derivative - Google Patents
Pyridazinone derivativeInfo
- Publication number
- JPS5728060A JPS5728060A JP10535980A JP10535980A JPS5728060A JP S5728060 A JPS5728060 A JP S5728060A JP 10535980 A JP10535980 A JP 10535980A JP 10535980 A JP10535980 A JP 10535980A JP S5728060 A JPS5728060 A JP S5728060A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- lower alkyl
- ulcer
- expressed
- gastric
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- AAILEWXSEQLMNI-UHFFFAOYSA-N 1h-pyridazin-6-one Chemical class OC1=CC=CN=N1 AAILEWXSEQLMNI-UHFFFAOYSA-N 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 208000025865 Ulcer Diseases 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- 231100000397 ulcer Toxicity 0.000 abstract 2
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 abstract 1
- 206010020601 Hyperchlorhydria Diseases 0.000 abstract 1
- 208000008469 Peptic Ulcer Diseases 0.000 abstract 1
- 208000007107 Stomach Ulcer Diseases 0.000 abstract 1
- 229960001138 acetylsalicylic acid Drugs 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000000718 duodenal ulcer Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 210000004051 gastric juice Anatomy 0.000 abstract 1
- 201000005917 gastric ulcer Diseases 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- NUQKOYSDNPTFGY-UHFFFAOYSA-N methyl n'-[3-[3-(4-chlorophenyl)-6-oxopyridazin-1-yl]propyl]-n-cyanocarbamimidothioate Chemical compound C1=CC(=O)N(CCCN=C(NC#N)SC)N=C1C1=CC=C(Cl)C=C1 NUQKOYSDNPTFGY-UHFFFAOYSA-N 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10535980A JPS5728060A (en) | 1980-07-29 | 1980-07-29 | Pyridazinone derivative |
| AT80304409T ATE3288T1 (de) | 1979-12-05 | 1980-12-05 | 2-substituierte-6-phenyl-3(2h)-pyridazinonderivate, ihre herstellung und sie enthaltende pharmazeutische zusammensetzungen. |
| EP19800304409 EP0030835B1 (en) | 1979-12-05 | 1980-12-05 | Derivatives of 2-substituted-6-phenyl-3(2h)pyridazinone, their production and pharmaceutical compositions containing them |
| ES498263A ES8201553A1 (es) | 1979-12-05 | 1980-12-05 | Procedimiento para la preparacion de derivados de la 6-fenil-3 (2h)-piridacinona 2-substituida |
| DE8080304409T DE3063196D1 (en) | 1979-12-05 | 1980-12-05 | Derivatives of 2-substituted-6-phenyl-3(2h)pyridazinone, their production and pharmaceutical compositions containing them |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10535980A JPS5728060A (en) | 1980-07-29 | 1980-07-29 | Pyridazinone derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5728060A true JPS5728060A (en) | 1982-02-15 |
| JPS6338993B2 JPS6338993B2 (enrdf_load_stackoverflow) | 1988-08-03 |
Family
ID=14405524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10535980A Granted JPS5728060A (en) | 1979-12-05 | 1980-07-29 | Pyridazinone derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5728060A (enrdf_load_stackoverflow) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6242900A (ja) * | 1985-08-20 | 1987-02-24 | 永瀬 慶一 | ポツテングによる装飾品等の製造法 |
-
1980
- 1980-07-29 JP JP10535980A patent/JPS5728060A/ja active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6242900A (ja) * | 1985-08-20 | 1987-02-24 | 永瀬 慶一 | ポツテングによる装飾品等の製造法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6338993B2 (enrdf_load_stackoverflow) | 1988-08-03 |
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