JPS57128654A - 19-substituted vitamin d3 derivative - Google Patents

19-substituted vitamin d3 derivative

Info

Publication number
JPS57128654A
JPS57128654A JP56011494A JP1149481A JPS57128654A JP S57128654 A JPS57128654 A JP S57128654A JP 56011494 A JP56011494 A JP 56011494A JP 1149481 A JP1149481 A JP 1149481A JP S57128654 A JPS57128654 A JP S57128654A
Authority
JP
Japan
Prior art keywords
compound
protecting group
vitamin
formula
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP56011494A
Other languages
Japanese (ja)
Inventor
Hiroaki Takayama
Sachiko Yamada
Takayoshi Suzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Priority to JP56011494A priority Critical patent/JPS57128654A/en
Publication of JPS57128654A publication Critical patent/JPS57128654A/en
Pending legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:The vitamin D3 derivative of formulaI(R is H or OH-protecting group; R' is H or lower alkyl; n is integer 2W4).
EXAMPLE: The compound of formula IV.
USE: It has physiological activity similar to vitamin D, and is useful a drug. It is also useful as a hapten for the preparation of antibody necessary for the determination of vitamin D3 in blood by the antigen-antibody reaction.
PROCESS: The compound of formulaIwherein R is OH-protecting group can be prepared by reacting the compound of formula II (R" is OH-protecting group; R is R" or H) with the compound of formula X-(CH2)n-COOR' (X is halogen), and thermally decomposing the resultant compound of formula III optionally after the removal of the OH-protecting group by conventional means.
COPYRIGHT: (C)1982,JPO&Japio
JP56011494A 1981-01-30 1981-01-30 19-substituted vitamin d3 derivative Pending JPS57128654A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP56011494A JPS57128654A (en) 1981-01-30 1981-01-30 19-substituted vitamin d3 derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56011494A JPS57128654A (en) 1981-01-30 1981-01-30 19-substituted vitamin d3 derivative

Publications (1)

Publication Number Publication Date
JPS57128654A true JPS57128654A (en) 1982-08-10

Family

ID=11779584

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56011494A Pending JPS57128654A (en) 1981-01-30 1981-01-30 19-substituted vitamin d3 derivative

Country Status (1)

Country Link
JP (1) JPS57128654A (en)

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