JPS57123180A - 3-substituted beta-carboline, manufacture and psychotropic drug containing same - Google Patents

3-substituted beta-carboline, manufacture and psychotropic drug containing same

Info

Publication number
JPS57123180A
JPS57123180A JP56200237A JP20023781A JPS57123180A JP S57123180 A JPS57123180 A JP S57123180A JP 56200237 A JP56200237 A JP 56200237A JP 20023781 A JP20023781 A JP 20023781A JP S57123180 A JPS57123180 A JP S57123180A
Authority
JP
Japan
Prior art keywords
atoms
hydrogen
lower alkyl
alkyl
different
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56200237A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0557274B2 (enExample
Inventor
Neefu Giyuntaa
Eedaa Ururitsuhi
Shiyumiihien Rarufu
Fuuto Andoreasu
Raatsu Deiitaa
Zaideruman Deiitaa
Keeru Buorufugangu
Parenshiyato Deiitaa
Chiyuuko Buresutoruupu Kurausu
Anderusu Kurisutense Ierugensu
Engerusutofuto Moogensu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19803048318 external-priority patent/DE3048318A1/de
Priority claimed from DE19813136857 external-priority patent/DE3136857A1/de
Application filed by Schering AG filed Critical Schering AG
Publication of JPS57123180A publication Critical patent/JPS57123180A/ja
Publication of JPH0557274B2 publication Critical patent/JPH0557274B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Anesthesiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP56200237A 1980-12-17 1981-12-14 3-substituted beta-carboline, manufacture and psychotropic drug containing same Granted JPS57123180A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19803048318 DE3048318A1 (de) 1980-12-17 1980-12-17 4-alkoxyalkyl substituierte (beta)-carbolin-3-carbonsaeurederivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DK91381 1981-02-27
DE19813136857 DE3136857A1 (de) 1981-09-14 1981-09-14 Substituierte (beta)-carbolin-3-carbonsaeurealkylester, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
JPS57123180A true JPS57123180A (en) 1982-07-31
JPH0557274B2 JPH0557274B2 (enExample) 1993-08-23

Family

ID=27189019

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56200237A Granted JPS57123180A (en) 1980-12-17 1981-12-14 3-substituted beta-carboline, manufacture and psychotropic drug containing same

Country Status (16)

Country Link
US (2) US4435403A (enExample)
EP (1) EP0054507B1 (enExample)
JP (1) JPS57123180A (enExample)
AT (1) ATE32513T1 (enExample)
AU (1) AU558450B2 (enExample)
CA (1) CA1188300A (enExample)
DD (1) DD161210A5 (enExample)
DE (1) DE3176650D1 (enExample)
EG (1) EG17159A (enExample)
ES (1) ES508073A0 (enExample)
HU (1) HU187395B (enExample)
IE (1) IE53931B1 (enExample)
IL (1) IL64560A (enExample)
NZ (1) NZ199312A (enExample)
PT (1) PT74143B (enExample)
RO (1) RO82164A (enExample)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5989678A (ja) * 1982-10-29 1984-05-23 シエ−リング・アクチエンゲゼルシヤフト β―カルボリン、その製法および該化合物を含有する長期持続的作用を有する精神安定剤
JPS6013791A (ja) * 1983-06-23 1985-01-24 シエ−リング・アクチエンゲゼルシヤフト 新規置換β―カルボリン、その製法及び該置換β―カルボリンを含有する抗痙れん剤
JPS6013790A (ja) * 1983-06-23 1985-01-24 シエ−リング・アクチエンゲゼルシヤフト 新規置換β―カルボリン、その製法および該置換β―カルボリンを含有する鎮痙剤
JPS6041676A (ja) * 1983-05-27 1985-03-05 シエ−リング・アクチエンゲゼルシヤフト β−カルボリン−３−カルボン酸誘導体、その製法及びこれを含有する精神作用剤
JPS6140283A (ja) * 1984-05-15 1986-02-26 シエ−リング・アクチエンゲゼルシヤフト 新規β−カルボリン−３−オキサジアゾリル誘導体、その製造法及び該化合物を含有する向精神作用を有する製薬学的調製剤
JPS62167780A (ja) * 1985-11-13 1987-07-24 シエ−リング・アクチエンゲゼルシヤフト フエノキシ置換のβ−カルボリン誘導体、その製法及び該化合物を含有する不安除去−及び抗痙攣作用を有する医薬
JPS62221684A (ja) * 1986-03-20 1987-09-29 シエ−リング・アクチエンゲゼルシヤフト ５−または６−置換β−カルボリン−３−カルボン酸エステル、その製法およびこれを含有する精神病薬
JPS6468369A (en) * 1987-08-17 1989-03-14 Merck & Co Inc Cholecystokinin and beta carbolins as gastrin antagonist
JPS6468370A (en) * 1987-08-28 1989-03-14 Schering Ag Isoxazole beta carboline derivative, manufacture and central nervous system remedy

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ194747A (en) * 1979-08-29 1988-11-29 Schering Ag 9h-pyrido(3,4-b)indol-3-ylcarboxylic acid derivatives
DK151808C (da) * 1982-11-16 1988-06-20 Ferrosan As Analogifremgangsmaade til fremstilling af oxadiazolylimidazo-oe1,4aa-benzodiazepinderivater
DE3246932A1 (de) * 1982-12-16 1984-06-20 Schering AG, 1000 Berlin und 4709 Bergkamen Substituierte 5h-pyrimido(5,4-b)indole
US4631149A (en) * 1983-07-25 1986-12-23 University Of Illinois Antiviral eudistomins from a marine tunicate
DE3335323A1 (de) 1983-09-27 1985-04-04 Schering AG, 1000 Berlin und 4709 Bergkamen Substituierte ss-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
NZ210850A (en) * 1984-01-19 1988-10-28 Hoffmann La Roche Imidazodiazepine derivatives and pharmaceutical compositions
DK240184D0 (da) * 1984-05-15 1984-05-15 Ferrosan As Beta-carboline-3-carboxylic acid derivatives and method of preparing the same
GB8432073D0 (en) * 1984-12-19 1985-01-30 Roussel Lab Ltd Chemical compounds
DE3504045A1 (de) * 1985-02-04 1986-08-07 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von ss-carbolinen durch dehydrierung
AU587802B2 (en) * 1985-03-08 1989-08-31 Ferrosan A/S Novel oxadiazolyl imidazobenzodiazepine derivatives and methods of preparing such compounds
US4745112A (en) * 1985-05-17 1988-05-17 A/S Ferrosan Oxadiazolylimidazobenzodiazepine, compositions, and method III
US4622320A (en) * 1985-05-17 1986-11-11 As Ferrosan Oxadiazolylimidazobenzodiazepine, compositions, and method
DE3535927A1 (de) * 1985-10-04 1987-04-09 Schering Ag 3-vinyl- und 3-ethinyl-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
DE3540653A1 (de) * 1985-11-13 1987-05-14 Schering Ag Neue 3-oxadiazol- und 3-carbonsaeure-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
DE3545776A1 (de) * 1985-12-20 1987-06-25 Schering Ag 5-aminoalkyl-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
US4952584A (en) * 1986-01-11 1990-08-28 Beecham Group P.L.C. 9H-pyrido[2,B-8]indole-3-carboxylic acid ester compounds having useful pharmaceutical activity
DE3608089A1 (de) * 1986-03-08 1987-09-10 Schering Ag Heteroaryl-oxy-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
DK174086D0 (da) * 1986-04-16 1986-04-16 Ferrosan As Nye benzodiazepinderivater samt fremgangsmaade til fremstilling af samme
DE3729370C2 (de) * 1987-08-31 1995-04-20 Schering Ag Verfahren zur Herstellung von 4-Alkoxyalkyl-beta-carbolinen
DE3943225A1 (de) * 1989-12-23 1991-06-27 Schering Ag Neue ss-carboline, verfahren zu deren herstellung und deren verwendung in arzneimitteln
DE4013907A1 (de) * 1990-04-26 1991-10-31 Schering Ag Verfahren zur herstellung von gramin-derivaten
DE4029389A1 (de) * 1990-09-13 1992-03-26 Schering Ag Verfahren zur herstellung von (beta)-carbolin-derivaten
US5350750A (en) * 1991-04-27 1994-09-27 Schering Aktiengesellschaft β-carboline-3-hydroxyalkylcarboxylic acid ester derivatives, process for their production and their use in pharmaceutical agents
US5543519A (en) * 1991-06-15 1996-08-06 Schering Aktiengesellschaft 3-aryl or 3-hetaryl-β-carbolines, their production and use in pharmaceutical agents
DE4120109A1 (de) * 1991-06-15 1992-12-17 Schering Ag 3-aryl- oder 3-hetaryl-(beta)-carboline, deren herstellung und verwendung in arzneimitteln
DE4122722A1 (de) * 1991-07-06 1993-01-07 Schering Ag Verfahren zur herstellung von indol-derivaten
DE4130933A1 (de) * 1991-09-13 1993-03-18 Schering Ag Neue (beta)-carbolinderivate, deren herstellung und verwendung in arzneimitteln
US5585490A (en) * 1991-10-08 1996-12-17 Neurogen Corporation Certain cycloalkyl and azacycloalkyl pyrrolopyrimidines; a new class of GABA brain receptor ligands
WO1994025463A1 (en) * 1992-04-08 1994-11-10 Neurogen Corporation Certain aryl fused pyrrolopyrimidines; a new class of gaba brain receptor ligands
US5367077A (en) * 1992-04-08 1994-11-22 Neurogen Corporation Certain cycloalkyl and azacycloalkyl pyrrolopyridines; a new class of gaba rain receptor ligands
US5286860A (en) * 1992-11-12 1994-02-15 Neurogen Corporation Certain aryl substituted pyrrolopyrazines; a new class of GABA brain receptor ligands
US5750702A (en) * 1993-10-27 1998-05-12 Neurogen Corporation Certain pyrrolo pyridine-3-carboxamides; a new class of GABA brain receptor ligands
DE4330175A1 (de) * 1993-08-31 1995-03-02 Schering Ag Alkoxy-substituierte beta-Carboline
US5484944A (en) * 1993-10-27 1996-01-16 Neurogen Corporation Certain fused pyrrolecarboxanilides and their use as GABA brain receptor ligands
US6211365B1 (en) 1996-01-19 2001-04-03 Neurogen Corporation Fused pyrrolecarboxamides; a new class of GABA brain receptor ligands
US5804686A (en) * 1996-01-19 1998-09-08 Neurogen Corporation fused pyrrolecarboxamides; a new class of GABA brain receptor ligands
EP0888300A1 (en) 1996-03-22 1999-01-07 Neurogen Corporation Certain fused pyrrolecarboxamides as gaba brain receptor ligands
US5723462A (en) * 1996-04-26 1998-03-03 Neurogen Corporation Certain fused pyrrolecarboxamides a new class of GABA brain receptor ligands
US20050014939A1 (en) * 1999-08-31 2005-01-20 Neurogen Corporation Fused pyrrolecarboxamides: GABA brain receptor ligands
EE200200111A (et) * 1999-08-31 2003-06-16 Neurogen Corporation Kondenseerunud pürroolkarboksamiidid: aju GABA-retseptori ligandid
US20040253891A1 (en) * 2000-09-12 2004-12-16 Schierenbeck Alan W. Composite structure for protective garment
US20050143371A1 (en) * 2003-07-23 2005-06-30 Pharmacia Corporation Beta-carboline compounds and analogues thereof as mitogen-activated protein kinase-activated protein kinase-2 inhibitors
FR2953837B1 (fr) * 2009-12-10 2012-03-09 Sanofi Aventis Derives 9h-pyridino[3,4-b]indole disubstitues, leur preparation et leur utilisation therapeutique
FR2953838B1 (fr) * 2009-12-10 2012-02-24 Sanofi Aventis Derives de 9h-beta-carboline (ou 9h-pyridino[3,4-b]indole) trisubstitues, leur preparation et leur utilisation therapeutique
EP3860996A4 (en) 2018-10-02 2022-08-31 Northwestern University BETA-CARBOLINES AS POSITIVE ALLOSTERIC MODULATORS OF HUMAN SEROTONIN RECEPTOR 2C (5-HT2C)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51122097A (en) * 1975-04-11 1976-10-25 Roussel Uclaf Novel derivative of *9h* pyrid *3*44b* indole and salt thereof * production of same and pharmaceutical composition
JPS55145687A (en) * 1979-04-26 1980-11-13 Synthelabo Pyridoindoles and their manufacture
JPS574987A (en) * 1980-06-09 1982-01-11 Sankyo Co Ltd Pyridoindolecarboxylic acid derivative and its preparation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA786351A (en) 1968-05-28 Leonard Frederick PROCESS FOR THE PREPARATION OF NEW .beta.-CARBOLIN-CARBOXYLIC ACID AMIDE DERIVATIVES
FR894620A (fr) 1943-02-08 1944-12-29 Barrere & Cie M Embrayeur-inverseur pour la commande des arbres porte-hélice des bateaux
ES273769A1 (es) * 1961-01-18 1962-06-01 Geigy Ag J R Procedimiento para la preparaciën de nuevos derivados de amidas de acido beta-carbolin-carboxilico
NZ194747A (en) * 1979-08-29 1988-11-29 Schering Ag 9h-pyrido(3,4-b)indol-3-ylcarboxylic acid derivatives

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51122097A (en) * 1975-04-11 1976-10-25 Roussel Uclaf Novel derivative of *9h* pyrid *3*44b* indole and salt thereof * production of same and pharmaceutical composition
JPS55145687A (en) * 1979-04-26 1980-11-13 Synthelabo Pyridoindoles and their manufacture
JPS574987A (en) * 1980-06-09 1982-01-11 Sankyo Co Ltd Pyridoindolecarboxylic acid derivative and its preparation

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5989678A (ja) * 1982-10-29 1984-05-23 シエ−リング・アクチエンゲゼルシヤフト β―カルボリン、その製法および該化合物を含有する長期持続的作用を有する精神安定剤
JPS6041676A (ja) * 1983-05-27 1985-03-05 シエ−リング・アクチエンゲゼルシヤフト β−カルボリン−３−カルボン酸誘導体、その製法及びこれを含有する精神作用剤
JPS6013791A (ja) * 1983-06-23 1985-01-24 シエ−リング・アクチエンゲゼルシヤフト 新規置換β―カルボリン、その製法及び該置換β―カルボリンを含有する抗痙れん剤
JPS6013790A (ja) * 1983-06-23 1985-01-24 シエ−リング・アクチエンゲゼルシヤフト 新規置換β―カルボリン、その製法および該置換β―カルボリンを含有する鎮痙剤
JPS6140283A (ja) * 1984-05-15 1986-02-26 シエ−リング・アクチエンゲゼルシヤフト 新規β−カルボリン−３−オキサジアゾリル誘導体、その製造法及び該化合物を含有する向精神作用を有する製薬学的調製剤
JPS62167780A (ja) * 1985-11-13 1987-07-24 シエ−リング・アクチエンゲゼルシヤフト フエノキシ置換のβ−カルボリン誘導体、その製法及び該化合物を含有する不安除去−及び抗痙攣作用を有する医薬
JPS62221684A (ja) * 1986-03-20 1987-09-29 シエ−リング・アクチエンゲゼルシヤフト ５−または６−置換β−カルボリン−３−カルボン酸エステル、その製法およびこれを含有する精神病薬
JPS6468369A (en) * 1987-08-17 1989-03-14 Merck & Co Inc Cholecystokinin and beta carbolins as gastrin antagonist
JPS6468370A (en) * 1987-08-28 1989-03-14 Schering Ag Isoxazole beta carboline derivative, manufacture and central nervous system remedy

Also Published As

Publication number Publication date
EP0054507A3 (en) 1982-09-15
IE53931B1 (en) 1989-04-26
RO82164B (ro) 1983-06-30
CA1188300A (en) 1985-06-04
EG17159A (en) 1990-12-30
PT74143A (de) 1982-01-01
NZ199312A (en) 1989-08-29
ATE32513T1 (de) 1988-03-15
US4596808A (en) 1986-06-24
JPH0557274B2 (enExample) 1993-08-23
ES8301984A1 (es) 1983-02-01
AU7859281A (en) 1982-06-24
RO82164A (ro) 1983-07-07
ES508073A0 (es) 1983-02-01
IE812954L (en) 1982-06-17
AU558450B2 (en) 1987-01-29
IL64560A (en) 1988-05-31
EP0054507B1 (en) 1988-02-17
DE3176650D1 (en) 1988-03-24
HU187395B (en) 1985-12-28
PT74143B (de) 1983-05-16
IL64560A0 (en) 1982-03-31
EP0054507A2 (en) 1982-06-23
DD161210A5 (de) 1985-06-12
US4435403A (en) 1984-03-06

Similar Documents

Publication Publication Date Title
JPS57123180A (en) 3-substituted beta-carboline, manufacture and psychotropic drug containing same
ES8106142A1 (es) Un procedimiento para la preparacion de un indol
PT82386A (en) Process for preparing dichloraniline derivatives
IL87150A0 (en) 8,9-anellated-1,2,3,4-tetrahydro-beta-carboline derivatives,their preparation and pharmaceutical compositions containing them
HU908283D0 (en) Fungicide preparation containing substituted azolyl-methyl-cycloalcanoles and process for the production of the active agents
ES424477A1 (es) Procedimiento de obtencion de composiciones organosilicicaspara el tratamiento antiadherente de materiales celulosicos o sinteticos.
DE3674110D1 (de) Indolinonderivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung.
IL62841A (en) 1,4-dihydropyridine derivatives,their production and pharmaceutical compositions containing them
EP0130141A3 (en) Beta-carbolines, process for their preparation and their use as medicaments
GB1510977A (en) Tetrahydropyridine and piperidine derivatives and processes for the production thereof
GB1513948A (en) Thiazolidine derivatives and process for their manufactur
NZ182556A (en) Tricylick azacyloalkanones
KR830002664A (ko) 알데히드-에테르의 제조방법
ES475157A1 (es) Un procedimiento para la preparacion de nuevos derivados de bencenosulfonamida y bencenocarboxamina.
SE7902354L (sv) Nya fungicida kompositioner for bekempning av svampsjukdomar hos vexter och innehaller sasom verksam bestandsdel isotiouroniumfosfiter
ES483253A1 (es) Un procedimiento para la prepracion de derivados de pipera- zin-2,5-diona.
ES8607939A1 (es) Procedimiento de preparacion de nuevos derivados de la 8-al-coxicarbonilaminoisoquinolina y de sus sales de adicion aci-da
FI813437L (fi) Biologisesti aktiivisia trisyklisiae amiineja,niiden valmistusmenetelmae ja niitae sisaeltaeviae farmaseuttisia koostumuksia
ATE83232T1 (de) Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
ZA899321B (en) Indole derivatives,process for preparing them and pharmaceutical compositions containing them
ES8300083A1 (es) Procedimiento para la obtencion de derivados de 2-amino-etanol.
ES470462A1 (es) Procedimiento para producir imidazol-2-carbamatos
ES8102116A1 (es) Un procedimiento para preparar benzoxepinas
ES432464A1 (es) Procedimiento para la preparacion de nuevos derivados de bi-fenilo.
DE3162110D1 (en) Cycloalkano-thiazolyloxamidic-acid derivatives, process for their preparation and pharmaceutical compositions containing them