DE3161290D1 - Analgesic and anti-inflammatory agents - Google Patents

Analgesic and anti-inflammatory agents

Info

Publication number
DE3161290D1
DE3161290D1 DE8181306042T DE3161290T DE3161290D1 DE 3161290 D1 DE3161290 D1 DE 3161290D1 DE 8181306042 T DE8181306042 T DE 8181306042T DE 3161290 T DE3161290 T DE 3161290T DE 3161290 D1 DE3161290 D1 DE 3161290D1
Authority
DE
Germany
Prior art keywords
analgesic
inflammatory agents
inflammatory
agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8181306042T
Other languages
German (de)
Inventor
Eiichi Biological Resea Misaka
Atsusuke Terada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Application granted granted Critical
Publication of DE3161290D1 publication Critical patent/DE3161290D1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/54—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings and other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
DE8181306042T 1980-12-23 1981-12-22 Analgesic and anti-inflammatory agents Expired DE3161290D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55182684A JPS57106617A (en) 1980-12-23 1980-12-23 Analgesic and anti-inflammatory agent

Publications (1)

Publication Number Publication Date
DE3161290D1 true DE3161290D1 (en) 1983-12-01

Family

ID=16122620

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8181306042T Expired DE3161290D1 (en) 1980-12-23 1981-12-22 Analgesic and anti-inflammatory agents

Country Status (6)

Country Link
US (1) US4400534A (en)
EP (1) EP0055588B1 (en)
JP (1) JPS57106617A (en)
DE (1) DE3161290D1 (en)
DK (1) DK162166C (en)
ES (1) ES8305298A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58105939A (en) * 1981-12-18 1983-06-24 Sankyo Co Ltd Substituted phenylacetic acid derivative and its preparation
JPS59196839A (en) * 1983-04-21 1984-11-08 Sankyo Co Ltd Phenylacetic acid derivative
JPS6038323A (en) * 1983-08-10 1985-02-27 Sankyo Co Ltd Ophthalmic anti-inflammatory agent
JPH0774153B2 (en) * 1986-04-14 1995-08-09 三共株式会社 Loxoprofen / sodium-containing preparation
GB9019191D0 (en) * 1990-09-03 1990-10-17 Shell Int Research Cyclopentanol derivatives
CN1046935C (en) * 1993-01-06 1999-12-01 久光制药株式会社 Phenylalkan derivative, preparation of same and seperation of optical isomer of same
IT1282660B1 (en) * 1996-02-21 1998-03-31 Chemi Spa PROCESS TO PRODUCE (T) 2- 4-2-OXOCYCLOPENTYL METHYL) PHENYLPROPIONIC ACID AND ITS SALTS
EP1554572B1 (en) 2001-07-25 2009-10-14 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
CN103259027A (en) 2005-04-28 2013-08-21 普罗透斯数字保健公司 Pharma-informatics system
CA2663377A1 (en) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
EP2398500B1 (en) 2009-02-20 2019-03-13 2-BBB Medicines B.V. Glutathione-based drug delivery system
CA2760945A1 (en) 2009-05-06 2010-11-11 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
KR101451171B1 (en) * 2012-10-25 2014-10-16 한미정밀화학주식회사 Manufacturing method of (Loxoprofen (2S, 1'R, 2'S) trans-alcohol
KR101465025B1 (en) 2013-02-27 2014-11-26 한미정밀화학주식회사 The stereoselective manufacturing method of loxoprofen(2s, 1'r, 2'r) trans-alcohol
CN106045842B (en) * 2016-06-16 2018-03-27 南京海融制药有限公司 A kind of method for preparing loxoprofen active metabolite
CN111825548B (en) * 2019-04-23 2023-06-20 南京海融医药科技股份有限公司 Pharmaceutical composition containing aryl propionic acid compound

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3649678A (en) * 1964-04-24 1972-03-14 Warner Lambert Co Substituted cycloalkane-alkanoic acids
US4181736A (en) * 1971-09-04 1980-01-01 Laboratoires Jacques Logeais Phenylacetic acid derivatives and therapeutic composition containing same
GB1580193A (en) * 1976-04-22 1980-11-26 Nat Res Dev Phenyl acetic acid derivatives

Also Published As

Publication number Publication date
EP0055588A1 (en) 1982-07-07
JPH0135806B2 (en) 1989-07-27
DK570381A (en) 1982-06-24
EP0055588B1 (en) 1983-10-26
ES508337A0 (en) 1983-04-01
US4400534A (en) 1983-08-23
DK162166C (en) 1992-03-16
ES8305298A1 (en) 1983-04-01
DK162166B (en) 1991-09-23
JPS57106617A (en) 1982-07-02

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