JPS5528907A - Novel 5-(pyridyl)-2-mercaptoimidazole derivative, its preparation,and medicine containing thereof as effective component - Google Patents

Novel 5-(pyridyl)-2-mercaptoimidazole derivative, its preparation,and medicine containing thereof as effective component

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Publication number
JPS5528907A
JPS5528907A JP10088478A JP10088478A JPS5528907A JP S5528907 A JPS5528907 A JP S5528907A JP 10088478 A JP10088478 A JP 10088478A JP 10088478 A JP10088478 A JP 10088478A JP S5528907 A JPS5528907 A JP S5528907A
Authority
JP
Japan
Prior art keywords
pyridyl
novel
preparation
formula
effective component
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10088478A
Other languages
Japanese (ja)
Inventor
Katsuyuki Otsuka
Teruhiko Umetsu
Kazuko Sanai
Tadakatsu Kato
Michio Tanaka
Toshiyoshi Taniguchi
Koji Amamiya
Katsumasa Saga
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kaken Pharmaceutical Co Ltd
Original Assignee
Kaken Pharmaceutical Co Ltd
Kaken Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaken Pharmaceutical Co Ltd, Kaken Chemical Co Ltd filed Critical Kaken Pharmaceutical Co Ltd
Priority to JP10088478A priority Critical patent/JPS5528907A/en
Publication of JPS5528907A publication Critical patent/JPS5528907A/en
Pending legal-status Critical Current

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  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:5-(Pyridyl)-2-mercaptoimidazole derivative expressed by the formula (R1 is 2-pyridyl or 4-pyridyl; R2 is lower alkyl or phenyl optionally substituted with halogen, lower alkyl or lower alkoxy).
EXAMPLE: 1-Methyl-2-mercapto-5-(4'-pyridyl)-imidazole (R1=4'-pyridyl and R2= methyl in the formula).
USE: An antithrombic agent, a blood platelet coagulation suppressing agent, a hypotensor and an antiphlogistic agent having high activity.
PROCESS: 2-Pyridyl or 4-pyridyl-aminomethyl ketone is reacted with an isothiocyanate R2NCS to give the compound expressed by the formula.
COPYRIGHT: (C)1980,JPO&Japio
JP10088478A 1978-08-21 1978-08-21 Novel 5-(pyridyl)-2-mercaptoimidazole derivative, its preparation,and medicine containing thereof as effective component Pending JPS5528907A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10088478A JPS5528907A (en) 1978-08-21 1978-08-21 Novel 5-(pyridyl)-2-mercaptoimidazole derivative, its preparation,and medicine containing thereof as effective component

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10088478A JPS5528907A (en) 1978-08-21 1978-08-21 Novel 5-(pyridyl)-2-mercaptoimidazole derivative, its preparation,and medicine containing thereof as effective component

Publications (1)

Publication Number Publication Date
JPS5528907A true JPS5528907A (en) 1980-02-29

Family

ID=14285744

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10088478A Pending JPS5528907A (en) 1978-08-21 1978-08-21 Novel 5-(pyridyl)-2-mercaptoimidazole derivative, its preparation,and medicine containing thereof as effective component

Country Status (1)

Country Link
JP (1) JPS5528907A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8629285B2 (en) 2005-08-18 2014-01-14 Synta Pharmaceuticals Corp. Imidazole compounds that modulate HSP90 activity

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8629285B2 (en) 2005-08-18 2014-01-14 Synta Pharmaceuticals Corp. Imidazole compounds that modulate HSP90 activity
US9156794B2 (en) 2005-08-18 2015-10-13 Synta Pharmaceuticals Corp. Imidazole compounds that modulate HSP90 activity

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