JPS57118574A - N-(4-phenylthiazol-2-yl)carbamate derivative, its preparation and medicinal composition containing the same - Google Patents
N-(4-phenylthiazol-2-yl)carbamate derivative, its preparation and medicinal composition containing the sameInfo
- Publication number
- JPS57118574A JPS57118574A JP273981A JP273981A JPS57118574A JP S57118574 A JPS57118574 A JP S57118574A JP 273981 A JP273981 A JP 273981A JP 273981 A JP273981 A JP 273981A JP S57118574 A JPS57118574 A JP S57118574A
- Authority
- JP
- Japan
- Prior art keywords
- phenylthiazol
- preparation
- carbamate derivative
- same
- composition containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:An N-(4-phenylthiazol-2-yl)carbamate derivative of formulaI(R1 is halogen, lower alkyl, lower alkoxyl, lower alkylthio, phenyl, carboxyalkyl aralkyloxycarbonylalkyl; R2 is H, lower alkyl or lower alkoxyl; R3 is lower halogenoalkyl).
EXAMPLE: 2,2,2-Trichloroethyl N-(5-chloro-4-phenylthiazol-2-yl)carbamate.
USE: A medicine, having immunological regulating and antarthritic actions, effective against immune diseases, e.g. chronic rheumarthritis, and effective for viral diseases and anticancer immunotherapy with low toxicity.
PROCESS: A 2-amino-4-phenylthiazole of formula II is reacted with a chloroformic ester of formula III to give the compound of formulaI.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP273981A JPS57118574A (en) | 1981-01-13 | 1981-01-13 | N-(4-phenylthiazol-2-yl)carbamate derivative, its preparation and medicinal composition containing the same |
IT25957/81A IT1142649B (en) | 1981-01-08 | 1981-12-31 | N 4 Phenyl 2 thiazolyl carbamate derivs. |
PCT/JP1982/000011 WO1982002386A1 (en) | 1981-01-13 | 1982-01-13 | Aminothiazole derivatives,process for their preparation,and medicinal composition containing same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP273981A JPS57118574A (en) | 1981-01-13 | 1981-01-13 | N-(4-phenylthiazol-2-yl)carbamate derivative, its preparation and medicinal composition containing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57118574A true JPS57118574A (en) | 1982-07-23 |
JPH0254347B2 JPH0254347B2 (en) | 1990-11-21 |
Family
ID=11537704
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP273981A Granted JPS57118574A (en) | 1981-01-08 | 1981-01-13 | N-(4-phenylthiazol-2-yl)carbamate derivative, its preparation and medicinal composition containing the same |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57118574A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6475475A (en) * | 1987-09-14 | 1989-03-22 | Hisamitsu Pharmaceutical Co | Novel substituted diphenylthizole derivative |
WO1992015570A1 (en) * | 1991-03-07 | 1992-09-17 | Hisamitsu Pharmaceutical Co., Inc. | Novel diphenylthyazole derivative |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5461172A (en) * | 1977-10-19 | 1979-05-17 | Fabre Sa Pierre | Novel 44phenyll22aminothiazole derivative* its manufacture and immunity stimulant containing it |
-
1981
- 1981-01-13 JP JP273981A patent/JPS57118574A/en active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5461172A (en) * | 1977-10-19 | 1979-05-17 | Fabre Sa Pierre | Novel 44phenyll22aminothiazole derivative* its manufacture and immunity stimulant containing it |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6475475A (en) * | 1987-09-14 | 1989-03-22 | Hisamitsu Pharmaceutical Co | Novel substituted diphenylthizole derivative |
WO1992015570A1 (en) * | 1991-03-07 | 1992-09-17 | Hisamitsu Pharmaceutical Co., Inc. | Novel diphenylthyazole derivative |
Also Published As
Publication number | Publication date |
---|---|
JPH0254347B2 (en) | 1990-11-21 |
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