JPS57181012A - Drug composed of polyprenyl compound - Google Patents

Drug composed of polyprenyl compound

Info

Publication number
JPS57181012A
JPS57181012A JP6424481A JP6424481A JPS57181012A JP S57181012 A JPS57181012 A JP S57181012A JP 6424481 A JP6424481 A JP 6424481A JP 6424481 A JP6424481 A JP 6424481A JP S57181012 A JPS57181012 A JP S57181012A
Authority
JP
Japan
Prior art keywords
group
formula
compound
polyprenyl compound
active component
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6424481A
Other languages
Japanese (ja)
Inventor
Isao Yamatsu
Yuichi Inai
Shinya Abe
Takeshi Suzuki
Yoshikazu Suzuki
Osamu Tagaya
Koichi Suzuki
Koichi Abe
Koji Yamada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Priority to JP6424481A priority Critical patent/JPS57181012A/en
Priority to EP19810109393 priority patent/EP0059258B1/en
Priority to DE8181109393T priority patent/DE3163920D1/en
Publication of JPS57181012A publication Critical patent/JPS57181012A/en
Pending legal-status Critical Current

Links

Abstract

PURPOSE: To provide a drug containing a polyprenyl compound as an active component, and useful as a carcinostatic agent having low toxicity and extremely high safety and administrable without causing the problem of hypervitamin A diseases, and as a remedy for various dermatoses such as senile keratosis, etc.
CONSTITUTION: The drug contains the polyprenyl compound of formulaI(n and m are 0W2; n+m is 0W2; A is group of formula II, etc.; B is group of formula III, etc.; R is hydroxyl, lower alkoxy, or group of formula IV; R1 and R2 are H, lower alkyl or aryl; provided then when n=1, m=0, A is group of formula II and B is group of formula V, that R is lower alkoxy or group of formula IV), as an active component. The compound of formulaIincludes the known compounds such as 6,10,14-trimethyl-3,5,9,13-pentadecatetraen-2-one, etc., and novel compounds such as 3,7,11,15-tetramethyl-2,4,6-hexadecatrienoic acid, etc.
COPYRIGHT: (C)1982,JPO&Japio
JP6424481A 1980-12-24 1981-04-30 Drug composed of polyprenyl compound Pending JPS57181012A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP6424481A JPS57181012A (en) 1981-04-30 1981-04-30 Drug composed of polyprenyl compound
EP19810109393 EP0059258B1 (en) 1980-12-24 1981-10-30 Pharmaceutical preparations comprising polyprenyl compounds, especially as anti-cancer agents, and pharmaceutical compositions for the prevention and treatment of cancer and skin diseases
DE8181109393T DE3163920D1 (en) 1980-12-24 1981-10-30 Pharmaceutical preparations comprising polyprenyl compounds, especially as anti-cancer agents, and pharmaceutical compositions for the prevention and treatment of cancer and skin diseases

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6424481A JPS57181012A (en) 1981-04-30 1981-04-30 Drug composed of polyprenyl compound

Publications (1)

Publication Number Publication Date
JPS57181012A true JPS57181012A (en) 1982-11-08

Family

ID=13252535

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6424481A Pending JPS57181012A (en) 1980-12-24 1981-04-30 Drug composed of polyprenyl compound

Country Status (1)

Country Link
JP (1) JPS57181012A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6172715A (en) * 1984-09-18 1986-04-14 Kao Corp Anti-inflammatory agent for external use
JP2013540762A (en) * 2010-10-01 2013-11-07 ディーエスエム アイピー アセッツ ビー．ブイ． Improved synthesis of peretinoin

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57106618A (en) * 1980-12-24 1982-07-02 Eisai Co Ltd Anticancer agent consisting of polyprenyl compound

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57106618A (en) * 1980-12-24 1982-07-02 Eisai Co Ltd Anticancer agent consisting of polyprenyl compound

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6172715A (en) * 1984-09-18 1986-04-14 Kao Corp Anti-inflammatory agent for external use
JPH0552291B2 (en) * 1984-09-18 1993-08-05 Kao Corp
JP2013540762A (en) * 2010-10-01 2013-11-07 ディーエスエム アイピー アセッツ ビー．ブイ． Improved synthesis of peretinoin

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