JPS57126424A - Production of human monoclonal antibody by human hybridoma - Google Patents

Production of human monoclonal antibody by human hybridoma

Info

Publication number
JPS57126424A
JPS57126424A JP56178255A JP17825581A JPS57126424A JP S57126424 A JPS57126424 A JP S57126424A JP 56178255 A JP56178255 A JP 56178255A JP 17825581 A JP17825581 A JP 17825581A JP S57126424 A JPS57126424 A JP S57126424A
Authority
JP
Japan
Prior art keywords
human
production
monoclonal antibody
hybridoma
human monoclonal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP56178255A
Other languages
English (en)
Japanese (ja)
Inventor
Emu Kurose Karuro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wistar Institute of Anatomy and Biology
Original Assignee
Wistar Institute of Anatomy and Biology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wistar Institute of Anatomy and Biology filed Critical Wistar Institute of Anatomy and Biology
Publication of JPS57126424A publication Critical patent/JPS57126424A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP56178255A 1980-11-07 1981-11-06 Production of human monoclonal antibody by human hybridoma Pending JPS57126424A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20483280A 1980-11-07 1980-11-07

Publications (1)

Publication Number Publication Date
JPS57126424A true JPS57126424A (en) 1982-08-06

Family

ID=22759633

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56178255A Pending JPS57126424A (en) 1980-11-07 1981-11-06 Production of human monoclonal antibody by human hybridoma

Country Status (12)

Country Link
JP (1) JPS57126424A (fr)
AT (1) AT380898B (fr)
AU (1) AU548738B2 (fr)
BE (1) BE891003A (fr)
CA (1) CA1198066A (fr)
CH (1) CH658070A5 (fr)
DE (1) DE3144181A1 (fr)
FR (1) FR2493865A1 (fr)
GB (1) GB2086937B (fr)
IT (1) IT1140050B (fr)
NZ (1) NZ198851A (fr)
SE (1) SE460907B (fr)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58205773A (ja) * 1982-05-27 1983-11-30 Canon Inc インクジエツトプリンタ
JPS5989697A (ja) * 1982-08-24 1984-05-23 ジエラ−ド・ダブリユ・フイツシヤ− ポリリボシルリビト−ルホスフエ−トと反応性のヒトモノクロ−ナル抗体
JPS59198970A (ja) * 1983-04-06 1984-11-10 コ−ニング・グラス・ワ−クス ハイブリドーマ細胞系
JPS6012973A (ja) * 1983-03-11 1985-01-23 スロ−ン−ケツタリング・インステイテユ−ト・フオ−・キヤンサ−・リサ−チ 悪性黒色腫のある患者のリンパ球からのヒトの単一クロ−ン抗体
JPS6024184A (ja) * 1983-03-09 1985-02-06 スロ−ン−ケツタリング・インステイテユ−ト・フオ−・キヤンサ−・リサ−チ ガン細胞に対するヒトのモノクロ−ン抗体の反応
JPS6133125A (ja) * 1984-07-25 1986-02-17 Morinaga & Co Ltd ヒト単クロ−ン性抗肺ガン細胞抗体
JPS61104796A (ja) * 1984-10-26 1986-05-23 Chemo Sero Therapeut Res Inst モノクロ−ナル抗体の製造方法
EP0368662A2 (fr) 1988-11-09 1990-05-16 MITSUI TOATSU CHEMICALS, Inc. Lignes cellulaires parentales pour la production d'hybridomes humains

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1983002058A1 (fr) * 1981-12-08 1983-06-23 Univ South Carolina Anticorps humains monocloniques ou lymphocines dans la separation de cellules ou dans le diagnostic du cancer du sein
CA1247538A (fr) * 1982-05-21 1988-12-28 Mark C. Glassy Hybridomes humain-humain contre les tumeurs solides
JPS58201994A (ja) * 1982-05-21 1983-11-25 Hideaki Hagiwara 抗原特異的ヒト免疫グロブリンの生産方法
US4618577A (en) * 1983-02-09 1986-10-21 The Regents Of The University Of California Human-human hybridoma, CLNH5
DE3379055D1 (en) * 1982-06-09 1989-03-02 Asahi Chemical Ind Method for producing human antibody
AU567693B2 (en) 1982-09-30 1987-12-03 University Of Rochester Human monoclonal antibodies against bacterial toxins
US4689299A (en) * 1982-09-30 1987-08-25 University Of Rochester Human monoclonal antibodies against bacterial toxins
CA1214123A (fr) * 1983-01-20 1986-11-18 Masashi Matsui Lignee cellulaire utilisee pour la preparation d'hybridomes
US4677070A (en) * 1985-04-26 1987-06-30 Cetus Corporation Pseudomonas aeruginosa exotoxin A antibodies, their preparation and use
EP0239102A3 (fr) * 1986-03-28 1989-07-12 Tsuji, Kimiyoshi Procédé de préparation d'un hybridome humain-humain
WO1989009789A1 (fr) * 1988-04-07 1989-10-19 Farmitalia Carlo Erba S.R.L. Anticorps monoclonaux humains contre le virus de la rage
US5750106A (en) * 1993-01-28 1998-05-12 Novartis Ag Human monoclonal antibodies to cytomegalovirus

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196265A (en) * 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies
US4172124A (en) * 1978-04-28 1979-10-23 The Wistar Institute Method of producing tumor antibodies

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PROC. NATL. ACAD. SCI.=1980US *

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58205773A (ja) * 1982-05-27 1983-11-30 Canon Inc インクジエツトプリンタ
JPS5989697A (ja) * 1982-08-24 1984-05-23 ジエラ−ド・ダブリユ・フイツシヤ− ポリリボシルリビト−ルホスフエ−トと反応性のヒトモノクロ−ナル抗体
JPS6024184A (ja) * 1983-03-09 1985-02-06 スロ−ン−ケツタリング・インステイテユ−ト・フオ−・キヤンサ−・リサ−チ ガン細胞に対するヒトのモノクロ−ン抗体の反応
JPS6012973A (ja) * 1983-03-11 1985-01-23 スロ−ン−ケツタリング・インステイテユ−ト・フオ−・キヤンサ−・リサ−チ 悪性黒色腫のある患者のリンパ球からのヒトの単一クロ−ン抗体
JPS59198970A (ja) * 1983-04-06 1984-11-10 コ−ニング・グラス・ワ−クス ハイブリドーマ細胞系
JPH0358708B2 (fr) * 1983-04-06 1991-09-06 Kooningu Inc
JPS6133125A (ja) * 1984-07-25 1986-02-17 Morinaga & Co Ltd ヒト単クロ−ン性抗肺ガン細胞抗体
JPH0429357B2 (fr) * 1984-07-25 1992-05-18
JPS61104796A (ja) * 1984-10-26 1986-05-23 Chemo Sero Therapeut Res Inst モノクロ−ナル抗体の製造方法
EP0368662A2 (fr) 1988-11-09 1990-05-16 MITSUI TOATSU CHEMICALS, Inc. Lignes cellulaires parentales pour la production d'hybridomes humains

Also Published As

Publication number Publication date
SE8106528L (sv) 1982-05-08
AU548738B2 (en) 1986-01-02
BE891003A (fr) 1982-03-01
NZ198851A (en) 1984-07-31
FR2493865A1 (fr) 1982-05-14
GB2086937A (en) 1982-05-19
AT380898B (de) 1986-07-25
GB2086937B (en) 1985-05-30
CA1198066A (fr) 1985-12-17
IT8124862A0 (it) 1981-11-04
ATA476381A (de) 1985-12-15
CH658070A5 (fr) 1986-10-15
SE460907B (sv) 1989-12-04
IT1140050B (it) 1986-09-24
AU7716781A (en) 1982-05-13
DE3144181A1 (de) 1982-09-09
FR2493865B1 (fr) 1984-12-14

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