JPS57171973A - Manufacture of 4-amino-chloroquinolines - Google Patents

Manufacture of 4-amino-chloroquinolines

Info

Publication number
JPS57171973A
JPS57171973A JP57003535A JP353582A JPS57171973A JP S57171973 A JPS57171973 A JP S57171973A JP 57003535 A JP57003535 A JP 57003535A JP 353582 A JP353582 A JP 353582A JP S57171973 A JPS57171973 A JP S57171973A
Authority
JP
Japan
Prior art keywords
amino
formula
image
optionally substituted
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP57003535A
Other languages
English (en)
Japanese (ja)
Inventor
Bodouan Mishieru
Mishiyure Danieru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Sante SA
Original Assignee
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante SA filed Critical Rhone Poulenc Sante SA
Publication of JPS57171973A publication Critical patent/JPS57171973A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/46—Nitrogen atoms attached in position 4 with hydrocarbon radicals, substituted by nitrogen atoms, attached to said nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Quinoline Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP57003535A 1981-01-16 1982-01-14 Manufacture of 4-amino-chloroquinolines Pending JPS57171973A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8100765A FR2498187A1 (fr) 1981-01-16 1981-01-16 Procede de preparation d'amino-4 chloro-7 quinoleines

Publications (1)

Publication Number Publication Date
JPS57171973A true JPS57171973A (en) 1982-10-22

Family

ID=9254223

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57003535A Pending JPS57171973A (en) 1981-01-16 1982-01-14 Manufacture of 4-amino-chloroquinolines

Country Status (13)

Country Link
US (1) US4421920A (enExample)
EP (1) EP0056766B1 (enExample)
JP (1) JPS57171973A (enExample)
KR (1) KR870001921B1 (enExample)
AT (1) ATE7492T1 (enExample)
CA (1) CA1171861A (enExample)
DE (1) DE3260150D1 (enExample)
DK (1) DK148805C (enExample)
FR (1) FR2498187A1 (enExample)
HU (1) HU184985B (enExample)
IE (1) IE51957B1 (enExample)
IN (1) IN158327B (enExample)
ZA (1) ZA82277B (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993007124A1 (fr) * 1991-09-30 1993-04-15 Eisai Co., Ltd. Compose heterocyclique azote
JPH07188174A (ja) * 1993-10-28 1995-07-25 F Hoffmann La Roche Ag アミノキノリン誘導体
JP2007517837A (ja) * 2004-01-14 2007-07-05 コンセホ・スペリオール・デ・インベスティガシオネス・シエンティフィカス ピリジニウムおよびキノリニウム誘導体

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2892298A (en) * 1957-08-05 1959-06-30 Earl J Chaney Pickup device
GB8426584D0 (en) * 1984-10-19 1984-11-28 Beecham Group Plc Compounds
EP0222839A4 (en) * 1985-05-17 1988-11-09 Univ Australian ANTI-MALARIA COMPOUNDS.
US4789678A (en) * 1986-08-25 1988-12-06 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds
CA1340821C (en) * 1988-10-06 1999-11-16 Nobuyuki Fukazawa Heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components
AU6168296A (en) * 1995-06-07 1996-12-30 The Administrators Of The Tulane Eductional Fund Chloroquine analogs and methods of preventing and treating p lasmodial disease
KR100489174B1 (ko) 1996-03-05 2005-09-30 제네카-파마 소시에떼아노님 4-아닐리노퀴나졸린유도체
IL128994A (en) * 1996-09-25 2004-12-15 Zeneca Ltd History of quinoline and naphthyridine and their salts, processes for their preparation, pharmaceutical preparations containing them and their use as medicines
GB9910579D0 (en) 1999-05-08 1999-07-07 Zeneca Ltd Chemical compounds
GB9910580D0 (en) 1999-05-08 1999-07-07 Zeneca Ltd Chemical compounds
US6417177B1 (en) 1999-07-13 2002-07-09 Alpha Research Group, Llc Chloroquine derivatives for the treatment of Parkinson's disease
US20040229908A1 (en) * 1999-07-13 2004-11-18 Jodi Nelson Compositions and methods for the treatment of Parkinson's disease and tardive dyskinesias
PT1274692E (pt) * 2000-04-07 2006-11-30 Astrazeneca Ab Compostos de quinazolina
EP1337524A1 (en) * 2000-11-02 2003-08-27 AstraZeneca AB Substituted quinolines as antitumor agents
JP2004517059A (ja) * 2000-11-02 2004-06-10 アストラゼネカ アクチボラグ 抗腫瘍剤用の４−置換キノリン類
US7084157B2 (en) * 2002-05-17 2006-08-01 Rajeev Raut Ophthalmic pharmaceutical compositions and methods for treating ocular inflammation
US20040002451A1 (en) * 2002-06-20 2004-01-01 Bruce Kerwin Compositions of pegylated soluble tumor necrosis factor receptors and methods of preparing
GB0215823D0 (en) * 2002-07-09 2002-08-14 Astrazeneca Ab Quinazoline derivatives
GB0225579D0 (en) * 2002-11-02 2002-12-11 Astrazeneca Ab Chemical compounds
US6916627B2 (en) * 2002-11-27 2005-07-12 St. Jude Children's Research Hospital ATM kinase compositions and methods
US7108992B2 (en) * 2002-11-27 2006-09-19 St. Jude Children's Research Hospital ATM kinase compositions and methods
US8309562B2 (en) * 2003-07-03 2012-11-13 Myrexis, Inc. Compounds and therapeutical use thereof
KR101218213B1 (ko) 2003-07-03 2013-01-04 시토비아 인크. 카스파제의 활성인자 및 세포자멸사의 유도인자로서의4-아릴아미노-퀴나졸린
GEP20084572B (en) * 2003-12-23 2008-12-25 Pfizer Novel quinoline derivatives
US8586613B2 (en) 2004-01-14 2013-11-19 Universidad De Granada Pyridinium and quinolinium derivatives
EP1833482A4 (en) 2005-01-03 2011-02-16 Myriad Genetics Inc COMPOUNDS AND ITS THERAPEUTIC USE
US8258145B2 (en) * 2005-01-03 2012-09-04 Myrexis, Inc. Method of treating brain cancer
WO2007059372A2 (en) * 2005-11-09 2007-05-24 St. Jude Children's Research Hospital Use of chloroquine to treat metabolic syndrome
CN105693605B (zh) * 2016-03-09 2017-12-22 西安科技大学 一种光学纯(r)/(s)‑氯喹的不对称合成方法
CN105693606B (zh) * 2016-03-09 2017-12-05 西安科技大学 一种光学纯(r)/(s)‑羟氯喹的不对称合成方法
EP4251746A1 (en) 2020-11-30 2023-10-04 Cellectis SA Use of aminoquinoline compounds for higher gene integration
CN115947684B (zh) * 2023-01-18 2025-01-17 贵州医科大学 一种钯和铜协同催化氧化芳构化制备4-胺基喹啉类衍生物的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2653940A (en) * 1951-01-27 1953-09-29 William S Johnson Process for preparing 4-quinolyl secondary amines

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993007124A1 (fr) * 1991-09-30 1993-04-15 Eisai Co., Ltd. Compose heterocyclique azote
JPH07188174A (ja) * 1993-10-28 1995-07-25 F Hoffmann La Roche Ag アミノキノリン誘導体
JP2007517837A (ja) * 2004-01-14 2007-07-05 コンセホ・スペリオール・デ・インベスティガシオネス・シエンティフィカス ピリジニウムおよびキノリニウム誘導体

Also Published As

Publication number Publication date
ZA82277B (en) 1982-11-24
HU184985B (en) 1984-11-28
EP0056766A1 (fr) 1982-07-28
FR2498187A1 (fr) 1982-07-23
CA1171861A (fr) 1984-07-31
FR2498187B1 (enExample) 1983-09-30
IN158327B (enExample) 1986-10-18
DK16582A (da) 1982-07-17
IE51957B1 (en) 1987-04-29
KR870001921B1 (ko) 1987-10-22
IE820075L (en) 1982-07-16
ATE7492T1 (de) 1984-06-15
DE3260150D1 (en) 1984-06-20
KR830009038A (ko) 1983-12-17
DK148805C (da) 1986-04-01
US4421920A (en) 1983-12-20
DK148805B (da) 1985-10-07
EP0056766B1 (fr) 1984-05-16

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