ES8305298A1 - Un procedimiento para la preparacion de un isomero (25) del acido 2-(4-(2-hidroxiciclopentan-1-ilmetil)fenil)propionico. - Google Patents

Un procedimiento para la preparacion de un isomero (25) del acido 2-(4-(2-hidroxiciclopentan-1-ilmetil)fenil)propionico.

Info

Publication number
ES8305298A1
ES8305298A1 ES508337A ES508337A ES8305298A1 ES 8305298 A1 ES8305298 A1 ES 8305298A1 ES 508337 A ES508337 A ES 508337A ES 508337 A ES508337 A ES 508337A ES 8305298 A1 ES8305298 A1 ES 8305298A1
Authority
ES
Spain
Prior art keywords
inflammatory agents
image
analgesic
salts
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES508337A
Other languages
English (en)
Other versions
ES508337A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Publication of ES508337A0 publication Critical patent/ES508337A0/es
Publication of ES8305298A1 publication Critical patent/ES8305298A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/54—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings and other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE UN ISOMERO (2S) DEL ACIDO 2- 4-(2-HIDROXICICLOPENTAN-1-ELMETIL)FENIL PROPIONICO. CONSISTE EN LA RESOLUCION DE UN ISOMERO (2S) DEL ACIDO, O DE UN PRECURSOR DEL MISMO, A PARTIR DE LA MEZCLA DE LOS ISOMEROS (2S) Y (2R), SEGUIDA DE LA EVENTUAL CONVERSION DEL PRECURSOR PRESUELTO EN EL CORRESPONDIENTE ISOMERO (2S) DEL ACIDO Y DE SU SALIFICACION. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO AGENTES ANALGESICOS Y ANTIINFLAMATORIOS.
ES508337A 1980-12-23 1981-12-23 Un procedimiento para la preparacion de un isomero (25) del acido 2-(4-(2-hidroxiciclopentan-1-ilmetil)fenil)propionico. Expired ES8305298A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55182684A JPS57106617A (en) 1980-12-23 1980-12-23 Analgesic and anti-inflammatory agent

Publications (2)

Publication Number Publication Date
ES508337A0 ES508337A0 (es) 1983-04-01
ES8305298A1 true ES8305298A1 (es) 1983-04-01

Family

ID=16122620

Family Applications (1)

Application Number Title Priority Date Filing Date
ES508337A Expired ES8305298A1 (es) 1980-12-23 1981-12-23 Un procedimiento para la preparacion de un isomero (25) del acido 2-(4-(2-hidroxiciclopentan-1-ilmetil)fenil)propionico.

Country Status (6)

Country Link
US (1) US4400534A (es)
EP (1) EP0055588B1 (es)
JP (1) JPS57106617A (es)
DE (1) DE3161290D1 (es)
DK (1) DK162166C (es)
ES (1) ES8305298A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58105939A (ja) * 1981-12-18 1983-06-24 Sankyo Co Ltd 置換フエニル酢酸誘導体及びその製法
JPS59196839A (ja) * 1983-04-21 1984-11-08 Sankyo Co Ltd フエニル酢酸誘導体
JPS6038323A (ja) * 1983-08-10 1985-02-27 Sankyo Co Ltd 眼科用消炎剤
JPH0774153B2 (ja) * 1986-04-14 1995-08-09 三共株式会社 ロキソプロフェン・ナトリウム含有製剤
GB9019191D0 (en) * 1990-09-03 1990-10-17 Shell Int Research Cyclopentanol derivatives
CN1046935C (zh) * 1993-01-06 1999-12-01 久光制药株式会社 苯基烷酸衍生物,其制备方法及其光学异构体分离方法
IT1282660B1 (it) * 1996-02-21 1998-03-31 Chemi Spa Processo per produrre l'acido (t) 2- 4-2-oxociclopentilmetil) fenilpropionico ed i suoi sali
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
SI1889198T1 (sl) 2005-04-28 2015-02-27 Proteus Digital Health, Inc. Farma-informacijski sistem
MX2009002893A (es) 2006-09-18 2009-07-10 Raptor Pharmaceutical Inc Tratamiento de trastornos hepaticos mediante la administracion de conjugados de la proteina asociada al receptor (rap).
WO2010095940A2 (en) 2009-02-20 2010-08-26 To-Bbb Holding B.V. Glutathione-based drug delivery system
NZ596876A (en) 2009-05-06 2014-01-31 Lab Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
KR101451171B1 (ko) * 2012-10-25 2014-10-16 한미정밀화학주식회사 록소프로펜 (2s, 1''r, 2''s) 트랜스-알코올의 제조방법
KR101465025B1 (ko) 2013-02-27 2014-11-26 한미정밀화학주식회사 입체선택적인 록소프로펜 (2s, 1''r, 2''s) 트랜스-알코올의 제조방법
CN106045842B (zh) * 2016-06-16 2018-03-27 南京海融制药有限公司 一种制备洛索洛芬活性代谢物的方法
CN111825548B (zh) * 2019-04-23 2023-06-20 南京海融医药科技股份有限公司 一种含有芳基丙酸类化合物的药物组合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3649678A (en) * 1964-04-24 1972-03-14 Warner Lambert Co Substituted cycloalkane-alkanoic acids
US4181736A (en) * 1971-09-04 1980-01-01 Laboratoires Jacques Logeais Phenylacetic acid derivatives and therapeutic composition containing same
GB1580193A (en) * 1976-04-22 1980-11-26 Nat Res Dev Phenyl acetic acid derivatives

Also Published As

Publication number Publication date
JPS57106617A (en) 1982-07-02
DK162166C (da) 1992-03-16
ES508337A0 (es) 1983-04-01
DK162166B (da) 1991-09-23
US4400534A (en) 1983-08-23
DK570381A (da) 1982-06-24
EP0055588B1 (en) 1983-10-26
JPH0135806B2 (es) 1989-07-27
DE3161290D1 (en) 1983-12-01
EP0055588A1 (en) 1982-07-07

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