JPS57106617A - Analgesic and anti-inflammatory agent - Google Patents

Analgesic and anti-inflammatory agent

Info

Publication number
JPS57106617A
JPS57106617A JP55182684A JP18268480A JPS57106617A JP S57106617 A JPS57106617 A JP S57106617A JP 55182684 A JP55182684 A JP 55182684A JP 18268480 A JP18268480 A JP 18268480A JP S57106617 A JPS57106617 A JP S57106617A
Authority
JP
Japan
Prior art keywords
compound
formula
configuration
analgesic
formulai
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP55182684A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0135806B2 (https=
Inventor
Atsusuke Terada
Hidekazu Mitsusaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Priority to JP55182684A priority Critical patent/JPS57106617A/ja
Priority to US06/331,616 priority patent/US4400534A/en
Priority to DE8181306042T priority patent/DE3161290D1/de
Priority to DK570381A priority patent/DK162166C/da
Priority to EP81306042A priority patent/EP0055588B1/en
Priority to ES508337A priority patent/ES8305298A1/es
Publication of JPS57106617A publication Critical patent/JPS57106617A/ja
Publication of JPH0135806B2 publication Critical patent/JPH0135806B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/54—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings and other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP55182684A 1980-12-23 1980-12-23 Analgesic and anti-inflammatory agent Granted JPS57106617A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP55182684A JPS57106617A (en) 1980-12-23 1980-12-23 Analgesic and anti-inflammatory agent
US06/331,616 US4400534A (en) 1980-12-23 1981-12-17 Analgesic and anti-inflammatory agents
DE8181306042T DE3161290D1 (en) 1980-12-23 1981-12-22 Analgesic and anti-inflammatory agents
DK570381A DK162166C (da) 1980-12-23 1981-12-22 Analogifremgangsmaade til fremstilling af (2s)-isomere af 2-oe4-(2-hydroxycyclopentan-1-ylmethyl)phenylaapropionsyre eller farmaceutisk acceptable salte deraf
EP81306042A EP0055588B1 (en) 1980-12-23 1981-12-22 Analgesic and anti-inflammatory agents
ES508337A ES8305298A1 (es) 1980-12-23 1981-12-23 Un procedimiento para la preparacion de un isomero (25) del acido 2-(4-(2-hidroxiciclopentan-1-ilmetil)fenil)propionico.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55182684A JPS57106617A (en) 1980-12-23 1980-12-23 Analgesic and anti-inflammatory agent

Publications (2)

Publication Number Publication Date
JPS57106617A true JPS57106617A (en) 1982-07-02
JPH0135806B2 JPH0135806B2 (https=) 1989-07-27

Family

ID=16122620

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55182684A Granted JPS57106617A (en) 1980-12-23 1980-12-23 Analgesic and anti-inflammatory agent

Country Status (6)

Country Link
US (1) US4400534A (https=)
EP (1) EP0055588B1 (https=)
JP (1) JPS57106617A (https=)
DE (1) DE3161290D1 (https=)
DK (1) DK162166C (https=)
ES (1) ES8305298A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6038323A (ja) * 1983-08-10 1985-02-27 Sankyo Co Ltd 眼科用消炎剤
JPS62242616A (ja) * 1986-04-14 1987-10-23 Sankyo Co Ltd ロキソプロフエン・ナトリウム含有製剤

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58105939A (ja) * 1981-12-18 1983-06-24 Sankyo Co Ltd 置換フエニル酢酸誘導体及びその製法
JPS59196839A (ja) * 1983-04-21 1984-11-08 Sankyo Co Ltd フエニル酢酸誘導体
GB9019191D0 (en) * 1990-09-03 1990-10-17 Shell Int Research Cyclopentanol derivatives
CN1046935C (zh) * 1993-01-06 1999-12-01 久光制药株式会社 苯基烷酸衍生物,其制备方法及其光学异构体分离方法
IT1282660B1 (it) * 1996-02-21 1998-03-31 Chemi Spa Processo per produrre l'acido (t) 2- 4-2-oxociclopentilmetil) fenilpropionico ed i suoi sali
JP4202250B2 (ja) 2001-07-25 2008-12-24 バイオマリン ファーマシューティカル インコーポレイテッド 血液脳関門輸送を調節するための組成物および方法
EP2671507A3 (en) 2005-04-28 2014-02-19 Proteus Digital Health, Inc. Pharma-informatics system
MX2009002893A (es) 2006-09-18 2009-07-10 Raptor Pharmaceutical Inc Tratamiento de trastornos hepaticos mediante la administracion de conjugados de la proteina asociada al receptor (rap).
CA2752373C (en) 2009-02-20 2017-10-10 To-Bbb Holding B.V. Glutathione-based drug delivery system
IL255113B (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
KR101451171B1 (ko) * 2012-10-25 2014-10-16 한미정밀화학주식회사 록소프로펜 (2s, 1''r, 2''s) 트랜스-알코올의 제조방법
KR101465025B1 (ko) 2013-02-27 2014-11-26 한미정밀화학주식회사 입체선택적인 록소프로펜 (2s, 1''r, 2''s) 트랜스-알코올의 제조방법
CN106045842B (zh) * 2016-06-16 2018-03-27 南京海融制药有限公司 一种制备洛索洛芬活性代谢物的方法
CN111825548B (zh) * 2019-04-23 2023-06-20 南京海融医药科技股份有限公司 一种含有芳基丙酸类化合物的药物组合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3649678A (en) * 1964-04-24 1972-03-14 Warner Lambert Co Substituted cycloalkane-alkanoic acids
US4181736A (en) * 1971-09-04 1980-01-01 Laboratoires Jacques Logeais Phenylacetic acid derivatives and therapeutic composition containing same
GB1580193A (en) * 1976-04-22 1980-11-26 Nat Res Dev Phenyl acetic acid derivatives

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6038323A (ja) * 1983-08-10 1985-02-27 Sankyo Co Ltd 眼科用消炎剤
JPS62242616A (ja) * 1986-04-14 1987-10-23 Sankyo Co Ltd ロキソプロフエン・ナトリウム含有製剤

Also Published As

Publication number Publication date
EP0055588A1 (en) 1982-07-07
DK162166C (da) 1992-03-16
DE3161290D1 (en) 1983-12-01
ES508337A0 (es) 1983-04-01
DK162166B (da) 1991-09-23
DK570381A (da) 1982-06-24
EP0055588B1 (en) 1983-10-26
ES8305298A1 (es) 1983-04-01
JPH0135806B2 (https=) 1989-07-27
US4400534A (en) 1983-08-23

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