FR2500826B1 - Nouveau carboxylate de 4-(b-amidinoethenyl) phenyle, son procede de preparation et agent anti-complement en comprenant - Google Patents
Nouveau carboxylate de 4-(b-amidinoethenyl) phenyle, son procede de preparation et agent anti-complement en comprenantInfo
- Publication number
- FR2500826B1 FR2500826B1 FR8203259A FR8203259A FR2500826B1 FR 2500826 B1 FR2500826 B1 FR 2500826B1 FR 8203259 A FR8203259 A FR 8203259A FR 8203259 A FR8203259 A FR 8203259A FR 2500826 B1 FR2500826 B1 FR 2500826B1
- Authority
- FR
- France
- Prior art keywords
- amidinoethenyl
- novel
- preparation
- agent including
- complement agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/18—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2797381A JPS57142956A (en) | 1981-02-27 | 1981-02-27 | Amidine derivative and anticomplementary agent |
| JP14728981A JPS5849358A (ja) | 1981-09-18 | 1981-09-18 | アミジン誘導体および抗補体剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2500826A1 FR2500826A1 (fr) | 1982-09-03 |
| FR2500826B1 true FR2500826B1 (fr) | 1985-10-31 |
Family
ID=26365983
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8203259A Expired FR2500826B1 (fr) | 1981-02-27 | 1982-02-26 | Nouveau carboxylate de 4-(b-amidinoethenyl) phenyle, son procede de preparation et agent anti-complement en comprenant |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US4490388A (fr) |
| DE (1) | DE3207023C2 (fr) |
| FR (1) | FR2500826B1 (fr) |
| GB (1) | GB2096598B (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59139357A (ja) * | 1983-01-28 | 1984-08-10 | Torii Yakuhin Kk | アミジン誘導体 |
| US5238964A (en) * | 1990-04-05 | 1993-08-24 | Torii & Co., Ltd. | Agent for treatment of cerebrovascular contraction |
| KR20000005312A (ko) | 1996-04-10 | 2000-01-25 | 오노 야꾸힝 고교 가부시키가이샤 | 트립타아제 억제제 및 신규 구아니디노 유도체 |
| AU7808198A (en) | 1997-06-03 | 1998-12-21 | Biocryst Pharmaceuticals, Inc. | Novel compounds useful in the complement, coagulat and kallikrein pathways and method for their preparation |
| EP1066272A4 (fr) * | 1998-03-27 | 2002-03-13 | Biocryst Pharm Inc | Nouveaux composes utiles dans les voies du complement, de la coagulation et de la kallikreine et leur procede de preparation |
| AU3620099A (en) * | 1998-04-24 | 1999-11-16 | Proteus Molecular Design Limited | Aminomethyl-benzoic ester derivatives as tryptase inhibitors |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2575991A (en) * | 1949-03-24 | 1951-11-20 | Burroughs Wellcome Co | Cinnamamidine derivatives |
| US3579510A (en) * | 1967-08-30 | 1971-05-18 | Pfizer | 3-(hydroxy-phenyl) substituted amidines and derivatives thereof as anthelmintic agents |
| FR2233988A1 (fr) * | 1973-06-11 | 1975-01-17 | Bristol Myers Co | |
| GB1472700A (en) * | 1974-11-01 | 1977-05-04 | Ono Pharmaceutical Co | Guanidinobehzoic acid derivatives and process for preparing the same |
| DK343576A (da) * | 1975-08-04 | 1977-02-05 | Bristol Myers Co | Fremgangsmade til fremstilling af styrylamidiner |
| JPS5470241A (en) * | 1977-11-09 | 1979-06-05 | Ono Pharmaceut Co Ltd | Guanidinobenzoic acid derivative and its preparation |
-
1982
- 1982-02-22 US US06/350,964 patent/US4490388A/en not_active Expired - Lifetime
- 1982-02-26 FR FR8203259A patent/FR2500826B1/fr not_active Expired
- 1982-02-26 GB GB8205700A patent/GB2096598B/en not_active Expired
- 1982-02-26 DE DE3207023A patent/DE3207023C2/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE3207023A1 (de) | 1982-09-30 |
| GB2096598A (en) | 1982-10-20 |
| DE3207023C2 (de) | 1984-12-06 |
| FR2500826A1 (fr) | 1982-09-03 |
| GB2096598B (en) | 1985-01-09 |
| US4490388A (en) | 1984-12-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |