JPS57142956A - Amidine derivative and anticomplementary agent - Google Patents
Amidine derivative and anticomplementary agentInfo
- Publication number
- JPS57142956A JPS57142956A JP2797381A JP2797381A JPS57142956A JP S57142956 A JPS57142956 A JP S57142956A JP 2797381 A JP2797381 A JP 2797381A JP 2797381 A JP2797381 A JP 2797381A JP S57142956 A JPS57142956 A JP S57142956A
- Authority
- JP
- Japan
- Prior art keywords
- expressed
- anticomplementary
- agent
- reaction
- formulai
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000003171 anti-complementary effect Effects 0.000 title abstract 3
- 150000001409 amidines Chemical class 0.000 title 1
- IOHPVZBSOKLVMN-UHFFFAOYSA-N 2-(2-phenylethyl)benzoic acid Chemical compound OC(=O)C1=CC=CC=C1CCC1=CC=CC=C1 IOHPVZBSOKLVMN-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 239000012048 reactive intermediate Substances 0.000 abstract 2
- UJOWLDLTHDHRKU-UHFFFAOYSA-N 4-(2-aminoethynyl)phenol Chemical compound NC#CC1=CC=C(O)C=C1 UJOWLDLTHDHRKU-UHFFFAOYSA-N 0.000 abstract 1
- 101710081722 Antitrypsin Proteins 0.000 abstract 1
- 102000016917 Complement C1 Human genes 0.000 abstract 1
- 108010028774 Complement C1 Proteins 0.000 abstract 1
- BHHQVLBZJUBCQG-UHFFFAOYSA-N [4-(3-amino-3-iminoprop-1-enyl)phenyl] benzoate;methanesulfonic acid Chemical compound CS(O)(=O)=O.C1=CC(C=CC(=N)N)=CC=C1OC(=O)C1=CC=CC=C1 BHHQVLBZJUBCQG-UHFFFAOYSA-N 0.000 abstract 1
- 150000008065 acid anhydrides Chemical class 0.000 abstract 1
- 230000001475 anti-trypsic effect Effects 0.000 abstract 1
- 239000004019 antithrombin Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000007806 chemical reaction intermediate Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000006482 condensation reaction Methods 0.000 abstract 1
- 230000018044 dehydration Effects 0.000 abstract 1
- 238000006297 dehydration reaction Methods 0.000 abstract 1
- 125000002795 guanidino group Chemical group C(N)(=N)N* 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- CKOOABJZYWLHMN-UHFFFAOYSA-N phenyl benzoate Chemical class C=1C=CC=CC=1C(=O)OC1=CC=CC=C1.C=1C=CC=CC=1C(=O)OC1=CC=CC=C1 CKOOABJZYWLHMN-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002753 trypsin inhibitor Substances 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2797381A JPS57142956A (en) | 1981-02-27 | 1981-02-27 | Amidine derivative and anticomplementary agent |
| US06/350,964 US4490388A (en) | 1981-02-27 | 1982-02-22 | Amidine compound and anticomplement agent comprising same |
| FR8203259A FR2500826B1 (fr) | 1981-02-27 | 1982-02-26 | Nouveau carboxylate de 4-(b-amidinoethenyl) phenyle, son procede de preparation et agent anti-complement en comprenant |
| GB8205700A GB2096598B (en) | 1981-02-27 | 1982-02-26 | Novel amidine compounds |
| DE3207023A DE3207023C2 (de) | 1981-02-27 | 1982-02-26 | Amidinverbindungen, Verfahren zu ihrer Herstellung und pharmazeutische Mittel, die diese Verbindungen enthalten |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2797381A JPS57142956A (en) | 1981-02-27 | 1981-02-27 | Amidine derivative and anticomplementary agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS57142956A true JPS57142956A (en) | 1982-09-03 |
| JPS6360738B2 JPS6360738B2 (enrdf_load_stackoverflow) | 1988-11-25 |
Family
ID=12235813
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2797381A Granted JPS57142956A (en) | 1981-02-27 | 1981-02-27 | Amidine derivative and anticomplementary agent |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS57142956A (enrdf_load_stackoverflow) |
-
1981
- 1981-02-27 JP JP2797381A patent/JPS57142956A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6360738B2 (enrdf_load_stackoverflow) | 1988-11-25 |
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