JPS5528919A - Medicine comprising 5-(3'-pyridyl)-2-mercaptoimidazole derivative as active constituent - Google Patents

Medicine comprising 5-(3'-pyridyl)-2-mercaptoimidazole derivative as active constituent

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Publication number
JPS5528919A
JPS5528919A JP10140978A JP10140978A JPS5528919A JP S5528919 A JPS5528919 A JP S5528919A JP 10140978 A JP10140978 A JP 10140978A JP 10140978 A JP10140978 A JP 10140978A JP S5528919 A JPS5528919 A JP S5528919A
Authority
JP
Japan
Prior art keywords
pyridyl
active constituent
formula
mercaptoimidazole derivative
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10140978A
Other languages
Japanese (ja)
Inventor
Teruhiko Umetsu
Kazuko Sanai
Tadakatsu Kato
Katsuyuki Otsuka
Michio Tanaka
Toshiyoshi Taniguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kaken Pharmaceutical Co Ltd
Original Assignee
Kaken Pharmaceutical Co Ltd
Kaken Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaken Pharmaceutical Co Ltd, Kaken Chemical Co Ltd filed Critical Kaken Pharmaceutical Co Ltd
Priority to JP10140978A priority Critical patent/JPS5528919A/en
Publication of JPS5528919A publication Critical patent/JPS5528919A/en
Pending legal-status Critical Current

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  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE: An antithrombotic, blood platelet antiagglutinating agent, or hypotensive drug, comprising a 5-(3'-pyridyl)-2-mercaptoimidazole derivative as an active constituent.
CONSTITUTION: An antithrombotic, blood platelet antiagglutinating agent, or hypotensive drug, comprising a 5-(3'-pyridyl)-2-mercaptoimidazole derivative of the formula (R is H, lower alkyl, alkenyl, aryl or phenyl group which is substituted by halogen, or lower alkoxy group, or a lower alkyl group substituted by phenyl group) as an active constituent. The compound may be directly used as a drug, however, is usually used in a dosage form of tablets, granules, powder, syrups, ointments, embrocations, suppositories, or injections, in 100W10,000mg, particularly 200W5,000mg per day an adult for oral administration. The compound of the formula can be obtained by reacting an isothiocyanate of the formula RNCS with 3- pyridyl-aminomethyl ketone.
COPYRIGHT: (C)1980,JPO&Japio
JP10140978A 1978-08-22 1978-08-22 Medicine comprising 5-(3'-pyridyl)-2-mercaptoimidazole derivative as active constituent Pending JPS5528919A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10140978A JPS5528919A (en) 1978-08-22 1978-08-22 Medicine comprising 5-(3'-pyridyl)-2-mercaptoimidazole derivative as active constituent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10140978A JPS5528919A (en) 1978-08-22 1978-08-22 Medicine comprising 5-(3'-pyridyl)-2-mercaptoimidazole derivative as active constituent

Publications (1)

Publication Number Publication Date
JPS5528919A true JPS5528919A (en) 1980-02-29

Family

ID=14299908

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10140978A Pending JPS5528919A (en) 1978-08-22 1978-08-22 Medicine comprising 5-(3'-pyridyl)-2-mercaptoimidazole derivative as active constituent

Country Status (1)

Country Link
JP (1) JPS5528919A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0411701A2 (en) * 1989-07-31 1991-02-06 Merck & Co. Inc. Certain imidazole compounds as transglutaminase inhibitors

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0411701A2 (en) * 1989-07-31 1991-02-06 Merck & Co. Inc. Certain imidazole compounds as transglutaminase inhibitors

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