JPS57106692A - Novel glyceroglycolipid compound and its preparation - Google Patents

Novel glyceroglycolipid compound and its preparation

Info

Publication number
JPS57106692A
JPS57106692A JP18304980A JP18304980A JPS57106692A JP S57106692 A JPS57106692 A JP S57106692A JP 18304980 A JP18304980 A JP 18304980A JP 18304980 A JP18304980 A JP 18304980A JP S57106692 A JPS57106692 A JP S57106692A
Authority
JP
Japan
Prior art keywords
compound
acetyl
formula
benzyl
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP18304980A
Other languages
Japanese (ja)
Other versions
JPS6328072B2 (en
Inventor
Tomoya Ogawa
Kazuo Beppu
Tadami Shinnai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aska Pharmaceutical Co Ltd
Teikoku Chemical Industry Co Ltd
RIKEN Institute of Physical and Chemical Research
Original Assignee
Teikoku Chemical Industry Co Ltd
Teikoku Hormone Manufacturing Co Ltd
RIKEN Institute of Physical and Chemical Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teikoku Chemical Industry Co Ltd, Teikoku Hormone Manufacturing Co Ltd, RIKEN Institute of Physical and Chemical Research filed Critical Teikoku Chemical Industry Co Ltd
Priority to JP18304980A priority Critical patent/JPS57106692A/en
Publication of JPS57106692A publication Critical patent/JPS57106692A/en
Publication of JPS6328072B2 publication Critical patent/JPS6328072B2/ja
Granted legal-status Critical Current

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  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:The glyceroglycolipid compound of formula I[R1 is H or benzyl; Y is H, acetyl or group of formula II (R2 is H or acetyl)l.
EXAMPLE: 1-O-(3,4,6-Tri-O-benzyl-α-D-manopyranosyl)-2,3-di-O-tetradecyl-glycerol.
USE: A biochemical reagent. It is also useful as an antigen for producing specific antibody, or as an antimetabolic agent.
PROCESS: The reaction of the compound of formula III (Bn is benzyl; Ac is acetyl; X is halogen) with 1,2-di-O-tetradecylglycerol in the presence of a dehydrohalogenating agent and a silver compound and/or a mercury compound gives a compound of formula IV (R is H or acetyl), which is made to react with the compound of formula III to obtain a compound of formulaIwherein R1=Bn and Y= Ac. The compound can be converted to another compound of formulaIwherein R1=Bn and Y-H by deacetylation, and further to the compound of formulaI wherein R1=Y=H by catalytic reduction.
COPYRIGHT: (C)1982,JPO&Japio
JP18304980A 1980-12-24 1980-12-24 Novel glyceroglycolipid compound and its preparation Granted JPS57106692A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP18304980A JPS57106692A (en) 1980-12-24 1980-12-24 Novel glyceroglycolipid compound and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP18304980A JPS57106692A (en) 1980-12-24 1980-12-24 Novel glyceroglycolipid compound and its preparation

Publications (2)

Publication Number Publication Date
JPS57106692A true JPS57106692A (en) 1982-07-02
JPS6328072B2 JPS6328072B2 (en) 1988-06-07

Family

ID=16128840

Family Applications (1)

Application Number Title Priority Date Filing Date
JP18304980A Granted JPS57106692A (en) 1980-12-24 1980-12-24 Novel glyceroglycolipid compound and its preparation

Country Status (1)

Country Link
JP (1) JPS57106692A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0260606A2 (en) * 1986-09-11 1988-03-23 Mect Corporation Medicament for curing neurotic disturbance or disorder comprising sialocylglycerolipid
US4797477A (en) * 1986-08-12 1989-01-10 Mect Corporation Process for preparing sialic acid derivatives

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4797477A (en) * 1986-08-12 1989-01-10 Mect Corporation Process for preparing sialic acid derivatives
EP0260606A2 (en) * 1986-09-11 1988-03-23 Mect Corporation Medicament for curing neurotic disturbance or disorder comprising sialocylglycerolipid

Also Published As

Publication number Publication date
JPS6328072B2 (en) 1988-06-07

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