JPS57118574A - N-(4-phenylthiazol-2-yl)carbamate derivative, its preparation and medicinal composition containing the same - Google Patents

N-(4-phenylthiazol-2-yl)carbamate derivative, its preparation and medicinal composition containing the same

Info

Publication number
JPS57118574A
JPS57118574A JP273981A JP273981A JPS57118574A JP S57118574 A JPS57118574 A JP S57118574A JP 273981 A JP273981 A JP 273981A JP 273981 A JP273981 A JP 273981A JP S57118574 A JPS57118574 A JP S57118574A
Authority
JP
Japan
Prior art keywords
phenylthiazol
preparation
carbamate derivative
same
composition containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP273981A
Other languages
Japanese (ja)
Other versions
JPH0254347B2 (en
Inventor
Isao Sakano
Tatsuro Yokoyama
Seitaro Kajitani
Yutaka Okazaki
Hiroshi Tokuda
Hiroshi Kawamo
Mikio Kumakura
Takuo Nakano
Akira Awaya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Toatsu Chemicals Inc
Original Assignee
Mitsui Toatsu Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals Inc filed Critical Mitsui Toatsu Chemicals Inc
Priority to JP273981A priority Critical patent/JPS57118574A/en
Priority to IT25957/81A priority patent/IT1142649B/en
Priority to PCT/JP1982/000011 priority patent/WO1982002386A1/en
Publication of JPS57118574A publication Critical patent/JPS57118574A/en
Publication of JPH0254347B2 publication Critical patent/JPH0254347B2/ja
Granted legal-status Critical Current

Links

Abstract

NEW MATERIAL:An N-(4-phenylthiazol-2-yl)carbamate derivative of formulaI(R1 is halogen, lower alkyl, lower alkoxyl, lower alkylthio, phenyl, carboxyalkyl aralkyloxycarbonylalkyl; R2 is H, lower alkyl or lower alkoxyl; R3 is lower halogenoalkyl).
EXAMPLE: 2,2,2-Trichloroethyl N-(5-chloro-4-phenylthiazol-2-yl)carbamate.
USE: A medicine, having immunological regulating and antarthritic actions, effective against immune diseases, e.g. chronic rheumarthritis, and effective for viral diseases and anticancer immunotherapy with low toxicity.
PROCESS: A 2-amino-4-phenylthiazole of formula II is reacted with a chloroformic ester of formula III to give the compound of formulaI.
COPYRIGHT: (C)1982,JPO&Japio
JP273981A 1981-01-08 1981-01-13 N-(4-phenylthiazol-2-yl)carbamate derivative, its preparation and medicinal composition containing the same Granted JPS57118574A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP273981A JPS57118574A (en) 1981-01-13 1981-01-13 N-(4-phenylthiazol-2-yl)carbamate derivative, its preparation and medicinal composition containing the same
IT25957/81A IT1142649B (en) 1981-01-08 1981-12-31 N 4 Phenyl 2 thiazolyl carbamate derivs.
PCT/JP1982/000011 WO1982002386A1 (en) 1981-01-13 1982-01-13 Aminothiazole derivatives,process for their preparation,and medicinal composition containing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP273981A JPS57118574A (en) 1981-01-13 1981-01-13 N-(4-phenylthiazol-2-yl)carbamate derivative, its preparation and medicinal composition containing the same

Publications (2)

Publication Number Publication Date
JPS57118574A true JPS57118574A (en) 1982-07-23
JPH0254347B2 JPH0254347B2 (en) 1990-11-21

Family

ID=11537704

Family Applications (1)

Application Number Title Priority Date Filing Date
JP273981A Granted JPS57118574A (en) 1981-01-08 1981-01-13 N-(4-phenylthiazol-2-yl)carbamate derivative, its preparation and medicinal composition containing the same

Country Status (1)

Country Link
JP (1) JPS57118574A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6475475A (en) * 1987-09-14 1989-03-22 Hisamitsu Pharmaceutical Co Novel substituted diphenylthizole derivative
WO1992015570A1 (en) * 1991-03-07 1992-09-17 Hisamitsu Pharmaceutical Co., Inc. Novel diphenylthyazole derivative

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5461172A (en) * 1977-10-19 1979-05-17 Fabre Sa Pierre Novel 44phenyll22aminothiazole derivative* its manufacture and immunity stimulant containing it

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5461172A (en) * 1977-10-19 1979-05-17 Fabre Sa Pierre Novel 44phenyll22aminothiazole derivative* its manufacture and immunity stimulant containing it

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6475475A (en) * 1987-09-14 1989-03-22 Hisamitsu Pharmaceutical Co Novel substituted diphenylthizole derivative
WO1992015570A1 (en) * 1991-03-07 1992-09-17 Hisamitsu Pharmaceutical Co., Inc. Novel diphenylthyazole derivative

Also Published As

Publication number Publication date
JPH0254347B2 (en) 1990-11-21

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